- Clazolam
-
Clazolam 
Systematic (IUPAC) name 2-chloro-5-methyl-5,9,10,14b-tetrahydroisoquino[2,1-d][1,4]benzodiazepin-6(7H)-one Clinical data Pregnancy cat. ? Legal status ? Identifiers CAS number 7492-29-7
10171-69-4 (HCl)ATC code None PubChem CID 24107 ChemSpider 22534 UNII YJ53T77095 
KEGG D03531 Chemical data Formula C18H17ClN2O Mol. mass 312.79 g/mol SMILES eMolecules & PubChem Clazolam[1] (SAH-1123), also referred to as isoquinazepon, is a drug which is a fused benzodiazepine and tetrahydroisoquinoline derivative.[2] It was developed in the 1960s but was never marketed.[2] It possesses anxiolytic effects and is also claimed to have antidepressant properties.[2][3]
See also
References
- ^ NL Patent 6510987
- ^ a b c David J. Triggle (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 0-412-46630-9. http://books.google.com/books?id=DeX7jgInYFMC&lpg=PA476&dq=clazolam&pg=PA476#v=onepage&q=clazolam&f=false.
- ^ Potikha LM, Kovtunenko VA (2009). "Synthesis and properties of 3-aminodihydroisoquinolines". Russian Chemical Reviews 78 (6): 513–533. doi:10.1070/RC2009v078n06ABEH004041. http://www.turpion.org/php/paper.phtml?journal_id=rc&paper_id=4041.
Benzodiazepine derivatives 1,4-Benzodiazepines Bromazepam · Camazepam · Carburazepam · Chlordiazepoxide · Cinolazepam · Clonazepam · Clorazepate · Cyprazepam · Delorazepam · Demoxepam · Devazepide * · Diazepam · Doxefazepam · Elfazepam · Ethyl carfluzepate · Ethyl dirazepate · Ethyl loflazepate · Fletazepam · Fludiazepam · Flunitrazepam · Flurazepam · Flutemazepam · Flutoprazepam · Fosazepam · Gidazepam · Halazepam · Iclazepam · Ketazolam · Lorazepam · Lormetazepam · Meclonazepam · Medazepam · Menitrazepam · Metaclazepam · Motrazepam · Nimetazepam · Nitrazepam · Nitrazepate · Nordazepam · Nortetrazepam · Oxazepam · Phenazepam · Pinazepam · Pivoxazepam · Prazepam · Proflazepam · Quazepam · QH-II-66 · Reclazepam · Ro5-2904 · Ro5-4864 * · Sulazepam · Temazepam · Tetrazepam · Tifluadom * · Tolufazepam · Tuclazepam · Uldazepam
1,5-Benzodiazepines Arfendazam · Clobazam · CP-1414S · Lofendazam · Triflubazam
2,3-Benzodiazepines * Girisopam · GYKI-52466 · GYKI-52895 · Nerisopam · Talampanel · Tofisopam
Triazolobenzodiazepines Adinazolam · Alprazolam · Estazolam · Flubromazolam · Triazolam
Imidazobenzodiazepines Bretazenil · Climazolam · FG-8205 · Flumazenil · Imidazenil · L-655,708 · Loprazolam · Midazolam · PWZ-029 · Remimazolam · Ro15-4513 · Ro48-6791 · Ro48-8684 · Sarmazenil · SH-053-R-CH3-2′F
Oxazolobenzodiazepines Cloxazolam · Flutazolam · Haloxazolam · Mexazolam · Oxazolam
Thienodiazepines Bentazepam · Brotizolam · Ciclotizolam · Clotiazepam · Etizolam · Olanzapine *
Pyridodiazepines Lopirazepam · Zapizolam
Pyrazolodiazepines Pyrrolodiazepines Tetrahydroisoquinobenzodiazepines Clazolam
Benzodiazepine prodrugs * atypical activity profile (not GABAA receptor ligands)GABAA receptor PAMs Barbiturates Allobarbital • Alphenal • Amobarbital • Aprobarbital • Barbexaclone • Barbital • Benzobarbital • Benzylbutylbarbiturate • Brallobarbital • Brophebarbital • Bucolome • Butabarbital • Butalbital • Butobarbital • Butallylonal • Carbubarb • Crotylbarbital • Cyclobarbital • Cyclopal • Enallylpropymal • Ethallobarbital • Febarbamate • Heptabarbital • Hexethal • Hexobarbital • Mephobarbital • Metharbital • Methohexital • Methylphenobarbital • Narcobarbital • Nealbarbital • Pentobarbital • Phenobarbital • Phetharbital • Primidone • Prazitone • Probarbital • Propallylonal • Proxibarbal • Proxibarbital • Reposal • Secbutabarbital • Secobarbital • Sigmodal • Spirobarbital • Talbutal • Thialbarbital • Thiamylal • Thiobarbital • Thiobutabarbital • Thiopental • Valofane • Vinbarbital • VinylbitalBenzodiazepines Adinazolam • Alprazolam • Arfendazam • Avizafone • Bentazepam • Bretazenil • Bromazepam • Brotizolam • Camazepam • Chlordiazepoxide • Ciclotizolam • Cinolazepam • Clazolam • Climazolam • Clobazam • Clonazepam • Clorazepate • Clotiazepam • Cloxazolam • Cyprazepam • Delorazepam • Diazepam • Doxefazepam • Elfazepam • Estazolam • Ethyl carfluzepate • Ethyl dirazepate • Ethyl loflazepate • Etizolam • Fletazepam • Fludiazepam • Flunitrazepam • Flurazepam • Flutazolam • Flutemazepam • Flutoprazepam • Fosazepam • Gidazepam • Girisopam • Halazepam • Haloxazolam • Iclazepam • Imidazenil • Ketazolam • Lofendazam • Lopirazepam • Lopirazepam • Loprazolam • Lorazepam • Lormetazepam • Meclonazepam • Medazepam • Menitrazepam • Metaclazepam • Mexazolam • Midazolam • Nerisopam • Nimetazepam • Nitrazepam • Nitrazepate • Nordazepam • Oxazepam • Oxazolam • Phenazepam • Pinazepam • Pivoxazepam • Prazepam • Premazepam • Proflazepam • QH-II-66 • Quazepam • Reclazepam • Remimazolam • Rilmazafone • Ripazepam • Ro48-6791 • SH-053-R-CH3-2′F • Sulazepam • Temazepam • Tetrazepam • Tofisopam • Triazolam • Triflubazam • Uldazepam • Zapizolam • Zolazepam • ZomebazamCarbamates Carisbamate • Carisoprodol • Emylcamate • Ethinamate • Febarbamate • Felbamate • Hexapropymate • Mebutamate • Meprobamate • Methocarbamol • Phenprobamate • Procymate • Styramate • TybamateNeuroactive steroids Acebrochol • Allopregnanolone • Alphadolone • Alphaxolone • Ganaxolone • Hydroxydione • Minaxolone • Org 20599 • THDOCNonbenzodiazepines β-Carbolines: Abecarnil • Gedocarnil • SL-651,498 • ZK-93423; Cyclopyrrolones: Eszopiclone • Pagoclone • Pazinaclone • Suproclone • Suriclone • Zopiclone; Imidazopyridines: Alpidem • Necopidem • Saripidem • Zolpidem; Pyrazolopyrimidines: Divaplon • Fasiplon • Indiplon • Lorediplon • Ocinaplon • Panadiplon • Taniplon • Zaleplon; Others: Adipiplon • CGS-8216 • CGS-9896 • CGS-13767 • CGS-20625 • CL-218,872 • CP-615,003 • ELB-139 • GBLD-345 • L-838,417 • NS-2664 • NS-2710 • NS-11394 • Pipequaline • ROD-188 • RWJ-51204 • SB-205,384 • SX-3228 • TP-003 • TPA-023 • TP-13 • U-89843A • U-90042 • Y-23684Phenols Piperidinediones Pyrazolopyridines Cartazolate • Etazolate • ICI-190,622 • TracazolateQuinazolinones Volatiles/gases 2-Methyl-2-butanol • Acetone • Acetophenone • Acetylglycinamide chloral hydrate • Benzene • Butane • Butanol • Butylene • Centalun • Chloral • Chloral hydrate • Chlorobutanol • Chloroform • Cyclopropane • Desflurane • Dichloromethane • Diethyl ether • Enflurane • Ethanol (Alcohol) • Ethyl chloride • Ethylene • Gasoline • Halothane • Isoflurane • Kerosine • Menthol • Methanol • Methoxyflurane • Methoxypropane • Methylbutanol • Nitric oxide • Nitrogen • Nitrous oxide • Paraldehyde • Pentanol • Propane • Propanol • Propylene • Sevoflurane • Toluene • Trichloroethanol • Trichloroethylene • Vinyl ether • XenonOthers Bromide (Lithium bromide, Potassium bromide, Sodium bromide) • Chloralodol • Chloralose • Chlormezanone • Clomethiazole • DEABL • Ethchlorvynol • Etifoxine • Etomidate • GABA • Kavalactones (Kava) • Loreclezole • Methylpentynol • Metomidate • Petrichloral • Propanidid • Skullcap • Stiripentol • Sulfonmethane • Tetronal • Triclofos • Trional • Valeric acid, Valerenic acid (Valerian)Categories:- Anxiolytics
- Lactams
- Organochlorides
- Benzodiazepines
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