Fletazepam

Drugbox
IUPAC_name = 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1,4-benzodiazepine

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CAS_number=34482-99-0
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PubChem=36834
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C=17 | H=13 | Cl=1 | F=4 | N=2
molecular_weight = 356.745
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Fletazepam is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is mainly notable for its strong muscle relaxant properties. [Barnett A, Goldstein J, Fiedler EP, Taber RI. The pharmacology of fletazepam, a centrally-acting muscle relaxant. "Archives Internationales de Pharmacodynamie et de Therapie". 1974 Nov;212(1):164-74.]

Fletazepam is most closely related to other N-trifluoroethyl substituted benzodiazepines such as halazepam and quazepam. [Orio LC, Barnett A, Billard W. Selective affinity of 1-N-trifluoroethyl benzodiazepines for cerebellar type 1 receptor sites. "Life Sciences", 1984. (35):105-113.]

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