Climazolam

Climazolam
Climazolam
Systematic (IUPAC) name
8-chloro-6-(2-chlorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 59467-77-5
ATCvet code QN05CD90
PubChem CID 68790
ChemSpider 62030
UNII O9KZB9HG1Y YesY
KEGG D07714
Chemical data
Formula C18H13Cl2N3 
Mol. mass 342.222
SMILES eMolecules & PubChem

Climazolam[1] (Ro21-3982) is a drug which is an imidazobenzodiazepine derivative developed by Hoffman-LaRoche. It is similar in structure to triazolam, and is used in veterinary medicine for anaesthetising animals.[2][3]

See also



References

  1. ^ FR Patent 228589
  2. ^ Ganter M, Kanngiesser M. Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine. (German) Zentralblatt fur Veterinarmedizin. Reihe A. 1991 Aug;38(7):501-9. PMID 1950241
  3. ^ Bettschart-Wolfensberger R, Taylor PM, Sear JW, Bloomfield MR, Rentsch K, Dawling S. Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine. American Journal of Veterinary Research. 1996 Oct;57(10):1472-7. PMID 8896687
v · d · eBenzodiazepine derivatives
1,4-Benzodiazepines

Bromazepam · Camazepam · Carburazepam · Chlordiazepoxide · Cinolazepam · Clonazepam · Clorazepate · Cyprazepam · Delorazepam · Demoxepam · Devazepide * · Diazepam · Doxefazepam · Elfazepam · Ethyl carfluzepate · Ethyl dirazepate · Ethyl loflazepate · Fletazepam · Fludiazepam · Flunitrazepam · Flurazepam · Flutemazepam · Flutoprazepam · Fosazepam · Gidazepam · Halazepam · Iclazepam · Ketazolam · Lorazepam · Lormetazepam · Meclonazepam · Medazepam · Menitrazepam · Metaclazepam · Motrazepam · Nimetazepam · Nitrazepam · Nitrazepate · Nordazepam · Nortetrazepam · Oxazepam · Phenazepam · Pinazepam · Pivoxazepam · Prazepam · Proflazepam · Quazepam · QH-II-66 · Reclazepam · Ro5-2904 · Ro5-4864 * · Sulazepam · Temazepam · Tetrazepam · Tifluadom * · Tolufazepam · Tuclazepam · Uldazepam
1,5-Benzodiazepines

Arfendazam · Clobazam · CP-1414S · Lofendazam · Triflubazam
2,3-Benzodiazepines *

Girisopam · GYKI-52466 · GYKI-52895 · Nerisopam · Talampanel · Tofisopam
Triazolobenzodiazepines

Adinazolam · Alprazolam · Estazolam · Flubromazolam · Triazolam
Imidazobenzodiazepines

Bretazenil · Climazolam · FG-8205 · Flumazenil · Imidazenil · L-655,708 · Loprazolam · Midazolam · PWZ-029 · Remimazolam · Ro15-4513 · Ro48-6791 · Ro48-8684 · Sarmazenil · SH-053-R-CH3-2′F
Oxazolobenzodiazepines
Thienodiazepines
Pyridodiazepines

Lopirazepam · Zapizolam
Pyrazolodiazepines

Razobazam * · Ripazepam · Zolazepam · Zomebazam
Pyrrolodiazepines
Tetrahydroisoquinobenzodiazepines
Benzodiazepine prodrugs
 * atypical activity profile (not GABAA receptor ligands)


Stub icon This sedative-related article is a stub. You can help Wikipedia by expanding it.