Menitrazepam

Menitrazepam
Menitrazepam
Systematic (IUPAC) name
5-cyclohex-1-en-1-yl-1-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 28781-64-8 YesY
ATC code None
PubChem CID 189875
ChemSpider 164902 YesY
UNII 1243654WZK YesY
Chemical data
Formula C16H17N3O3 
Mol. mass 299.32
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

Menitrazepam[1] is a drug which is a benzodiazepine derivative.[2][3] It is similar in structure to tetrazepam and nimetazepam, with the 7-chloro group of tetrazepam replaced by nitro. It is a hypnotic agent used in the treatment of insomnia, and therefore has strong sedative, anticonvulsant, muscle relaxant, and anxiolytic actions like those of other hypnotic benzodiazepines. Menitrazepam is a good oral hypnotic agent, however, delay in the time for peak plasma levels to reach their maximum brings into question the benefit of menitrazepam for the treatment of insomnia when compared to other hypnotics. Typically, the sleep inducing properties of hypnotics occur within 0.5 hours. In some cases, as with temazepam and nitrazepam, strong hypnotic effects can be felt 15 to 20 minutes after oral ingestion.



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