Halazepam

Drugbox
IUPAC_name = "9-chloro-6-phenyl-2-(2,2,2-trifluoroethyl)-2,5-diazabicyclo"
" [5.4.0] undeca-5,8,10,12-tetraen-3-one"

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width=220

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CAS_number=23092-17-3
ATC_prefix=N05
ATC_suffix=BA13
ATC_supplemental=
PubChem=31640
DrugBank=APRD01009
C=17 | H=12 | Cl=1 | F=3 | N=2 | O=1
molecular_weight = 352.7
bioavailability= ?
metabolism = Hepatic
elimination_half-life= ?
excretion = Renal
pregnancy_category = ?
legal_status = Schedule IV (US)
routes_of_administration= Oral

Halazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a trifluoromethyl derivative of nordazepam.cite journal | first = D. J. | last = Greenblatt | coauthors = A. Locniskar and R. I. Shader | date = June 12, 1982 | title = Halazepam, another precursor of desmethyldiazepam | journal = Lancet | volume = 1 | issue = 8285 | pages = 1358–9 | pmid = 6123659] While its structure may be similar to chlordiazepoxide and diazepam, it has both less toxicity and less tendency to cause paradoxical hostility and aggression than either of them.cite journal | first = W. E. | last = Fann | coauthors = W. M. Pitts and J. C. Wheless | month = Mar-Apr | year = 1982 | title = Pharmacology, efficacy, and adverse effects of halazepam, a new benzodiazepine | journal = Pharmacotherapy | volume = 2 | issue = 2 | pages = 72–9 | pmid = 6152591]

References

ee also

*nordazepam
*diazepam
*chlordiazepoxide
*Benzodiazepines

External links

* [http://www.inchem.org/documents/pims/pharm/pim160.htm Inchem - Halazepam]