Divaplon

Divaplon: Divaplon

Systematic (IUPAC) name

(6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)-phenylmethanone

Clinical data

Pregnancy cat. ?

Legal status ?

Identifiers

CAS number 90808-12-1

ATC code None

PubChem CID 65822

UNII 4AOV43246G^Y

Chemical data

Formula C₁₇H₁₇N₃O₂

Mol. mass 295.336

SMILES eMolecules & PubChem

Y(what is this?) (verify)

Divaplon (RU-32698) is a nonbenzodiazepine, anxiolytic and anticonvulsant drug from the pyrazolopyrimidine family of drugs. It acts as a partial agonist at the "benzodiazepine site" of the GABA_A receptor in the brain.^[1]^[2]^[3]

References

^ Feely, M; Boyland, P; Picardo, A; Cox, A; Gent, JP (1989). "Lack of anticonvulsant tolerance with RU 32698 and Ro 17-1812". European journal of pharmacology 164 (2): 377–80. doi:10.1016/0014-2999(89)90482-2. PMID 2759183.

^ Sanger, DJ; Joly, D; Perrault, G (1995). "Benzodiazepine (omega) receptor partial agonists and the acquisition of conditioned fear in mice". Psychopharmacology 121 (1): 104–8. doi:10.1007/BF02245596. PMID 8539334.

^ Pellón, R; Ruíz, A; Lamas, E; Rodríguez, C (2007). "Pharmacological analysis of the effects of benzodiazepines on punished schedule-induced polydipsia in rats". Behavioural pharmacology 18 (1): 81–7. doi:10.1097/FBP.0b013e3280143212. PMID 17218801.

v · d · eAnxiolytics (N05B)

GABA_A PAMs

Benzodiazepine

Adinazolam • Alprazolam • Bretazenil • Bromazepam • Camazepam • Chlordiazepoxide • Clobazam • Clonazepam • Clorazepate • Clotiazepam • Cloxazolam • Diazepam • Ethyl Loflazepate • Etizolam • Fludiazepam • Halazepam • Imidazenil • Ketazolam • Lorazepam • Medazepam • Nordazepam • Oxazepam • Pinazepam • Prazepam

Carbamates

Emylcamate • Mebutamate • Meprobamate (Carisoprodol, Tybamate) • Phenprobamate • Procymate

Nonbenzodiazepines

Abecarnil • Adipiplon • Alpidem • CGS-8216 • CGS-9896 • CGS-13767 • CGS-20625 • Divaplon • ELB-139 • Fasiplon • GBLD-345 • Gedocarnil • L-838,417 • NS-2664 • NS-2710 • Ocinaplon • Pagoclone • Panadiplon • Pipequaline • RWJ-51204 • SB-205,384 • SL-651,498 • Taniplon • TP-003 • TP-13 • TPA-023 • Y-23684 • ZK-93423

Pyrazolopyridines

Cartazolate • Etazolate • ICI-190,622 • Tracazolate

Others

Chlormezanone • Ethanol (Alcohol) • Etifoxine • Kavalactones (Kava Kava) • Skullcap • Valerenic Acid (Valerian)

α₂δ VDCC Blockers
Gabapentin • Pregabalin

5-HT_1A Agonists
Azapirones: Buspirone • Gepirone • Tandospirone; Others: Flesinoxan • Oxaflozane

H₁ Antagonists
Diphenylmethanes: Captodiame • Hydroxyzine; Others: Brompheniramine • Chlorpheniramine • Pheniramine

CRH₁ Antagonists
Antalarmin • CP-154,526 • Pexacerfont • Pivagabine

NK₂ Antagonists
GR-159,897 • Saredutant

MCH₁ antagonists
ATC-0175 • SNAP-94847

mGluR₂_/₃ Agonists
Eglumegad

mGluR5 NAMs
Fenobam

TSPO agonists
DAA-1097 • DAA-1106 • Emapunil • FGIN-127 • FGIN-143

σ₁ agonists
Afobazole • Opipramol

Others
Benzoctamine • Carbetocin • Demoxytocin • Mephenoxalone • Mepiprazole • Oxanamide • Oxytocin • Promoxolane • Tofisopam • Trimetozine • WAY-267,464

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: PSO/PSI

mepr

dsrd (o, p, m, p, a, d, s), sysi/epon, spvo

proc(eval/thrp), drug(N5A/5B/5C/6A/6B/6D)

Categories:
Anxiolytics
Ketones
Ethers
Imidazopyrimidines

Divaplon

Systematic (IUPAC) name
(6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)-phenylmethanone
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	90808-12-1
ATC code	None
PubChem	CID 65822
UNII	4AOV43246G^Y
Chemical data
Formula	C₁₇H₁₇N₃O₂
Mol. mass	295.336
SMILES	eMolecules & PubChem
Y(what is this?) (verify)

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

Nonbenzodiazepine — The nonbenzodiazepines, also called benzodiazepine like drugs, are a class of psychoactive drugs pharmacologically resembling the benzodiazepines, with similar benefits, side effects and risks, despite having dissimilar or entirely different… … Wikipedia
Clazolam — Systematic (IUPAC) name 2 chloro 5 methyl 5,9,10,14b tetrahydroisoquino[2,1 d][1,4]benzodiazepin 6(7H) one Clinical data Pregnancy cat … Wikipedia
Anxiolytic — An anxiolytic (also antipanic or antianxiety agent[1]) is a drug used for the treatment of anxiety, and its related psychological and physical symptoms. Anxiolytics have been shown to be useful in the treatment of anxiety disorders. Beta receptor … Wikipedia
Benzodiazepine — Benzodiazepines … Wikipedia
Monoamine oxidase inhibitor — MAOI redirects here. For the Easter Island statues, see Moai. Monoamine oxidase Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs prescribed for the treatment of depression. They are particularly effective in treating… … Wikipedia
Sodium thiopental — Systematic (IUPAC) name … Wikipedia
Toluene — IUPAC name … Wikipedia
Nitrous oxide — N2O redirects here. For other uses, see N2O (disambiguation). Laughing gas redirects here. For other uses, see Laughing gas (disambiguation). Not to be confused with nitric oxide (formula NO) or nitrogen dioxide (formula NO2). For other uses, see … Wikipedia
Phenylalanine — Phe redirects here. For other uses, see Phe (disambiguation). Phenylalanine … Wikipedia
Stimulant — Ritalin Slow Release (SR) 20 mg tablets. Stimulants (also referred to as psychostimulants) are psychoactive drugs which induce temporary improvements in either mental or physical function or both. Examples of these kinds of effects may include… … Wikipedia

Academic Dictionaries and Encyclopedias

Divaplon

References

Look at other dictionaries:

Share the article and excerpts

Academic Dictionaries and Encyclopedias

Wikipedia

Divaplon

References

Look at other dictionaries:

Share the article and excerpts

Direct link