Cloroqualone

Cloroqualone: Cloroqualone

Systematic (IUPAC) name

3-(2,6-Dichlorophenyl)-2-ethyl-4-quinazolinone

Clinical data

Pregnancy cat. ?

Legal status ?

Routes ?

Pharmacokinetic data

Bioavailability ?

Metabolism ?

Half-life ?

Excretion ?

Identifiers

CAS number 25509-07-3

ATC code None

PubChem CID 63338

DrugBank ?

ChemSpider 57005^Y

UNII 172D4Q6LOW^Y

Chemical data

Formula C₁₆H₁₂Cl₂N₂O

Mol. mass 319.185

SMILES eMolecules & PubChem

InChI

InChI=1S/C16H12Cl2N2O/c1-2-14-19-13-9-4-3-6-10(13)16(21)20(14)15-11(17)7-5-8-12(15)18/h3-9H,2H2,1H3^Y
Key:SONHVLIDLXLSOL-UHFFFAOYSA-N^Y

Y(what is this?) (verify)

Cloroqualone is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other European countries. It has sedative and antitussive properties, and was sold either alone or in combination with other ingredients as a cough medicine.^[1] Cloroqualone has weaker sedative properties than methaqualone and was sold for its useful cough-suppressing effects, but was withdrawn from the French market in 1994 because of concerns about its potential for abuse and overdose.

See also

Methaqualone

Afloqualone

Etaqualone

Methylmethaqualone

Mecloqualone

Mebroqualone

Diproqualone

References

^ http://www.biam2.org/www/Sub1818.html

v · d · eHypnotics/Sedatives (N05C)

GABA_A Agonists/PAMs
Barbiturates: Allobarbital • Amobarbital • Aprobarbital • Barbital • Butabarbital • Butobarbital • Cyclobarbital • Ethallobarbital • Heptabarbital • Hexobarbital • Mephobarbital • Methohexital • Pentobarbital • Phenobarbital • Proxibarbal • Reposal • Secobarbital • Talbutal • Thiamylal • Thiopental • Vinbarbital • Vinylbital; Benzodiazepines: Brotizolam • Cinolazepam • Climazolam • Doxefazepam • Estazolam • Flunitrazepam • Flurazepam • Flutoprazepam • Haloxazolam • Loprazolam • Lormetazepam • Midazolam • Nimetazepam • Nitrazepam • Quazepam • Temazepam • Triazolam; Carbamates: Carisoprodol • Ethinamate • Hexapropymate • Meprobamate • Methocarbamol • Procymate • Tybamate; Neuroactive Steroids: Acebrochol • Allopregnanolone • Alphadolone • Alphaxolone • Eltanolone • Ganaxolone • Hydroxydione • Minaxolone • Org 20599 • Org 21465 • Tetrahydrodeoxycorticosterone; Nonbenzodiazepines: CL-218,872 • Eszopiclone • Indiplon • JM-1232 • Lirequinil • Necopidem • Pazinaclone • ROD-188 • Saripidem • Suproclone • Suriclone • SX-3228 • U-89843A • U-90042 • Zaleplon • Zolpidem • Zopiclone; Phenols: Fospropofol • Propofol; Piperidinediones: Glutethimide • Methyprylon • Pyrithyldione • Piperidione; Quinazolinones: Afloqualone • Cloroqualone • Diproqualone • Etaqualone • Mebroqualone • Mecloqualone • Methaqualone • Methylmethaqualone • Nitromethaqualone; Others: 2-Methyl-2-butanol • Acetophenone • Acetylglycinamide chloral hydrate • Bromide (Lithium bromide, Potassium bromide, Sodium bromide) • Centalun • Chloral hydrate • Chloralose • Chloralodol • Clomethiazole • Dichloralphenazone • Ethanol (Alcohol) • Ethchlorvynol • Etomidate • Gaboxadol • Loreclezole • Methylpentynol • Metomidate • Paraldehyde • Petrichloral • Sulfonmethane • Trichloroethanol • Triclofos • Valerenic acid (Valerian)

GABA_B Agonists
1,4-Butanediol • Aceburic acid • GABOB • GHB • GBL • GVL

H₁ Inverse agonists
Antihistamines: Captodiame • Cyproheptadine • Dimenhydrinate • Diphenhydramine • Doxylamine • Hydroxyzine • Methapyrilene • Pheniramine • Promethazine • Propiomazine; Others: Tricyclic antidepressants (Amitriptyline, Doxepin, Trimipramine, etc.) • Tetracyclic antidepressants (Mianserin, Mirtazapine, etc.) • Typical antipsychotics (Chlorpromazine, Thioridazine, etc.) • Atypical antipsychotics (Olanzapine, Quetiapine, Risperidone, etc.)

α₁-Adrenergic Antagonists
Mianserin • Niaprazine • Trazodone; Others: Tricyclic antidepressants (Amitriptyline, Doxepin, Trimipramine, etc.) • Typical antipsychotics (Chlorpromazine, Thioridazine, etc.) • Atypical antipsychotics (Olanzapine, Quetiapine, Risperidone, etc.)

α₂-Adrenergic Agonists
4-NEMD • Clonidine • Detomidine • Dexmedetomidine • Lofexidine • Medetomidine • Romifidine • Tizanidine • Xylazine

5-HT_2A Antagonists
Eplivanserin • Niaprazine • Pruvanserin • Trazodone • Volinanserin; Others: Tricyclic antidepressants (Amitriptyline, Doxepin, Trimipramine, etc.) • Tetracyclic antidepressants (Mianserin, Mirtazapine, etc.) • Typical antipsychotics (Chlorpromazine, Thioridazine, etc.) • Atypical antipsychotics (Olanzapine, Quetiapine, Risperidone, etc.)

Melatonin Agonists
Agomelatine • LY-156,735 • Melatonin • Ramelteon • Tasimelteon

Orexin Antagonists
Almorexant • SB-334,867 • SB-408,124 • SB-649,868 • Suvorexant • TCS-OX2-29

Others
Acecarbromal • Apronal • Bromisoval • Cannabidiol (Cannabis) • Carbromal • Embutramide • Evoxine • Fenadiazole • Gabapentin • Kavalactones (Kava) • Mephenoxalone • Opiates/Opioids (Hydrocodone, Morphine (Opium), etc.) • Passion flower • Scopolamine (Mandrake) • Valnoctamide

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Cloroqualone

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Systematic (IUPAC) name
3-(2,6-Dichlorophenyl)-2-ethyl-4-quinazolinone
Clinical data
Pregnancy cat.	?
Legal status	?
Routes	?
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half-life	?
Excretion	?
Identifiers
CAS number	25509-07-3
ATC code	None
PubChem	CID 63338
DrugBank	?
ChemSpider	57005^Y
UNII	172D4Q6LOW^Y
Chemical data
Formula	C₁₆H₁₂Cl₂N₂O
Mol. mass	319.185
SMILES	eMolecules & PubChem
InChI InChI=1S/C16H12Cl2N2O/c1-2-14-19-13-9-4-3-6-10(13)16(21)20(14)15-11(17)7-5-8-12(15)18/h3-9H,2H2,1H3^Y Key:SONHVLIDLXLSOL-UHFFFAOYSA-N^Y
Y(what is this?) (verify)

Academic Dictionaries and Encyclopedias

Wikipedia

Cloroqualone

See also

References

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