Methylmethaqualone

Methylmethaqualone

Systematic (IUPAC) name
3-(2,4-dimethylphenyl)-2-methylquinazolin-4(3H)-one
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	3244-75-5
ATC code	None
PubChem	CID 63382
ChemSpider	57045 Y
Chemical data
Formula	C17H16N2O
Mol. mass	264.322
SMILES	eMolecules & PubChem
InChI InChI=1S/C17H16N2O/c1-11-8-9-16(12(2)10-11)19-13(3)18-15-7-5-4-6-14(15)17(19)20/h4-10H,1-3H3 Y Key:MPMDMUROZIYIIM-UHFFFAOYSA-N Y
Y(what is this?)  (verify)

Methylmethaqualone (MMQ) is an analogue of methaqualone which has similar sedative and hypnotic properties to its parent compound, and is around the same potency. Methylmethaqualone differs from methaqualone by 4-methylation on the phenyl ring. It was made illegal in Germany in 1999 and listed by the DEA as a "drug of forensic interest" at about the same time, but little other information is available, it would appear that this compound was sold on the black market in Germany as a designer drug analogue of methaqualone.^[1][2]

Animal studies of methylmethaqualone have shown it to produce convulsions at only slightly above the effective sedative dose,^[3] and anecdotal reports from human users have confirmed that it can have a pro-convulsive effect, which could potentially make this compound particularly hazardous if taken in excessive doses.

References

1. ^ Klein RFX, Hays PA (January–June; 2003). "Detection and Analysis of Drugs of Forensic Interest, 1992 - 2001; A Literature Review." (pdf). Microgram Journal (DEA) 1 (1–2): 60. http://www.justice.gov/dea/programs/forensicsci/microgram/journal_v1/2003_1-2.pdf. 
2. ^ Angelos, S. A.; Lankin, D. C.; Meyers, J. A.; Raney, J. K. (1993). "The structural identification of a methyl analog of methaqualone via 2-dimensional NMR techniques". Journal of forensic sciences 38 (2): 455–465. PMID 8455002.  edit
3. ^ Boltze, K. H.; Dell, H. D.; Lehwald, H.; Lorenz, D.; Rueberg-Schweer, M. (1963). "Substituted 4-Quinazolinone Derivatives As Hypnotics and Anticonvulsants". Arzneimittel-Forschung 13: 688–701. PMID 14085923.  edit

This sedative-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Sedatives Convulsants Quinazolinones Sedative stubs Wikimedia Foundation. 2010. Игры ⚽ Нужна курсовая? Maguire Act of 1895 Harlan Cohen Look at other dictionaries: methylmethaqualone — noun A synthetic analogue of methaqualone with similar sedative and hypnotic properties …   Wiktionary Sodium thiopental — Systematic (IUPAC) name …   Wikipedia Methaqualone — Systematic (IUPAC) name 2 methyl 3 o tolyl 4(3H) quinazolinone; 3,4 dihydro 2 methyl 4 oxo 3 o tolylquinazoline; 2 methyl 3 (2 methylphenyl) 4 (3H) quinazolinone …   Wikipedia Propofol — Systematic (IUPAC) name 2,6 diisopropylphenol …   Wikipedia Designer drug — Not to be confused with Drug design. Designer drug is a term used to describe drugs that are created (or marketed, if they had already existed) to get around existing drug laws, usually by preparing analogs or derivatives of existing drugs by… …   Wikipedia Phenobarbital — Systematic (IUPAC) name 5 ethyl 5 phenylpyrimidine …   Wikipedia Secobarbital — Systematic (IUPAC) name 5 [(2R) pentan 2 yl] 5 prop 2 enyl 1,3 diazinane 2,4,6 trione Clinical data Trade names …   Wikipedia Pentobarbital — Systematic (IUPAC) name 5 Ethyl 5 (1 methylbutyl) 2,4,6(1H,3H,5H) pyrimidinetrione Clinical data AHFS/ …   Wikipedia Barbital — Systematic (IUPAC) name 5,5 diethylpyrimidine 2,4,6(1H,3H,5H) trione Clinical data MedlinePlus …   Wikipedia Methohexital — Systematic (IUPAC) name 5 hex 3 yn 2 yl 1 methyl 5 prop 2 enyl 1, 3 diazinane 2,4,6 trione Clinical data AHFS/Drugs.com …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”