- Butabarbital
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Butabarbital Systematic (IUPAC) name 5-butan-2-yl-5-ethyl-1,3-diazinane-2,4,6-trione Clinical data AHFS/Drugs.com Consumer Drug Information MedlinePlus a682417 Pregnancy cat. ? Legal status Schedule III (CA) Schedule III (US) Pharmacokinetic data Half-life 100 hours [1] Identifiers CAS number 125-40-6 ATC code None PubChem CID 2479 DrugBank DB00237 ChemSpider 2385 UNII P0078O25A9 KEGG D03180 ChEBI CHEBI:3228 ChEMBL CHEMBL449 Synonyms Butabarbital, Butisol Chemical data Formula C10H16N2O3 Mol. mass 212.246 g/mol SMILES eMolecules & PubChem (what is this?) (verify) Butabarbital (trade name Butisol) is a prescription barbiturate sleep aid. Butabarbital has a particularly fast onset of effects and short duration of action compared to other barbiturates, which makes it useful for certain applications such as treating severe insomnia and relieving anxiety before surgical procedures; however it is also relatively dangerous particularly when combined with alcohol, and so is now rarely used, although it is still prescribed in some Eastern European and South American countries. Its intermediate duration of action gives butabarbital an abuse potential slightly lower than secobarbital.
Butabarbital is also sold in combination with belladonna alkaloids under the brand name Butibel. The belladonna is added for antispasmodic effect. This product contains a low dose of butabarbital combined with a standardised mix of belladonna alkaloids and is used as an antispasmodic taken to relieve cramping and spasms of the stomach and intestines. They are used also to decrease the amount of acid formed in the stomach. Another similar product is Donnatal, which contains belladonna alkaloids combined with phenobarbital.
References
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