Antispasmodic

Antispasmodic

An antispasmodic (synonym: spasmolytic) is a drug or an herb that suppresses spasms. [eMedicineDictionary|Antispasmodic] cite web |url=http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/one/000006336.htm#000006336 |title=Dorlands Medical Dictionary:antispasmodic |format= |work= |accessdate=] These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.

Examples

Both dicyclomine and hyoscyamine are antispasmodic due to their anticholinergic action. Both of these drugs have general side effects and can worsen gastroesophageal reflux disease. [cite web |url=http://www.aafp.org/afp/20051215/2501.html |title=Treatment of Irritable Bowel Syndrome - December 15, 2005 -- American Family Physician |accessdate=2007-08-14 |format= |work=]

Peppermint oil has been traditionally used as an antispasmodic, and a review of studies on the topic found that it "could be efficacious for symptom relief in IBS"cite journal |author=Pittler MH, Ernst E |title=Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis |journal=Am. J. Gastroenterol. |volume=93 |issue=7 |pages=1131–5 |year=1998 |pmid=9672344|doi=10.1111/j.1572-0241.1998.00343.x] (as an antispasmodic) although more carefully controlled studies are needed. A later study showed it is an effective antispasmodic when test-applied topically to the intestine during endoscopy.cite journal |author=Hiki N, Kurosaka H, Tatsutomi Y, "et al" |title=Peppermint oil reduces gastric spasm during upper endoscopy: a randomized, double-blind, double-dummy controlled trial |journal=Gastrointest. Endosc. |volume=57 |issue=4 |pages=475–82 |year=2003 |pmid=12665756 |doi=10.1067/mge.2003.156]

The flower Liatris, also called blazing star, has also been used as an antispasmodic. Another old common name for this plant is Colic Root, alluding to its medicinal use as an antispasmodic for the intestines.

ee also

* Muscarinic antagonist
* Parasympatholytic

References

External links

*


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  • antispasmodic — ANTISPASMÓDIC, Ă, antispasmodici, ce, adj. Care combate spasmele; antispastic. – Din fr. antispasmodique. Trimis de ana zecheru, 29.02.2004. Sursa: DEX 98  ANTISPASMÓDIC s., adj. (farm.) antispastic, spasmolitic. (Atropina este un… …   Dicționar Român

  • antispasmodic — [an΄tīspaz mäd′ik, an΄tēspaz mäd′ik, an΄tispaz mäd′ik] adj. relieving or preventing spasms, esp. of smooth muscle n. an antispasmodic drug: See ANTISPASTIC …   English World dictionary

  • Antispasmodic — An ti*spas*mod ic, a. (Med.) Good against spasms. n. A medicine which prevents or allays spasms or convulsions. [1913 Webster] …   The Collaborative International Dictionary of English

  • Antispasmodic — 1) A medication that lowers the incidence of or prevents seizures. 2) A medication that lowers the incidence of or prevents muscle spasms. * * * 1. Preventing or alleviating muscle spasms (cramps). 2. An agent that quiets spasm. * * *… …   Medical dictionary

  • antispasmodic — adjective Date: 1763 capable of preventing or relieving spasms or convulsions • antispasmodic noun …   New Collegiate Dictionary

  • antispasmodic — adjective used to relieve spasm of involuntary muscle. noun an antispasmodic drug …   English new terms dictionary

  • antispasmodic — an•ti•spas•mod•ic [[t]ˌæn ti spæzˈmɒd ɪk, ˌæn taɪ [/t]] adj. 1) pha med used to control or prevent muscular spasms or convulsions 2) pha med an antispasmodic drug or substance • Etymology: 1680–85 …   From formal English to slang

  • antispasmodic — /ˌæntispæzˈmɒdɪk/ (say .anteespaz modik) adjective 1. checking spasms. –noun 2. an antispasmodic agent …  

  • antispasmodic — noun a drug used to relieve or prevent spasms (especially of the smooth muscles) • Syn: ↑spasmolytic, ↑antispasmodic agent • Hypernyms: ↑medicine, ↑medication, ↑medicament, ↑medicinal drug …   Useful english dictionary

  • antispasmodic agent — noun a drug used to relieve or prevent spasms (especially of the smooth muscles) • Syn: ↑antispasmodic, ↑spasmolytic • Hypernyms: ↑medicine, ↑medication, ↑medicament, ↑medicinal drug • …   Useful english dictionary

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