Chlorobutanol

Chlorobutanol
IUPAC name 1,1,1-Trichloro-2-methylpropan-2-ol
Other names 1,1,1-trichloro-2-methyl-2-propanol, chlorbutol, chloreton, chloretone, chlortran, trichloro-tert-butyl alcohol, 1,1,1-trichloro-tert-butyl alcohol, 2-(trichloromethyl)propan-2-ol, 1,1,1-trichloro-2-methyl-2-propanol, tert-Trichlorobutyl alcohol, trichloro-tert-butanol, trichlorisobutylalcohol, 2,2,2-trichloro-1,1-dimethylethanol
Identifiers
CAS number	57-15-8 Y
ChemSpider	13842993 Y
UNII	HM4YQM8WRC Y
KEGG	D01942 Y
Jmol-3D images	Image 1
SMILES ClC(Cl)(Cl)C(C)(C)O
InChI InChI=1S/C4H7Cl3O/c1-3(2,8)4(5,6)7/h8H,1-2H3 Y Key: OSASVXMJTNOKOY-UHFFFAOYSA-N Y InChI=1/C4H7Cl3O/c1-3(2,8)4(5,6)7/h8H,1-2H3 Key: OSASVXMJTNOKOY-UHFFFAOYAO
Properties
Molecular formula	C4H7Cl3O
Molar mass	175.5 g/mol
Appearance	White solid
Melting point	95–99 °C
Boiling point	167 °C
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Chlorobutanol, or trichloro-2-methyl-2-propanol, is a chemical preservative, sedative hypnotic and weak local anaesthetic similar in nature to chloral hydrate. It has antibacterial and antifungal properties. Chlorobutanol is typically used at a concentration of 0.5 % where it lends long term stability to multi-ingredient formulations.

Chemical synthesis

Chlorobutanol is formed by the simple nucleophilic addition of chloroform and acetone. The reaction is base driven by potassium or sodium hydroxide.

External links

• Chlorobutanol MSDS
• A04AD04