Casopitant

Casopitant

Drugbox
IUPAC_name = (2"S",4"S")-4-(4-Acetyl-1-piperazinyl)-"N"- [(1"R")-1- [3,5-bis(trifluoromethyl)phenyl] ethyl] -2-(4-fluoro-2-methylphenyl)-N-methyl-1-piperidinecarboxamide



width = 220
CAS_number =
CAS_supplemental =
ATC_prefix =
ATC_suffix =
PubChem = 23725089
DrugBank =
C=30|H=35|F=7|N=4|O=2
molecular_weight = 616.26 g/mol
smiles = CC1=C(C=CC(=C1)F) [C@@H] 2C [C@H] (CCN2C(=O)N(C) [C@H] (C)C3=CC(=CC(=C3) C(F)(F)F)C(F)(F)F)N4CCN(CC4)C(=O)C
bioavailability =
protein_bound =
metabolism =
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US =
pregnancy_category=
legal_AU =
legal_CA =
legal_UK =
legal_US =
routes_of_administration =

Casopitant (INN) is an neurokinin 1 receptor antagonist undergoing research for the treatment of chemotherapy-induced nausea and vomiting (CINV). [cite journal |author=Lohr L |title=Chemotherapy-induced nausea and vomiting |journal=Cancer J |volume=14 |issue=2 |pages=85–93 |year=2008 |pmid=18391612 |doi=10.1097/PPO.0b013e31816a0f07 |url=] It is developed by GlaxoSmithKline and is likely to be marketed in the US as Rezonic and in the EU as Zunrisa.

References


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • casopitant — noun A neurokinin receptor antagonist undergoing research for the treatment of chemotherapy induced nausea and vomiting …   Wiktionary

  • NK1 receptor antagonist — Neurokinin 1 (NK1) antagonists are a novel class of medications that possesses unique antidepressant,[1] anxiolytic,[2] and antiemetic properties. The discovery of neurokinin 1 (NK1) receptor antagonists was a turning point in the prevention of… …   Wikipedia

  • Tachykinin receptor 1 — Rendering based on PDB 2KS9 …   Wikipedia

  • Maropitant — Systematic (IUPAC) name (7R,8S) N [(5 tert Butyl 2 methoxyphenyl)methyl] 7 [di(phenyl)methyl] 1 azabicyclo[2.2.2]octan 8 amine Clinical data …   Wikipedia

  • АТХ код A04 — АТХ A «Препараты, влияющие на пищеварительный тракт и обмен веществ» АТХ код А01 Стоматологические препараты АТХ код A02 Препараты для лечения заболеваний, связанных с нарушением кислотности АТХ код A03 Препараты для лечения функциональных… …   Википедия

  • Scopolamine — Systematic (IUPAC) name (–) (S) 3 hydroxy 2 pheny …   Wikipedia

  • Adrenocorticotropic hormone — proopiomelanocortin (adrenocorticotropin/ beta lipotropin/ alpha melanocyte stimulating hormone/ beta melanocyte stimulating hormone/ beta endorphin) proopiomelanocortin derivatives POMC     …   Wikipedia

  • Tetrahydrocannabinol — THC redirects here. For other uses, see THC (disambiguation). Tetrahydrocannabinol (THC) …   Wikipedia

  • Antiemetic — An anti emetic is a drug that is effective against vomiting and nausea. Anti emetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics and chemotherapy directed against cancer. TOC Types… …   Wikipedia

  • Corticotropin-releasing hormone — PDB rendering based on 1go9 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”