Hexethal

Hexethal: Hexethal

Systematic (IUPAC) name

Sodium 5-ethyl-5-hexyl-4,6-dioxo-1H-pyrimidin-2-olate

Clinical data

Pregnancy cat. ?

Legal status ?

Identifiers

CAS number 144-00-3^Y

ATC code None

PubChem CID 8941

ChemSpider 8597^Y

Synonyms Sodium 5-ethyl-5-hexylbarbiturate, Ortol, Hebaral

Chemical data

Formula C₁₂H₁₉N₂Na O₃

Mol. mass 262.281 g/mol

SMILES eMolecules & PubChem

InChI

InChI=1S/C12H20N2O3.Na/c1-3-5-6-7-8-12(4-2)9(15)13-11(17)14-10(12)16;/h3-8H2,1-2H3,(H2,13,14,15,16,17);/q;+1/p-1^Y
Key:HXUAXLUDTCGASZ-UHFFFAOYSA-M^Y

Y(what is this?) (verify)

Hexethal (Ortol) is a barbiturate derivative invented in the 1940s. It has sedative and anticonvulsant properties, and was used primarily as an anaesthetic in veterinary medicine. ^[1]

Hexethal is considered similar in effects to pentobarbital, with a very fast onset of action but short duration of effects.

References

^ Butler, T. C. (1950). "The rate of penetration of barbituric acid derivatives into the brain". The Journal of pharmacology and experimental therapeutics 100 (2): 219–226. PMID 14784958. edit

v · d · eGABA_A receptor PAMs

Barbiturates
Allobarbital • Alphenal • Amobarbital • Aprobarbital • Barbexaclone • Barbital • Benzobarbital • Benzylbutylbarbiturate • Brallobarbital • Brophebarbital • Bucolome • Butabarbital • Butalbital • Butobarbital • Butallylonal • Carbubarb • Crotylbarbital • Cyclobarbital • Cyclopal • Enallylpropymal • Ethallobarbital • Febarbamate • Heptabarbital • Hexethal • Hexobarbital • Mephobarbital • Metharbital • Methohexital • Methylphenobarbital • Narcobarbital • Nealbarbital • Pentobarbital • Phenobarbital • Phetharbital • Primidone • Prazitone • Probarbital • Propallylonal • Proxibarbal • Proxibarbital • Reposal • Secbutabarbital • Secobarbital • Sigmodal • Spirobarbital • Talbutal • Thialbarbital • Thiamylal • Thiobarbital • Thiobutabarbital • Thiopental • Valofane • Vinbarbital • Vinylbital

Benzodiazepines
Adinazolam • Alprazolam • Arfendazam • Avizafone • Bentazepam • Bretazenil • Bromazepam • Brotizolam • Camazepam • Chlordiazepoxide • Ciclotizolam • Cinolazepam • Clazolam • Climazolam • Clobazam • Clonazepam • Clorazepate • Clotiazepam • Cloxazolam • Cyprazepam • Delorazepam • Diazepam • Doxefazepam • Elfazepam • Estazolam • Ethyl carfluzepate • Ethyl dirazepate • Ethyl loflazepate • Etizolam • Fletazepam • Fludiazepam • Flunitrazepam • Flurazepam • Flutazolam • Flutemazepam • Flutoprazepam • Fosazepam • Gidazepam • Girisopam • Halazepam • Haloxazolam • Iclazepam • Imidazenil • Ketazolam • Lofendazam • Lopirazepam • Lopirazepam • Loprazolam • Lorazepam • Lormetazepam • Meclonazepam • Medazepam • Menitrazepam • Metaclazepam • Mexazolam • Midazolam • Nerisopam • Nimetazepam • Nitrazepam • Nitrazepate • Nordazepam • Oxazepam • Oxazolam • Phenazepam • Pinazepam • Pivoxazepam • Prazepam • Premazepam • Proflazepam • QH-II-66 • Quazepam • Reclazepam • Remimazolam • Rilmazafone • Ripazepam • Ro48-6791 • SH-053-R-CH3-2′F • Sulazepam • Temazepam • Tetrazepam • Tofisopam • Triazolam • Triflubazam • Uldazepam • Zapizolam • Zolazepam • Zomebazam

Carbamates
Carisbamate • Carisoprodol • Emylcamate • Ethinamate • Febarbamate • Felbamate • Hexapropymate • Mebutamate • Meprobamate • Methocarbamol • Phenprobamate • Procymate • Styramate • Tybamate

Neuroactive steroids
Acebrochol • Allopregnanolone • Alphadolone • Alphaxolone • Ganaxolone • Hydroxydione • Minaxolone • Org 20599 • THDOC

Nonbenzodiazepines
β-Carbolines: Abecarnil • Gedocarnil • SL-651,498 • ZK-93423; Cyclopyrrolones: Eszopiclone • Pagoclone • Pazinaclone • Suproclone • Suriclone • Zopiclone; Imidazopyridines: Alpidem • Necopidem • Saripidem • Zolpidem; Pyrazolopyrimidines: Divaplon • Fasiplon • Indiplon • Lorediplon • Ocinaplon • Panadiplon • Taniplon • Zaleplon; Others: Adipiplon • CGS-8216 • CGS-9896 • CGS-13767 • CGS-20625 • CL-218,872 • CP-615,003 • ELB-139 • GBLD-345 • L-838,417 • NS-2664 • NS-2710 • NS-11394 • Pipequaline • ROD-188 • RWJ-51204 • SB-205,384 • SX-3228 • TP-003 • TPA-023 • TP-13 • U-89843A • U-90042 • Y-23684

Phenols
Fospropofol • Propofol • Thymol

Piperidinediones
Glutethimide • Methyprylon • Piperidione • Pyrithyldione

Pyrazolopyridines
Cartazolate • Etazolate • ICI-190,622 • Tracazolate

Quinazolinones
Afloqualone • Cloroqualone • Diproqualone • Etaqualone • Mebroqualone • Mecloqualone • Methaqualone • Methylmethaqualone

Volatiles/gases
2-Methyl-2-butanol • Acetone • Acetophenone • Acetylglycinamide chloral hydrate • Benzene • Butane • Butanol • Butylene • Centalun • Chloral • Chloral hydrate • Chlorobutanol • Chloroform • Cyclopropane • Desflurane • Dichloromethane • Diethyl ether • Enflurane • Ethanol (Alcohol) • Ethyl chloride • Ethylene • Gasoline • Halothane • Isoflurane • Kerosine • Menthol • Methanol • Methoxyflurane • Methoxypropane • Methylbutanol • Nitric oxide • Nitrogen • Nitrous oxide • Paraldehyde • Pentanol • Propane • Propanol • Propylene • Sevoflurane • Toluene • Trichloroethanol • Trichloroethylene • Vinyl ether • Xenon

Others
Bromide (Lithium bromide, Potassium bromide, Sodium bromide) • Chloralodol • Chloralose • Chlormezanone • Clomethiazole • DEABL • Ethchlorvynol • Etifoxine • Etomidate • GABA • Kavalactones (Kava) • Loreclezole • Methylpentynol • Metomidate • Petrichloral • Propanidid • Skullcap • Stiripentol • Sulfonmethane • Tetronal • Triclofos • Trional • Valeric acid, Valerenic acid (Valerian)

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Hexethal

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Systematic (IUPAC) name
Sodium 5-ethyl-5-hexyl-4,6-dioxo-1H-pyrimidin-2-olate
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	144-00-3^Y
ATC code	None
PubChem	CID 8941
ChemSpider	8597^Y
Synonyms	Sodium 5-ethyl-5-hexylbarbiturate, Ortol, Hebaral
Chemical data
Formula	C₁₂H₁₉N₂Na O₃
Mol. mass	262.281 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C12H20N2O3.Na/c1-3-5-6-7-8-12(4-2)9(15)13-11(17)14-10(12)16;/h3-8H2,1-2H3,(H2,13,14,15,16,17);/q;+1/p-1^Y Key:HXUAXLUDTCGASZ-UHFFFAOYSA-M^Y
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Hexethal

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