Evolution

Evolution
This article is about evolution in biology. For other uses, see Evolution (disambiguation).
For a generally accessible and less technical introduction to the topic, see Introduction to evolution.
Part of a series on
Evolutionary Biology
Evolutionary tree showing the divergence of modern species from their common ancestor
 
Evolutionary Biology Portal
Category • Related topics • Book
v · d · e

Evolution is any change across successive generations in the heritable characteristics of biological populations. Evolutionary processes give rise to diversity at every level of biological organisation, including species, individual organisms and molecules such as DNA and proteins.[1]

Life on Earth originated and then evolved from a universal common ancestor approximately 3.7 billion years ago. Repeated speciation and the divergence of life can be traced through shared sets of biochemical and morphological traits, or by shared DNA sequences. These homologous traits and sequences are more similar among species that share a more recent common ancestor, and can be used to reconstruct evolutionary histories, using both existing species and the fossil record. Existing patterns of biodiversity have been shaped both by speciation and by extinction.[2]

The theory of evolution by natural selection was formulated by Charles Darwin, who was the first to recognise natural selection as an important cause of evolution. Evolution by natural selection is a consequence of three widely accepted premises: 1) more offspring are produced than can possibly survive, 2) traits vary among individuals, leading to differential rates of survival and reproduction, and 3) trait differences are heritable.[3] Thus, when members of a population die, they are replaced by individuals that are not born from random parents. Instead, these new members are born from parents that are better adapted to the environment in which natural selection took place. This can cause the evolution of traits that are seemingly fitted for the functional roles they perform.[4] Natural selection is the only known cause of adaptation, but not the only known cause of evolution. Other, nonadaptive causes of evolution include mutation and genetic drift.[5]

In the early 20th century, genetics was integrated with Darwin's theory of evolution by natural selection through the discipline of population genetics. The importance of natural selection as a cause of evolution was accepted into other branches of biology. Moreover, previously held notions about evolution, such as orthogenesis and "progress" became obsolete.[6] Scientists continue to study evolution using both observational data and experiments in both the field and the laboratory. Biologists agree that descent with modification is one of the most reliably established facts in science.[7] Discoveries in evolutionary biology have made a significant impact not just within the traditional branches of biology, but also in other academic disciplines (e.g., anthropology and psychology) and on society at large.[8][9]

Contents

History of evolutionary thought

For more details on this topic, see History of evolutionary thought.

The proposal that one type of animal could descend from an animal of another type goes back to some of the first pre-Socratic Greek philosophers, such as Anaximander and Empedocles. In contrast to these materialistic views, Aristotle understood all natural things, not only living things, as being imperfect actualizations of different fixed natural possibilities, known as "forms", "ideas", or (in Latin translations) "species". This was part of his teleological understanding of nature in which all things have an intended role to play in a divine cosmic order. Variations of this idea became the standard understanding of the Middle Ages, and were integrated into Christian learning, but Aristotle did not demand that real types of animals corresponded one-for-one with exact metaphysical forms, and specifically gave examples of how new types of living things could come to be.

In the 17th century the new method of modern science rejected Aristotle's approach, and sought explanations of natural phenomena in terms of laws of nature which were the same for all visible things, and did not need to assume any fixed natural categories, nor any divine cosmic order. But this new approach was slow to take root in the biological sciences, which became the last bastion of the concept of fixed natural types. John Ray used one of the previously more general terms for fixed natural types, "species", to apply to animal and plant types, but unlike Aristotle he strictly identified each type of living thing as a species, and proposed that each species can be defined by the features that perpetuate themselves each generation. These species were designed by God, but showing differences caused by local conditions. The biological classification introduced by Carolus Linnaeus in 1735 also viewed species as fixed according to a divine plan.

Other naturalists of this time speculated on evolutionary change of species over time according to natural laws. Maupertuis wrote in 1751 of natural modifications occurring during reproduction and accumulating over many generations to produce new species. Buffon suggested that species could degenerate into different organisms, and Erasmus Darwin proposed that all warm-blooded animals could have descended from a single micro-organism (or "filament"). The first fully-fledged evolutionary scheme was Lamarck's "transmutation" theory of 1809 which envisaged spontaneous generation continually producing simple forms of life developed greater complexity in parallel lineages with an inherent progressive tendency, and that on a local level these lineages adapted to the environment by inheriting changes caused by use or disuse in parents.[10][11] (The latter process was later called Lamarckism.)[10][12][13][14] These ideas were condemned by establishment naturalists as speculation lacking empirical support. In particular Georges Cuvier insisted that species were unrelated and fixed, their similarities reflecting divine design for functional needs. In the meantime, Ray's ideas of benevolent design had been developed by William Paley into a natural theology which proposed complex adaptations as evidence of divine design, and was admired by Charles Darwin.[15][16][17]

In 1842 Charles Darwin penned his first sketch of what became On the Origin of Species.[18]

The critical break from the concept of fixed species in biology began with the theory of evolution by natural selection, which was formulated by Charles Darwin. Partly influenced by An Essay on the Principle of Population by Thomas Robert Malthus, Darwin noted that population growth would lead to a "struggle for existence" where favorable variations could prevail as others perished. Each generation, many offspring fail to survive to an age of reproduction because of limited resources. This could explain the diversity of animals and plants from a common ancestry through the working of natural laws working the same for all types of thing.[19][20][21][22] Darwin was developing his theory of "natural selection" from 1838 onwards until Alfred Russel Wallace sent him a similar theory in 1858. Both men presented their separate papers to the Linnean Society of London.[23] At the end of 1859, Darwin's publication of On the Origin of Species explained natural selection in detail and in a way that lead to an increasingly wide acceptance of Darwinian evolution. Thomas Henry Huxley applied Darwin's ideas to humans, using paleontology and comparative anatomy to provide strong evidence that humans and apes shared a common ancestry. Some were disturbed by this since it implied that humans did not have a special place in the universe.[24]

Precise mechanisms of reproductive heritability and the origin of new traits remained a mystery. Towards this end, Darwin developed his provisional theory of pangenesis.[25] In 1865 Gregor Mendel reported that traits were inherited in a predictable manner through the independent assortment and segregation of elements (later known as genes). Mendel's laws of inheritance eventually supplanted most of Darwin's pangenesis theory.[26] August Weismann made the important distinction between germ cells (sperm and eggs) and somatic cells of the body, demonstrating that heredity passes through the germ line only. Hugo de Vries connected Darwin's pangenesis theory to Wiesman's germ/soma cell distinction and proposed that Darwin's pangenes were concentrated in the cell nucleus and when expressed they could move into the cytoplasm to change the cells structure. De Vries was also one of the researchers who made Mendel's work well-known, believing that Mendelian traits corresponded to the transfer of heritable variations along the germline.[27] To explain how new variants originate, De Vries developed a mutation theory that led to a temporary rift between those who accepted Darwinian evolution and biometricians who allied with de Vries.[11][28][29] At the turn of the 20th century, pioneers in the field of population genetics, such as J.B.S. Haldane, Sewall Wright, and Ronald Fisher, set the foundations of evolution onto a robust statistical philosophy. The false contradiction between Darwin's theory, genetic mutations, and Mendelian inheritance was thus reconciled.[30]

In the 1920s and 1930s a modern evolutionary synthesis connected natural selection, mutation theory, and Mendelian inheritance into a unified theory that applied generally to any branch of biology. The modern synthesis was able to explain patterns observed across species in populations, through fossil transitions in palaeontology, and even complex cellular mechanisms in developmental biology.[11][31] The publication of the structure of DNA by James Watson and Francis Crick in 1953 demonstrated a physical basis for inheritance.[32] Molecular biology improved our understanding of the relationship between genotype and phenotype. Advancements were also made in phylogenetic systematics, mapping the transition of traits into a comparative and testable framework through the publication and use of evolutionary trees.[33][34] In 1973, evolutionary biologist Theodosius Dobzhansky penned that "nothing in biology makes sense except in the light of evolution", because it has brought to light the relations of what first seemed disjointed facts in natural history into a coherent explanatory body of knowledge that describes and predicts many observable facts about life on this planet.[35]

Since then, the modern synthesis has been further extended to explain biological phenomena across the full and integrative scale of the biological hierarchy, from genes to species. This extension has been dubbed "eco-evo-devo".[36][36][37][38]

Heredity

Further information: Introduction to genetics, Genetics, Heredity, and Norms of reaction
DNA structure. Bases are in the centre, surrounded by phosphate–sugar chains in a double helix.

Evolution in organisms occurs through changes in heritable traits – particular characteristics of an organism. In humans, for example, eye colour is an inherited characteristic and an individual might inherit the "brown-eye trait" from one of their parents.[39] Inherited traits are controlled by genes and the complete set of genes within an organism's genome is called its genotype.[40]

The complete set of observable traits that make up the structure and behaviour of an organism is called its phenotype. These traits come from the interaction of its genotype with the environment.[41] As a result, many aspects of an organism's phenotype are not inherited. For example, suntanned skin comes from the interaction between a person's genotype and sunlight; thus, suntans are not passed on to people's children. However, some people tan more easily than others, due to differences in their genotype; a striking example are people with the inherited trait of albinism, who do not tan at all and are very sensitive to sunburn.[42]

Heritable traits are known to be passed from one generation to the next via DNA, a molecule that encodes genetic information.[40] DNA is a long polymer composed of four types of bases. The sequence of bases along a particular DNA molecule specify the genetic information, in a manner similar to a sequence of letters spelling out a sentence. Before a cell divides, the DNA is copied, so that each of the resulting two cells will inherit the DNA sequence. Portions of a DNA molecule that specify a single functional unit are called genes; different genes have different sequences of bases. Within cells, the long strands of DNA form condensed structures called chromosomes. The specific location of a DNA sequence within a chromosome is known as a locus. If the DNA sequence at a locus varies between individuals, the different forms of this sequence are called alleles. DNA sequences can change through mutations, producing new alleles. If a mutation occurs within a gene, the new allele may affect the trait that the gene controls, altering the phenotype of the organism.[43] However, while this simple correspondence between an allele and a trait works in some cases, most traits are more complex and are controlled by multiple interacting genes.[44][45]

Recent findings have confirmed important examples of heritable changes that cannot be explained by changes to the sequence of nucleotides in the DNA. These phenomena are classed as epigenetic inheritance systems.[46] DNA methylation marking chromatin, self-sustaining metabolic loops, gene silencing by RNA interference and the three dimensional conformation of proteins (such as prions) are areas where epigenetic inheritance systems have been discovered at the organismic level.[47][48] Developmental biologists suggest that complex interactions in genetic networks and communication among cells can lead to heritable variations that may underlay some of the mechanics in developmental plasticity and canalization.[49] Heritability may also occur at even larger scales. For example, ecological inheritance through the process of niche construction is defined by the regular and repeated activities of organisms in their environment. This generates a legacy of effects that modify and feed back into the selection regime of subsequent generations. Descendants inherit genes plus environmental characteristics generated by the ecological actions of ancestors.[50] Other examples of heritability in evolution that are not under the direct control of genes include the inheritance of cultural traits and symbiogenesis.[51][52]

Variation

Black morph in peppered moth evolution
Further information: Genetic diversity and Population genetics

An individual organism's phenotype results from both its genotype and the influence from the environment it has lived in. A substantial part of the variation in phenotypes in a population is caused by the differences between their genotypes.[45] The modern evolutionary synthesis defines evolution as the change over time in this genetic variation. The frequency of one particular allele will become more or less prevalent relative to other forms of that gene. Variation disappears when a new allele reaches the point of fixation — when it either disappears from the population or replaces the ancestral allele entirely.[53]

Natural selection will only cause evolution if there is enough genetic variation in a population. Before the discovery of Mendelian genetics, one common hypothesis was blending inheritance. But with blending inheritance, genetic variance would be rapidly lost, making evolution by natural selection implausible. The Hardy-Weinberg principle provides the solution to how variation is maintained in a population with Mendelian inheritance. The frequencies of alleles (variations in a gene) will remain constant in the absence of selection, mutation, migration and genetic drift.[54]

Variation comes from mutations in genetic material, reshuffling of genes through sexual reproduction and migration between populations (gene flow). Despite the constant introduction of new variation through mutation and gene flow, most of the genome of a species is identical in all individuals of that species.[55] However, even relatively small differences in genotype can lead to dramatic differences in phenotype: for example, chimpanzees and humans differ in only about 5% of their genomes.[56]

Mutation

Further information: Mutation
Duplication of part of a chromosome.

Mutations are changes in the DNA sequence of a cell's genome. When mutations occur, they can either have no effect, alter the product of a gene, or prevent the gene from functioning. Based on studies in the fly Drosophila melanogaster, it has been suggested that if a mutation changes a protein produced by a gene, this will probably be harmful, with about 70% of these mutations having damaging effects, and the remainder being either neutral or weakly beneficial.[57]

Mutations can involve large sections of a chromosome becoming duplicated (usually by genetic recombination), which can introduce extra copies of a gene into a genome.[58] Extra copies of genes are a major source of the raw material needed for new genes to evolve.[59] This is important because most new genes evolve within gene families from pre-existing genes that share common ancestors.[60] For example, the human eye uses four genes to make structures that sense light: three for colour vision and one for night vision; all four are descended from a single ancestral gene.[61]

New genes can be generated from an ancestral gene when a duplicate copy mutates and acquires a new function. This process is easier once a gene has been duplicated because it increases the redundancy of the system; one gene in the pair can acquire a new function while the other copy continues to perform its original function.[62][63] Other types of mutations can even generate entirely new genes from previously noncoding DNA.[64][65]

The generation of new genes can also involve small parts of several genes being duplicated, with these fragments then recombining to form new combinations with new functions.[66][67] When new genes are assembled from shuffling pre-existing parts, domains act as modules with simple independent functions, which can be mixed together to produce new combinations with new and complex functions.[68] For example, polyketide synthases are large enzymes that make antibiotics; they contain up to one hundred independent domains that each catalyze one step in the overall process, like a step in an assembly line.[69]

Sex and recombination

Further information: Sexual reproduction, Genetic recombination, and Evolution of sexual reproduction

In asexual organisms, genes are inherited together, or linked, as they cannot mix with genes of other organisms during reproduction. In contrast, the offspring of sexual organisms contain random mixtures of their parents' chromosomes that are produced through independent assortment. In a related process called homologous recombination, sexual organisms exchange DNA between two matching chromosomes.[70] Recombination and reassortment do not alter allele frequencies, but instead change which alleles are associated with each other, producing offspring with new combinations of alleles.[71] Sex usually increases genetic variation and may increase the rate of evolution.[72][73]

Gene flow

Further information: Gene flow

Gene flow is the exchange of genes between populations and between species.[74] It can therefore be a source of variation that is new to a population or to a species. Gene flow can be caused by the movement of individuals between separate populations of organisms, as might be caused by the movement of mice between inland and coastal populations, or the movement of pollen between heavy metal tolerant and heavy metal sensitive populations of grasses.

Gene transfer between species includes the formation of hybrid organisms and horizontal gene transfer. Horizontal gene transfer is the transfer of genetic material from one organism to another organism that is not its offspring; this is most common among bacteria.[75] In medicine, this contributes to the spread of antibiotic resistance, as when one bacteria acquires resistance genes it can rapidly transfer them to other species.[76] Horizontal transfer of genes from bacteria to eukaryotes such as the yeast Saccharomyces cerevisiae and the adzuki bean beetle Callosobruchus chinensis has occurred.[77][78] An example of larger-scale transfers are the eukaryotic bdelloid rotifers, which have received a range of genes from bacteria, fungi and plants.[79] Viruses can also carry DNA between organisms, allowing transfer of genes even across biological domains.[80]

Large-scale gene transfer has also occurred between the ancestors of eukaryotic cells and bacteria, during the acquisition of chloroplasts and mitochondria. It is possible that eukaryotes themselves originated from horizontal gene transfers between bacteria and archaea.[81]

Mechanisms

Mutation followed by natural selection, results in a population with darker colouration.

From a Neo-Darwinian perspective, evolution occurs when there are changes in the frequencies of alleles within a population of interbreeding organisms.[54] For example, the allele for black colour in a population of moths becoming more common. Mechanisms that can lead to changes in allele frequencies include natural selection, genetic drift, genetic hitchhiking, mutation and gene flow.

Natural selection

Further information: Natural selection and Fitness (biology)

Evolution by means of natural selection is the process by which genetic mutations that enhance reproduction become and remain, more common in successive generations of a population. It has often been called a "self-evident" mechanism because it necessarily follows from three simple facts:

  • Heritable variation exists within populations of organisms.
  • Organisms produce more offspring than can survive.
  • These offspring vary in their ability to survive and reproduce.

These conditions produce competition between organisms for survival and reproduction. Consequently, organisms with traits that give them an advantage over their competitors pass these advantageous traits on, while traits that do not confer an advantage are not passed on to the next generation.[82]

The central concept of natural selection is the evolutionary fitness of an organism.[83] Fitness is measured by an organism's ability to survive and reproduce, which determines the size of its genetic contribution to the next generation.[83] However, fitness is not the same as the total number of offspring: instead fitness is indicated by the proportion of subsequent generations that carry an organism's genes.[84] For example, if an organism could survive well and reproduce rapidly, but its offspring were all too small and weak to survive, this organism would make little genetic contribution to future generations and would thus have low fitness.[83]

If an allele increases fitness more than the other alleles of that gene, then with each generation this allele will become more common within the population. These traits are said to be "selected for". Examples of traits that can increase fitness are enhanced survival and increased fecundity. Conversely, the lower fitness caused by having a less beneficial or deleterious allele results in this allele becoming rarer — they are "selected against".[85] Importantly, the fitness of an allele is not a fixed characteristic; if the environment changes, previously neutral or harmful traits may become beneficial and previously beneficial traits become harmful.[43] However, even if the direction of selection does reverse in this way, traits that were lost in the past may not re-evolve in an identical form (see Dollo's law).[86][87]

A chart showing three types of selection. 1. Disruptive selection 2. Stabilizing selection 3. Directional selection

Natural selection within a population for a trait that can vary across a range of values, such as height, can be categorised into three different types. The first is directional selection, which is a shift in the average value of a trait over time — for example, organisms slowly getting taller.[88] Secondly, disruptive selection is selection for extreme trait values and often results in two different values becoming most common, with selection against the average value. This would be when either short or tall organisms had an advantage, but not those of medium height. Finally, in stabilizing selection there is selection against extreme trait values on both ends, which causes a decrease in variance around the average value and less diversity.[82][89] This would, for example, cause organisms to slowly become all the same height.

A special case of natural selection is sexual selection, which is selection for any trait that increases mating success by increasing the attractiveness of an organism to potential mates.[90] Traits that evolved through sexual selection are particularly prominent in males of some animal species, despite traits such as cumbersome antlers, mating calls or bright colours that attract predators, decreasing the survival of individual males.[91] This survival disadvantage is balanced by higher reproductive success in males that show these hard to fake, sexually selected traits.[92]

Natural selection most generally makes nature the measure against which individuals and individual traits, are more or less likely to survive. "Nature" in this sense refers to an ecosystem, that is, a system in which organisms interact with every other element, physical as well as biological, in their local environment. Eugene Odum, a founder of ecology, defined an ecosystem as: "Any unit that includes all of the organisms...in a given area interacting with the physical environment so that a flow of energy leads to clearly defined trophic structure, biotic diversity and material cycles (ie: exchange of materials between living and nonliving parts) within the system."[93] Each population within an ecosystem occupies a distinct niche, or position, with distinct relationships to other parts of the system. These relationships involve the life history of the organism, its position in the food chain and its geographic range. This broad understanding of nature enables scientists to delineate specific forces which, together, comprise natural selection.

Natural selection can act at different levels of organisation, such as genes, cells, individual organisms, groups of organisms and species.[94][95][96] Selection can act at multiple levels simultaneously.[97] An example of selection occurring below the level of the individual organism are genes called transposons, which can replicate and spread throughout a genome.[98] Selection at a level above the individual, such as group selection, may allow the evolution of co-operation, as discussed below.[99]

Biased mutation

In addition to being a major source of variation, mutation may also function as a mechanism of evolution when there are different probabilities at the molecular level for different mutations to occur, a process known as mutation bias.[100] If two genotypes, for example one with the nucleotide G and another with the nucleotide A in the same position, have the same fitness, but mutation from G to A happens more often than mutation from A to G, then genotypes with A will tend to evolve.[101] Different insertion vs. deletion mutation biases in different taxa can lead to the evolution of different genome sizes.[102][103] Developmental or mutational biases have also been observed in morphological evolution.[104][105] For example, according to the phenotype-first theory of evolution, mutations can eventually cause the genetic assimilation of traits that were previously induced by the environment.[106][107]

Mutation bias effects are superimposed on other processes. If selection would favor either one out of two mutations, but there is no extra advantage to having both, then the mutation that occurs the most frequently is the one that is most likely to become fixed in a population.[108][109] Mutations leading to the loss of function of a gene are much more common than mutations that produce a new, fully functional gene. Most loss of function mutations are selected against. But when selection is weak, mutation bias towards loss of function can affect evolution.[110] For example, pigments are no longer useful when animals live in the darkness of caves, and tend to be lost.[111] This kind of loss of function can occur because of mutation bias, and/or because the function had a cost, and once the benefit of the function disappeared, natural selection leads to the loss. Loss of sporulation ability in a bacterium during laboratory evolution appears to have been caused by mutation bias, rather than natural selection against the cost of maintaining sporulation ability.[112] When there is no selection for loss of function, the speed at which loss evolves depends more on the mutation rate than it does on the effective population size,[113] indicating that it is driven more by mutation bias than by genetic drift.

Genetic drift

Further information: Genetic drift and Effective population size
Simulation of genetic drift of 20 unlinked alleles in populations of 10 (top) and 100 (bottom). Drift to fixation is more rapid in the smaller population.

Genetic drift is the change in allele frequency from one generation to the next that occurs because alleles are subject to sampling error.[114] As a result, when selective forces are absent or relatively weak, allele frequencies tend to "drift" upward or downward randomly (in a random walk). This drift halts when an allele eventually becomes fixed, either by disappearing from the population, or replacing the other alleles entirely. Genetic drift may therefore eliminate some alleles from a population due to chance alone. Even in the absence of selective forces, genetic drift can cause two separate populations that began with the same genetic structure to drift apart into two divergent populations with different sets of alleles.[115]

It is usually difficult to measure the relative importance of selection and neutral processes, including drift.[116] The comparative importance of adaptive and non-adaptive forces in driving evolutionary change is an area of current research.[117]

The neutral theory of molecular evolution proposed that most evolutionary changes are the result of the fixation of neutral mutations by genetic drift.[5] Hence, in this model, most genetic changes in a population are the result of constant mutation pressure and genetic drift.[118] This form of the neutral theory is now largely abandoned, since it does not seem to fit the genetic variation seen in nature.[119][120] However, a more recent and better-supported version of this model is the nearly neutral theory, where a mutation that would be neutral in a small population is not necessarily neutral in a large population.[82] Other alternative theories propose that genetic drift is dwarfed by other stochastic forces in evolution, such as genetic hitchhiking, also known as genetic draft.[114][121][122]

The time for a neutral allele to become fixed by genetic drift depends on population size, with fixation occurring more rapidly in smaller populations.[123] The number of individuals in a population is not critical, but instead a measure known as the effective population size.[124] The effective population is usually smaller than the total population since it takes into account factors such as the level of inbreeding and the stage of the lifecycle in which the population is the smallest.[124] The effective population size may not be the same for every gene in the same population.[125]

Genetic hitchhiking

Further information: Genetic hitchhiking, Hill-Robertson effect, Selective sweep, and Genetic drift

Recombination allows alleles on the same strand of DNA to become separated. However, the rate of recombination is low (approximately two events per chromosome per generation). As a result, genes close together on a chromosome may not always be shuffled away from each other and genes that are close together tend to be inherited together, a phenomenon known as linkage.[126] This tendency is measured by finding how often two alleles occur together on a single chromosome compared to expectations, which is called their linkage disequilibrium. A set of alleles that is usually inherited in a group is called a haplotype. This can be important when one allele in a particular haplotype is strongly beneficial: natural selection can drive a selective sweep that will also cause the other alleles in the haplotype to become more common in the population; this effect is called genetic hitchhiking or genetic draft.[127] Genetic draft caused by the fact that some neutral genes are genetically linked to others that are under selection can be partially captured by an appropriate effective population size.[121]

Gene flow

Further information: Gene flow, Hybrid (biology), and Horizontal gene transfer

Gene flow is the exchange of genes between populations and between species.[74] The presence or absence of gene flow fundamentally changes the course of evolution. Due to the complexity of organisms, any two completely isolated populations will eventually evolve genetic incompatibilities through neutral processes, as in the Bateson-Dobzhansky-Muller model, even if both populations remain essentially identical in terms of their adaptation to the environment.

If genetic differentiation between populations develops, gene flow between populations can introduce traits or alleles which are disadvantageous in the local population and this may lead to organism within these populations to evolve mechanisms that prevent mating with genetically distant populations, eventually resulting in the appearance of new species. Thus, exchange of genetic information between individuals is fundamentally important for the development of the biological species concept (BSC).

During the development of the modern synthesis, Sewall Wright's developed his shifting balance theory that gene flow between partially isolated populations was an important aspect of adaptive evolution.[128] However, recently there has been substantial criticism of the importance of the shifting balance theory.[129]

Outcomes

Evolution influences every aspect of the form and behaviour of organisms. Most prominent are the specific behavioural and physical adaptations that are the outcome of natural selection. These adaptations increase fitness by aiding activities such as finding food, avoiding predators or attracting mates. Organisms can also respond to selection by co-operating with each other, usually by aiding their relatives or engaging in mutually beneficial symbiosis. In the longer term, evolution produces new species through splitting ancestral populations of organisms into new groups that cannot or will not interbreed.

These outcomes of evolution are sometimes divided into macroevolution, which is evolution that occurs at or above the level of species, such as extinction and speciation and microevolution, which is smaller evolutionary changes, such as adaptations, within a species or population.[130] In general, macroevolution is regarded as the outcome of long periods of microevolution.[131] Thus, the distinction between micro- and macroevolution is not a fundamental one – the difference is simply the time involved.[132] However, in macroevolution, the traits of the entire species may be important. For instance, a large amount of variation among individuals allows a species to rapidly adapt to new habitats, lessening the chance of it going extinct, while a wide geographic range increases the chance of speciation, by making it more likely that part of the population will become isolated. In this sense, microevolution and macroevolution might involve selection at different levels – with microevolution acting on genes and organisms, versus macroevolutionary processes such as species selection acting on entire species and affecting their rates of speciation and extinction.[133][134][135]

A common misconception is that evolution has goals or long-term plans; realistically however, evolution has no long-term goal and does not necessarily produce greater complexity.[136][137] Although complex species have evolved, they occur as a side effect of the overall number of organisms increasing and simple forms of life still remain more common in the biosphere.[138] For example, the overwhelming majority of species are microscopic prokaryotes, which form about half the world's biomass despite their small size,[139] and constitute the vast majority of Earth's biodiversity.[140] Simple organisms have therefore been the dominant form of life on Earth throughout its history and continue to be the main form of life up to the present day, with complex life only appearing more diverse because it is more noticeable.[141] Indeed, the evolution of microorganisms is particularly important to modern evolutionary research, since their rapid reproduction allows the study of experimental evolution and the observation of evolution and adaptation in real time.[142][143]

Adaptation

For more details on this topic, see Adaptation.

Adaptation is the process that makes organisms better suited to their habitat.[144][145] Also, the term adaptation may refer to a trait that is important for an organism's survival. For example, the adaptation of horses' teeth to the grinding of grass. By using the term adaptation for the evolutionary process and adaptive trait for the product (the bodily part or function), the two senses of the word may be distinguished. Adaptations are produced by natural selection.[146] The following definitions are due to Theodosius Dobzhansky.

  1. Adaptation is the evolutionary process whereby an organism becomes better able to live in its habitat or habitats.[147]
  2. Adaptedness is the state of being adapted: the degree to which an organism is able to live and reproduce in a given set of habitats.[148]
  3. An adaptive trait is an aspect of the developmental pattern of the organism which enables or enhances the probability of that organism surviving and reproducing.[149]

Adaptation may cause either the gain of a new feature, or the loss of an ancestral feature. An example that shows both types of change is bacterial adaptation to antibiotic selection, with genetic changes causing antibiotic resistance by both modifying the target of the drug, or increasing the activity of transporters that pump the drug out of the cell.[150] Other striking examples are the bacteria Escherichia coli evolving the ability to use citric acid as a nutrient in a long-term laboratory experiment,[151] Flavobacterium evolving a novel enzyme that allows these bacteria to grow on the by-products of nylon manufacturing,[152][153] and the soil bacterium Sphingobium evolving an entirely new metabolic pathway that degrades the synthetic pesticide pentachlorophenol.[154][155] An interesting but still controversial idea is that some adaptations might increase the ability of organisms to generate genetic diversity and adapt by natural selection (increasing organisms' evolvability).[156][157][158][159]

A baleen whale skeleton, a and b label flipper bones, which were adapted from front leg bones: while c indicates vestigial leg bones, suggesting an adaptation from land to sea.[160]

Adaptation occurs through the gradual modification of existing structures. Consequently, structures with similar internal organisation may have different functions in related organisms. This is the result of a single ancestral structure being adapted to function in different ways. The bones within bat wings, for example, are very similar to those in mice feet and primate hands, due to the descent of all these structures from a common mammalian ancestor.[161] However, since all living organisms are related to some extent,[162] even organs that appear to have little or no structural similarity, such as arthropod, squid and vertebrate eyes, or the limbs and wings of arthropods and vertebrates, can depend on a common set of homologous genes that control their assembly and function; this is called deep homology.[163][164]

During evolution, some structures may lose their original function and become vestigial structures.[165] Such structures may have little or no function in a current species, yet have a clear function in ancestral species, or other closely related species. Examples include pseudogenes,[166] the non-functional remains of eyes in blind cave-dwelling fish,[167] wings in flightless birds,[168] and the presence of hip bones in whales and snakes.[160] Examples of vestigial structures in humans include wisdom teeth,[169] the coccyx,[165] the vermiform appendix,[165] and other behavioural vestiges such as goose bumps[170][171] and primitive reflexes.[172][173][174]

However, many traits that appear to be simple adaptations are in fact exaptations: structures originally adapted for one function, but which coincidentally became somewhat useful for some other function in the process.[175] One example is the African lizard Holaspis guentheri, which developed an extremely flat head for hiding in crevices, as can be seen by looking at its near relatives. However, in this species, the head has become so flattened that it assists in gliding from tree to tree—an exaptation.[175] Within cells, molecular machines such as the bacterial flagella[176] and protein sorting machinery[177] evolved by the recruitment of several pre-existing proteins that previously had different functions.[130] Another example is the recruitment of enzymes from glycolysis and xenobiotic metabolism to serve as structural proteins called crystallins within the lenses of organisms' eyes.[178][179]

A critical principle of ecology is that of competitive exclusion: no two species can occupy the same niche in the same environment for a long time.[180] Consequently, natural selection will tend to force species to adapt to different ecological niches. This may mean that, for example, two species of cichlid fish adapt to live in different habitats, which will minimise the competition between them for food.[181]

An area of current investigation in evolutionary developmental biology is the developmental basis of adaptations and exaptations.[182] This research addresses the origin and evolution of embryonic development and how modifications of development and developmental processes produce novel features.[183] These studies have shown that evolution can alter development to produce new structures, such as embryonic bone structures that develop into the jaw in other animals instead forming part of the middle ear in mammals.[184] It is also possible for structures that have been lost in evolution to reappear due to changes in developmental genes, such as a mutation in chickens causing embryos to grow teeth similar to those of crocodiles.[185] It is now becoming clear that most alterations in the form of organisms are due to changes in a small set of conserved genes.[186]

Co-evolution

Common Garter Snake (Thamnophis sirtalis sirtalis) which has evolved resistance to tetrodotoxin in its amphibian prey.
Further information: Co-evolution

Interactions between organisms can produce both conflict and co-operation. When the interaction is between pairs of species, such as a pathogen and a host, or a predator and its prey, these species can develop matched sets of adaptations. Here, the evolution of one species causes adaptations in a second species. These changes in the second species then, in turn, cause new adaptations in the first species. This cycle of selection and response is called co-evolution.[187] An example is the production of tetrodotoxin in the rough-skinned newt and the evolution of tetrodotoxin resistance in its predator, the common garter snake. In this predator-prey pair, an evolutionary arms race has produced high levels of toxin in the newt and correspondingly high levels of toxin resistance in the snake.[188]

Co-operation

Further information: Co-operation (evolution)

Not all co-evolved interactions between species involve conflict.[189] Many cases of mutually beneficial interactions have evolved. For instance, an extreme cooperation exists between plants and the mycorrhizal fungi that grow on their roots and aid the plant in absorbing nutrients from the soil.[190] This is a reciprocal relationship as the plants provide the fungi with sugars from photosynthesis. Here, the fungi actually grow inside plant cells, allowing them to exchange nutrients with their hosts, while sending signals that suppress the plant immune system.[191]

Coalitions between organisms of the same species have also evolved. An extreme case is the eusociality found in social insects, such as bees, termites and ants, where sterile insects feed and guard the small number of organisms in a colony that are able to reproduce. On an even smaller scale, the somatic cells that make up the body of an animal limit their reproduction so they can maintain a stable organism, which then supports a small number of the animal's germ cells to produce offspring. Here, somatic cells respond to specific signals that instruct them whether to grow, remain as they are, or die. If cells ignore these signals and multiply inappropriately, their uncontrolled growth causes cancer.[192]

Such cooperation within species may have evolved through the process of kin selection, which is where one organism acts to help raise a relative's offspring.[193] This activity is selected for because if the helping individual contains alleles which promote the helping activity, it is likely that its kin will also contain these alleles and thus those alleles will be passed on.[194] Other processes that may promote cooperation include group selection, where cooperation provides benefits to a group of organisms.[195]

Speciation

Further information: Speciation
The four mechanisms of speciation.

Speciation is the process where a species diverges into two or more descendant species.[196]

There are multiple ways to define the concept of "species". The choice of definition is dependent on the particularities of the species concerned.[197] For example, some species concepts apply more readily toward sexually reproducing organisms while others lend themselves better toward asexual organisms. Despite the diversity of various species concepts, these various concepts can be placed into one of three broad philosophical approaches: interbreeding, ecological and phylogenetic.[198] The biological species concept (BSC) is a classic example of the interbreeding approach. Defined by Ernst Mayr in 1942, the BSC states that "species are groups of actually or potentially interbreeding natural populations, which are reproductively isolated from other such groups"[199]:120. Despite its wide and long-term use, the BSC like others is not without controversy, for example because these concepts cannot be applied to prokaryotes,[200] and this is called the species problem.[197] Some researchers have attempted a unifying monistic definition of species, while others adopt a pluralistic approach and suggest that there may be a different ways to logically interpret the definition of a species.[197][198] "

Barriers to reproduction between two diverging sexual populations are required for the populations to become new species. Gene flow may slow this process by spreading the new genetic variants also to the other populations. Depending on how far two species have diverged since their most recent common ancestor, it may still be possible for them to produce offspring, as with horses and donkeys mating to produce mules.[201] Such hybrids are generally infertile. In this case, closely related species may regularly interbreed, but hybrids will be selected against and the species will remain distinct. However, viable hybrids are occasionally formed and these new species can either have properties intermediate between their parent species, or possess a totally new phenotype.[202] The importance of hybridisation in producing new species of animals is unclear, although cases have been seen in many types of animals,[203] with the gray tree frog being a particularly well-studied example.[204]

Speciation has been observed multiple times under both controlled laboratory conditions and in nature.[205] In sexually reproducing organisms, speciation results from reproductive isolation followed by genealogical divergence. There are four mechanisms for speciation. The most common in animals is allopatric speciation, which occurs in populations initially isolated geographically, such as by habitat fragmentation or migration. Selection under these conditions can produce very rapid changes in the appearance and behaviour of organisms.[206][207] As selection and drift act independently on populations isolated from the rest of their species, separation may eventually produce organisms that cannot interbreed.[208]

The second mechanism of speciation is peripatric speciation, which occurs when small populations of organisms become isolated in a new environment. This differs from allopatric speciation in that the isolated populations are numerically much smaller than the parental population. Here, the founder effect causes rapid speciation after an increase in inbreeding increases selection on homozygotes, leading to rapid genetic change.[209]

The third mechanism of speciation is parapatric speciation. This is similar to peripatric speciation in that a small population enters a new habitat, but differs in that there is no physical separation between these two populations. Instead, speciation results from the evolution of mechanisms that reduce gene flow between the two populations.[196] Generally this occurs when there has been a drastic change in the environment within the parental species' habitat. One example is the grass Anthoxanthum odoratum, which can undergo parapatric speciation in response to localised metal pollution from mines.[210] Here, plants evolve that have resistance to high levels of metals in the soil. Selection against interbreeding with the metal-sensitive parental population produced a gradual change in the flowering time of the metal-resistant plants, which eventually produced complete reproductive isolation. Selection against hybrids between the two populations may cause reinforcement, which is the evolution of traits that promote mating within a species, as well as character displacement, which is when two species become more distinct in appearance.[211]

Geographical isolation of finches on the Galápagos Islands produced over a dozen new species.

Finally, in sympatric speciation species diverge without geographic isolation or changes in habitat. This form is rare since even a small amount of gene flow may remove genetic differences between parts of a population.[212] Generally, sympatric speciation in animals requires the evolution of both genetic differences and non-random mating, to allow reproductive isolation to evolve.[213]

One type of sympatric speciation involves cross-breeding of two related species to produce a new hybrid species. This is not common in animals as animal hybrids are usually sterile. This is because during meiosis the homologous chromosomes from each parent are from different species and cannot successfully pair. However, it is more common in plants because plants often double their number of chromosomes, to form polyploids.[214] This allows the chromosomes from each parental species to form matching pairs during meiosis, since each parent's chromosomes are represented by a pair already.[215] An example of such a speciation event is when the plant species Arabidopsis thaliana and Arabidopsis arenosa cross-bred to give the new species Arabidopsis suecica.[216] This happened about 20,000 years ago,[217] and the speciation process has been repeated in the laboratory, which allows the study of the genetic mechanisms involved in this process.[218] Indeed, chromosome doubling within a species may be a common cause of reproductive isolation, as half the doubled chromosomes will be unmatched when breeding with undoubled organisms.[219]

Speciation events are important in the theory of punctuated equilibrium, which accounts for the pattern in the fossil record of short "bursts" of evolution interspersed with relatively long periods of stasis, where species remain relatively unchanged.[220] In this theory, speciation and rapid evolution are linked, with natural selection and genetic drift acting most strongly on organisms undergoing speciation in novel habitats or small populations. As a result, the periods of stasis in the fossil record correspond to the parental population and the organisms undergoing speciation and rapid evolution are found in small populations or geographically restricted habitats and therefore rarely being preserved as fossils.[221]

Extinction

Further information: Extinction
Tyrannosaurus rex. Non-avian dinosaurs died out in the Cretaceous–Tertiary extinction event at the end of the Cretaceous period.

Extinction is the disappearance of an entire species. Extinction is not an unusual event, as species regularly appear through speciation and disappear through extinction.[222] Nearly all animal and plant species that have lived on Earth are now extinct,[223] and extinction appears to be the ultimate fate of all species.[224] These extinctions have happened continuously throughout the history of life, although the rate of extinction spikes in occasional mass extinction events.[225] The Cretaceous–Tertiary extinction event, during which the non-avian dinosaurs went extinct, is the most well-known, but the earlier Permian–Triassic extinction event was even more severe, with approximately 96% of species driven to extinction.[225] The Holocene extinction event is an ongoing mass extinction associated with humanity's expansion across the globe over the past few thousand years. Present-day extinction rates are 100–1000 times greater than the background rate and up to 30% of species may be extinct by the mid 21st century.[226] Human activities are now the primary cause of the ongoing extinction event;[227] global warming may further accelerate it in the future.[228]

The role of extinction in evolution is not very well understood and may depend on which type of extinction is considered.[225] The causes of the continuous "low-level" extinction events, which form the majority of extinctions, may be the result of competition between species for limited resources (competitive exclusion).[36] If one species can out-compete another, this could produce species selection, with the fitter species surviving and the other species being driven to extinction.[95] The intermittent mass extinctions are also important, but instead of acting as a selective force, they drastically reduce diversity in a nonspecific manner and promote bursts of rapid evolution and speciation in survivors.[229]

Evolutionary history of life

Main article: Evolutionary history of life
See also: Timeline of evolution and Timeline of human evolution

Origin of life

Further information: Abiogenesis and RNA world hypothesis

Highly energetic chemistry is believed to have produced a self-replicating molecule around 4 billion years ago and half a billion years later the last common ancestor of all life existed.[230] The current scientific consensus is that the complex biochemistry that makes up life came from simpler chemical reactions.[231] The beginning of life may have included self-replicating molecules such as RNA,[232] and the assembly of simple cells.[233]

Common descent

Further information: Common descent, Evidence of common descent, and Homology (biology)
The hominoids are descendants of a common ancestor.

All organisms on Earth are descended from a common ancestor or ancestral gene pool.[162][234] Current species are a stage in the process of evolution, with their diversity the product of a long series of speciation and extinction events.[235] The common descent of organisms was first deduced from four simple facts about organisms: First, they have geographic distributions that cannot be explained by local adaptation. Second, the diversity of life is not a set of completely unique organisms, but organisms that share morphological similarities. Third, vestigial traits with no clear purpose resemble functional ancestral traits and finally, that organisms can be classified using these similarities into a hierarchy of nested groups – similar to a family tree.[236] However, modern research has suggested that, due to horizontal gene transfer, this "tree of life" may be more complicated than a simple branching tree since some genes have spread independently between distantly related species.[237][238]

Past species have also left records of their evolutionary history. Fossils, along with the comparative anatomy of present-day organisms, constitute the morphological, or anatomical, record.[239] By comparing the anatomies of both modern and extinct species, paleontologists can infer the lineages of those species. However, this approach is most successful for organisms that had hard body parts, such as shells, bones or teeth. Further, as prokaryotes such as bacteria and archaea share a limited set of common morphologies, their fossils do not provide information on their ancestry.

More recently, evidence for common descent has come from the study of biochemical similarities between organisms. For example, all living cells use the same basic set of nucleotides and amino acids.[240] The development of molecular genetics has revealed the record of evolution left in organisms' genomes: dating when species diverged through the molecular clock produced by mutations.[241] For example, these DNA sequence comparisons have revealed that humans and chimpanzees share 96% of their genomes and analyzing the few areas where they differ helps shed light on when the common ancestor of these species existed.[242]

Evolution of life

Main articles: Evolutionary history of life and Timeline of evolution
Euryarchaeota Nanoarchaeota Crenarchaeota Protozoa Algae Plantae Slime molds Animal Fungus Gram-positive bacteria Chlamydiae Chloroflexi Actinobacteria Planctomycetes Spirochaetes Fusobacteria Cyanobacteria Thermophiles Acidobacteria Proteobacteria
Evolutionary tree showing the divergence of modern species from their common ancestor in the centre.[243] The three domains are coloured, with bacteria blue, archaea green and eukaryotes red.

Prokaryotes inhabited the Earth from approximately 3–4 billion years ago.[244][245] No obvious changes in morphology or cellular organisation occurred in these organisms over the next few billion years.[246]

The eukaryotic cells emerged between 1.6 – 2.7 billion years ago. The next major change in cell structure came when bacteria were engulfed by eukaryotic cells, in a cooperative association called endosymbiosis.[247][248] The engulfed bacteria and the host cell then underwent co-evolution, with the bacteria evolving into either mitochondria or hydrogenosomes.[249] Another engulfment of cyanobacterial-like organisms led to the formation of chloroplasts in algae and plants.[250]

The history of life was that of the unicellular eukaryotes, prokaryotes and archaea until about 610 million years ago when multicellular organisms began to appear in the oceans in the Ediacaran period.[244][251] The evolution of multicellularity occurred in multiple independent events, in organisms as diverse as sponges, brown algae, cyanobacteria, slime moulds and myxobacteria.[252]

Soon after the emergence of these first multicellular organisms, a remarkable amount of biological diversity appeared over approximately 10 million years, in an event called the Cambrian explosion. Here, the majority of types of modern animals appeared in the fossil record, as well as unique lineages that subsequently became extinct.[253] Various triggers for the Cambrian explosion have been proposed, including the accumulation of oxygen in the atmosphere from photosynthesis.[254]

About 500 million years ago, plants and fungi colonised the land and were soon followed by arthropods and other animals.[255] Insects were particularly successful and even today make up the majority of animal species.[256] Amphibians first appeared around 364 million years ago, followed by early amniotes, then birds around 155 million years ago (both from "reptile"-like lineages), mammals around 129 million years ago, homininae around 10 million years ago and modern humans around 0.25 million years ago.[257][258][259] However, despite the evolution of these large animals, smaller organisms similar to the types that evolved early in this process continue to be highly successful and dominate the Earth, with the majority of both biomass and species being prokaryotes.[140]

Applications

Further information: Applications of evolution, Artificial selection, and Evolutionary computation

Concepts and models used in evolutionary biology, in particular natural selection, have many applications.[260]

Artificial selection is the intentional selection of traits in a population of organisms. This has been used for thousands of years in the domestication of plants and animals.[261] More recently, such selection has become a vital part of genetic engineering, with selectable markers such as antibiotic resistance genes being used to manipulate DNA. In repeated rounds of mutation and selection proteins with valuable properties have evolved, for example modified enzymes and new antibodies, in a process called directed evolution.[262]

Understanding the changes that have occurred during organism's evolution can reveal the genes needed to construct parts of the body, genes which may be involved in human genetic disorders.[263] For example, the mexican tetra is an albino cavefish that lost its eyesight during evolution. Breeding together different populations of this blind fish produced some offspring with functional eyes, since different mutations had occurred in the isolated populations that had evolved in different caves.[264] This helped identify genes required for vision and pigmentation.[265]

In computer science, simulations of evolution using evolutionary algorithms and artificial life started in the 1960s and was extended with simulation of artificial selection.[266] Artificial evolution became a widely recognised optimisation method as a result of the work of Ingo Rechenberg in the 1960s. He used evolution strategies to solve complex engineering problems.[267] Genetic algorithms in particular became popular through the writing of John Holland.[268] Practical applications also include automatic evolution of computer programs.[269] Evolutionary algorithms are now used to solve multi-dimensional problems more efficiently than software produced by human designers and also to optimise the design of systems.[270]

Social and cultural responses

Further information: Social effect of evolutionary theory and Objections to evolution
As evolution became widely accepted in the 1870s, caricatures of Charles Darwin with an ape or monkey body symbolised evolution.[271]

In the 19th century, particularly after the publication of On the Origin of Species in 1859, the idea that life had evolved was an active source of academic debate centred on the philosophical, social and religious implications of evolution. Nowadays, the modern evolutionary synthesis is accepted by a vast majority of scientists.[36] However, evolution remains a contentious concept for some theists.[272]

While various religions and denominations have reconciled their beliefs with evolution through concepts such as theistic evolution, there are creationists who believe that evolution is contradicted by the creation myths found in their religions and who raise various objections to evolution.[130][273][274] As had been demonstrated by responses to the publication of Vestiges of the Natural History of Creation in 1844, the most controversial aspect of evolutionary biology is the implication of human evolution that humans share common ancestry with apes and that the mental and moral faculties of humanity have the same types of natural causes as other inherited traits in animals.[275] In some countries, notably the United States, these tensions between science and religion have fuelled the current creation-evolution controversy, a religious conflict focusing on politics and public education.[276] While other scientific fields such as cosmology[277] and Earth science[278] also conflict with literal interpretations of many religious texts, evolutionary biology experiences significantly more opposition from religious literalists.

The teaching of evolution in American secondary school biology classes was uncommon in most of the first half of the 20th century. The Scopes Trial decision of 1925 caused the subject to become very rare in American secondary biology textbooks for a generation, but it was gradually re-introduced about a generation later and legally protected with the 1968 Epperson v. Arkansas decision. Since then, the competing religious belief of creationism was legally disallowed in secondary school curricula in various decisions in the 1970s and 1980s, but it returned in the form of intelligent design, to be excluded once again in the 2005 Kitzmiller v. Dover Area School District case.[279]

See also

References

  1. ^ Hall, B. K.; Hallgrímsson, B., eds (2008). Strickberger's Evolution (4th ed.). Jones & Bartlett. pp. 762. ISBN 0763700665. http://www.jblearning.com/catalog/9780763700669/. 
  2. ^ Cracraft, J.; Donoghue, M. J., eds (2005). Assembling the tree of life. Oxford University Press. pp. 592. ISBN 0195172345. http://books.google.ca/books?id=6lXTP0YU6_kC&printsec=frontcover&dq=Assembling+the+tree+of+life&hl=en&ei=LPuxTqDnA8bSiALLs7XpDw&sa=X&oi=book_result&ct=result&resnum=1&ved=0CDIQ6AEwAA#v=onepage&q&f=false. 
  3. ^ Lewontin, R. C. (1970). "The units of selection". Annual Review of Ecology and Systematics 1: 1–18. http://www.jstor.org/stable/2096764. 
  4. ^ Darwin, Charles (1859). "XIV". On The Origin of Species. p. 503. ISBN 0801413192. http://en.wikisource.org/wiki/On_the_Origin_of_Species_(1859)/Chapter_XIV. 
  5. ^ a b Kimura M (1991). "The neutral theory of molecular evolution: a review of recent evidence". Jpn. J. Genet. 66 (4): 367–86. doi:10.1266/jjg.66.367. PMID 1954033. http://www.jstage.jst.go.jp/article/jjg/66/4/66_367/_article. 
  6. ^ Provine, W. B. (1988). "Progress in evolution and meaning in life". Evolutionary progress. University of Chicago Press. pp. 49–79. 
  7. ^ National Academy of Science Institute of Medicine (2008). Science, Evolution, and Creationism. National Academy Press. ISBN 0309105862. http://www.nap.edu/catalog.php?record_id=11876. 
  8. ^ Moore, R.; Decker, M.; Cotner (2009). Chronology of the Evolution-Creationism Controversy. Greenwood. pp. 454. ISBN 0313362874. http://books.google.ca/books?id=4KwJRNgscdEC&printsec=frontcover&dq=Chronology+of+the+Evolution-Creationism+Controversy&hl=en&ei=6vuxTqD8F-afiAKAmuXwDw&sa=X&oi=book_result&ct=result&resnum=1&ved=0CC0Q6AEwAA#v=onepage&q&f=false. 
  9. ^ Futuyma, Douglas J., ed. (1999), Evolution, Science, and Society: Evolutionary Biology and the National Research Agenda, Office of University Publications, Rutgers, The State University of New Jersey, http://www.rci.rutgers.edu/~ecolevol/fulldoc.pdf 
  10. ^ a b Margulis, R.; Fester (1991). Symbiosis as a source of evolutionary innovation: Speciation and morphogenesis. The MIT Press. p. 470. ISBN 0262132699. http://books.google.ca/books?id=3sKzeiHUIUQC&pg=PA162&dq=inauthor:%22Lynn+Margulis%22+lamarck#v=onepage&q=inauthor%3A%22Lynn%20Margulis%22%20lamarck&f=false. 
  11. ^ a b c Gould, S.J. (2002). The Structure of Evolutionary Theory. Cambridge: Belknap Press (Harvard University Press). ISBN 0-674-00613-5. 
  12. ^ Ghiselin, Michael T. (September/October 1994). "Nonsense in schoolbooks: 'The Imaginary Lamarck'". The Textbook Letter. The Textbook League. http://www.textbookleague.org/54marck.htm. Retrieved 2008-01-23. 
  13. ^ Magner, Lois N. (2002). A History of the Life Sciences (Third ed.). Marcel Dekker, CRC Press. ISBN 978-0-203-91100-6. http://books.google.com/?id=YKJ6gVYbrGwC&printsec=frontcover#v=onepage&q. 
  14. ^ Jablonka, E.; Lamb, M. J. (2007). "Précis of evolution in four dimensions". Behavioural and Brain Sciences 30: 353–392. doi:10.1017/S0140525X07002221. http://journals.cambridge.org/download.php?file=%2FBBS%2FBBS30_04%2FS0140525X07002361a.pdf&code=eb63ecba4b606e8e388169c5ae3c5095. 
  15. ^ Burkhardt, F.; Smith, S., eds (1991). The correspondence of Charles Darwin. 7. Cambridge: Cambridge University Press. pp. 1858–1859. 
  16. ^ Sulloway, F. J. (2009). "Why Darwin rejected intelligent design". Journal of Biosciences 34 (2): 173–183. doi:10.1007/s12038-009-0020-8. 
  17. ^ Dawkins, R. (1990). Blind Watchmaker. Penguin Books. p. 368. ISBN 0140144811. 
  18. ^ Darwin, F. (1909). Cambridge University Press. p. 53. http://darwin-online.org.uk/pdf/1909_Foundations_F1555.pdf. 
  19. ^ Sober, E. (2009). "Did Darwin write the origin backwards?". Proceedings of the National Academy of Sciences 106 (S1): 10048–10055. Bibcode 2009PNAS..10610048S. doi:10.1073/pnas.0901109106. http://www.pnas.org/content/106/suppl.1/10048.full.pdf+html. 
  20. ^ Mayr, Ernst (2001) What evolution is. Weidenfeld & Nicolson, London. p165
  21. ^ Bowler, Peter J. (2003). Evolution: the history of an idea. Berkeley: University of California Press. pp. 145–146. ISBN 0-520-23693-9.  page 147"
  22. ^ Sokal RR, Crovello TJ (1970). "The biological species concept: A critical evaluation" (PDF). The American Naturalist 104 (936): 127–153. doi:10.1086/282646. JSTOR 2459191. http://hymenoptera.tamu.edu/courses/ento601/pdf/Sokal_Crovello_1970.pdf. 
  23. ^ Wallace, A (1858). "On the Tendency of Species to form Varieties and on the Perpetuation of Varieties and Species by Natural Means of Selection". Journal of the Proceedings of the Linnean Society of London. Zoology 3 (2): 53–62. doi:10.1098/rsnr.2006.0171. http://darwin-online.org.uk/content/frameset?itemID=F350&viewtype=text&pageseq=1. Retrieved 2007-05-13. 
  24. ^ Encyclopædia Britannica Online
  25. ^ Liu, Y. S.; Zhou, X. M.; Zhi, M. X.; Li, X. J.; Wan, Q. L. (2009). "Darwin's contributions to genetics". J Appl Genet 50 (3): 177–184. http://jay.up.poznan.pl/JAG/pdfy/2009_Volume_50/2009_Volume_50_3-177-184.pdf. 
  26. ^ Weiling F (1991). "Historical study: Johann Gregor Mendel 1822–1884". Am. J. Med. Genet. 40 (1): 1–25; discussion 26. doi:10.1002/ajmg.1320400103. PMID 1887835. 
  27. ^ Wright, S.. Evolution and the Genetics of Populations, Volume 1: Genetic and Biometric Foundations. University Of Chicago Press. p. 480. ISBN 0226910385. http://books.google.ca/books?id=4pTdTWi83ecC&printsec=frontcover&dq=sewall+wright+volume+1#v=onepage&q&f=false. 
  28. ^ Will Provine (1971). The Origins of Theoretical Population Genetics. University of Chicago Press. ISBN 0-226-68464-4. 
  29. ^ Stamhuis, Meijer and Zevenhuizen. Hugo de Vries on heredity, 1889–1903. Statistics, Mendelian laws, pangenes, mutations., Isis. 1999 Jun;90(2):238-67.
  30. ^ Quammen, D. (2006). The reluctant Mr. Darwin: An intimate portrait of Charles Darwin and the making of his theory of evolution. New York, NY: W.W. Norton & Company.
  31. ^ Bowler, Peter J. (1989). The Mendelian Revolution: The Emergence of Hereditarian Concepts in Modern Science and Society. Baltimore: Johns Hopkins University Press. ISBN 978-0-8018-3888-0. 
  32. ^ Watson, J. D.; Crick, F. H. C.. "Molecular structure of nucleic acids: A structure for deoxyribose nucleic acid". Nature 171 (4356): 737–738. Bibcode 1953Natur.171..737W. doi:10.1038/171737a0. PMID 13054692. http://profiles.nlm.nih.gov/SC/B/B/Y/W/_/scbbyw.pdf. 
  33. ^ Hennig, W.; Lieberman, B. S. (1999). Phylogenetic systematics (New edition (Mar 1 1999) ed.). University of Illinois Press. p. 280. ISBN 0252068149. http://books.google.ca/books?id=xsi6QcQPJGkC&printsec=frontcover&dq=phylogenetic+systematics#v=onepage&q&f=false. 
  34. ^ Phylogenetics: Theory and practice of phylogenetic systematics (2nd ed.). Wiley-Blackwell. 2011. p. 390. doi:10.1002/9781118017883.fmatter. 
  35. ^ Dobzhansky, T. (1973). "Nothing in biology makes sense except in the light of evolution". The American Biology Teacher 35 (3): 125–129. http://img.signaly.cz/upload/1/0/9a462eb6be1ed7828f57a184cde3c0/Dobzhansky.pdf. 
  36. ^ a b c d Kutschera U, Niklas K (2004). "The modern theory of biological evolution: an expanded synthesis". Naturwissenschaften 91 (6): 255–76. Bibcode 2004NW.....91..255K. doi:10.1007/s00114-004-0515-y. PMID 15241603. 
  37. ^ Cracraft, J.; Bybee, R. W., eds (2004). Evolutionary science and society: Educating a new generation. Revised Proceedings of the BSCS, AIBS Symposium. Chicago, IL. http://www.bscs.org/curriculumdevelopment/highschool/evolution/pdf.html. 
  38. ^ Avise, J. C.; Ayala, F. J. (2010). "In the Light of Evolution IV. The Human Condition (introduction).". Proceedings of the National Academy of Sciences USA 107 (S2): 8897–8901. doi:10.1073/pnas.100321410. http://faculty.sites.uci.edu/johncavise/files/2011/03/311-intro-to-ILE-IV.pdf. 
  39. ^ Sturm RA, Frudakis TN (2004). "Eye colour: portals into pigmentation genes and ancestry". Trends Genet. 20 (8): 327–32. doi:10.1016/j.tig.2004.06.010. PMID 15262401. 
  40. ^ a b Pearson H (2006). "Genetics: what is a gene?". Nature 441 (7092): 398–401. Bibcode 2006Natur.441..398P. doi:10.1038/441398a. PMID 16724031. 
  41. ^ Visscher PM, Hill WG, Wray NR (2008). "Heritability in the genomics era—concepts and misconceptions". Nat. Rev. Genet. 9 (4): 255–66. doi:10.1038/nrg2322. PMID 18319743. 
  42. ^ Oetting WS, Brilliant MH, King RA (1996). "The clinical spectrum of albinism in humans". Molecular medicine today 2 (8): 330–5. doi:10.1016/1357-4310(96)81798-9. PMID 8796918. 
  43. ^ a b Futuyma, Douglas J. (2005). Evolution. Sunderland, Massachusetts: Sinauer Associates, Inc. ISBN 0-87893-187-2. 
  44. ^ Phillips PC (2008). "Epistasis—the essential role of gene interactions in the structure and evolution of genetic systems". Nat. Rev. Genet. 9 (11): 855–67. doi:10.1038/nrg2452. PMC 2689140. PMID 18852697. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2689140. 
  45. ^ a b Wu R, Lin M (2006). "Functional mapping – how to map and study the genetic architecture of dynamic complex traits". Nat. Rev. Genet. 7 (3): 229–37. doi:10.1038/nrg1804. PMID 16485021. 
  46. ^ Jablonka, E.; Raz, G. (2009). "Transgenerational epigenetic inheritance: Prevalence, mechanisms and implications for the study of heredity and evolution.". The Quarterly Review of Biology 84 (2): 131–176. doi:10.1086/598822. PMID 19606595. http://compgen.unc.edu/wiki/images/d/df/JablonkaQtrRevBio2009.pdf. 
  47. ^ Bossdorf, O.; Arcuri, D.; Richards, C. L.; Pigliucci, M. (2010). "Experimental alteration of DNA methylation affects the phenotypic plasticity of ecologically relevant traits in Arabidopsis thaliana". Evolutionary Ecology 24 (3): 541–553. doi:10.1007/s10682-010-9372-7. http://www.springerlink.com/content/c847255ur67w2487/. 
  48. ^ Jablonka, E.; Lamb, M. (2005). Evolution in four dimensions: Genetic, epigenetic, behavioural and symbolic. MIT Press. ISBN 0-262-10107-6. http://books.google.ca/books?id=EaCiHFq3MWsC&printsec=frontcover. 
  49. ^ Jablonka, E.; Lamb, M. J. (2002). "The changing concept of epigenetics". Annals of the New York Academy of Sciences 981 (1): 82–96. Bibcode 2002NYASA.981...82J. doi:10.1111/j.1749-6632.2002.tb04913.x. http://a-c-elitzur.co.il/uploads/articlesdocs/Jablonka.pdf. 
  50. ^ Laland, K. N.; Sterelny, K. (2006). "Perspective: Seven reasons (not) to neglect niche construction". Evolution 60 (8): 1751–1762. doi:10.1111/j.0014-3820.2006.tb00520.x. http://lalandlab.st-andrews.ac.uk/pdf/laland_Evolution_2006.pdf. 
  51. ^ Chapman, M. J.; Margulis, L. (1998). "Morphogenesis by symbiogenesis". International Microbiology 1 (4): 319–326. PMID 10943381. http://www.im.microbios.org/04december98/14%20Chapman.pdf. 
  52. ^ Wilson, D. S.; Wilson, E. O. (2007). "Rethinking the theoretical foundation of sociobiology". The Quarterly Review of Biology 82 (4). http://evolution.binghamton.edu/dswilson/wp-content/uploads/2010/01/Rethinking-sociobiology.pdf. 
  53. ^ Harwood AJ; Harwood, J (1998). "Factors affecting levels of genetic diversity in natural populations". Philos. Trans. R. Soc. Lond., B, Biol. Sci. 353 (1366): 177–86. doi:10.1098/rstb.1998.0200. PMC 1692205. PMID 9533122. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1692205. 
  54. ^ a b Ewens W.J. (2004). Mathematical Population Genetics (2nd Edition). Springer-Verlag, New York. ISBN 0-387-20191-2. 
  55. ^ Butlin RK, Tregenza T (1998). "Levels of genetic polymorphism: marker loci versus quantitative traits". Philos. Trans. R. Soc. Lond., B, Biol. Sci. 353 (1366): 187–98. doi:10.1098/rstb.1998.0201. PMC 1692210. PMID 9533123. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1692210. 
  56. ^ Wetterbom A, Sevov M, Cavelier L, Bergström TF (2006). "Comparative genomic analysis of human and chimpanzee indicates a key role for indels in primate evolution". J. Mol. Evol. 63 (5): 682–90. doi:10.1007/s00239-006-0045-7. PMID 17075697. 
  57. ^ Sawyer SA, Parsch J, Zhang Z, Hartl DL (2007). "Prevalence of positive selection among nearly neutral amino acid replacements in Drosophila". Proc. Natl. Acad. Sci. U.S.A. 104 (16): 6504–10. Bibcode 2007PNAS..104.6504S. doi:10.1073/pnas.0701572104. PMC 1871816. PMID 17409186. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1871816. 
  58. ^ Hastings, P J; Lupski, JR; Rosenberg, SM; Ira, G (2009). "Mechanisms of change in gene copy number". Nature Reviews. Genetics 10 (8): 551–564. doi:10.1038/nrg2593. PMC 2864001. PMID 19597530. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2864001. 
  59. ^ Carroll SB, Grenier J, Weatherbee SD (2005). From DNA to Diversity: Molecular Genetics and the Evolution of Animal Design. Second Edition. Oxford: Blackwell Publishing. ISBN 1-4051-1950-0. 
  60. ^ Harrison P, Gerstein M (2002). "Studying genomes through the aeons: protein families, pseudogenes and proteome evolution". J Mol Biol 318 (5): 1155–74. doi:10.1016/S0022-2836(02)00109-2. PMID 12083509. 
  61. ^ Bowmaker JK (1998). "Evolution of colour vision in vertebrates". Eye (London, England) 12 (Pt 3b): 541–7. PMID 9775215. 
  62. ^ Gregory TR, Hebert PD (1999). "The modulation of DNA content: proximate causes and ultimate consequences". Genome Res. 9 (4): 317–24. doi:10.1101/gr.9.4.317. PMID 10207154. http://genome.cshlp.org/content/9/4/317.full. 
  63. ^ Hurles M (2004). "Gene duplication: the genomic trade in spare parts". PLoS Biol. 2 (7): E206. doi:10.1371/journal.pbio.0020206. PMC 449868. PMID 15252449. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=449868. 
  64. ^ Liu N, Okamura K, Tyler DM (2008). "The evolution and functional diversification of animal microRNA genes". Cell Res. 18 (10): 985–96. doi:10.1038/cr.2008.278. PMC 2712117. PMID 18711447. http://www.nature.com/cr/journal/v18/n10/full/cr2008278a.html. 
  65. ^ Siepel A (2009). "Darwinian alchemy: Human genes from noncoding DNA". Genome Res. 19 (10): 1693–5. doi:10.1101/gr.098376.109. PMC 2765273. PMID 19797681. http://genome.cshlp.org/content/19/10/1693.full. 
  66. ^ Orengo CA, Thornton JM (2005). "Protein families and their evolution-a structural perspective". Annu. Rev. Biochem. 74 (1): 867–900. doi:10.1146/annurev.biochem.74.082803.133029. PMID 15954844. 
  67. ^ Long M, Betrán E, Thornton K, Wang W (2003). "The origin of new genes: glimpses from the young and old". Nat. Rev. Genet. 4 (11): 865–75. doi:10.1038/nrg1204. PMID 14634634. 
  68. ^ Wang M, Caetano-Anollés G (2009). "The evolutionary mechanics of domain organization in proteomes and the rise of modularity in the protein world". Structure 17 (1): 66–78. doi:10.1016/j.str.2008.11.008. PMID 19141283. 
  69. ^ Weissman KJ, Müller R (2008). "Protein-protein interactions in multienzyme megasynthetases". Chembiochem 9 (6): 826–48. doi:10.1002/cbic.200700751. PMID 18357594. 
  70. ^ Radding C (1982). "Homologous pairing and strand exchange in genetic recombination". Annu. Rev. Genet. 16 (1): 405–37. doi:10.1146/annurev.ge.16.120182.002201. PMID 6297377. 
  71. ^ Agrawal AF (2006). "Evolution of sex: why do organisms shuffle their genotypes?". Curr. Biol. 16 (17): R696. doi:10.1016/j.cub.2006.07.063. PMID 16950096. 
  72. ^ Peters AD, Otto SP (2003). "Liberating genetic variance through sex". Bioessays 25 (6): 533–7. doi:10.1002/bies.10291. PMID 12766942. 
  73. ^ Goddard MR, Godfray HC, Burt A (2005). "Sex increases the efficacy of natural selection in experimental yeast populations". Nature 434 (7033): 636–40. Bibcode 2005Natur.434..636G. doi:10.1038/nature03405. PMID 15800622. 
  74. ^ a b Morjan C, Rieseberg L (2004). "How species evolve collectively: implications of gene flow and selection for the spread of advantageous alleles". Mol. Ecol. 13 (6): 1341–56. doi:10.1111/j.1365-294X.2004.02164.x. PMC 2600545. PMID 15140081. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2600545. 
  75. ^ Boucher Y, Douady CJ, Papke RT, Walsh DA, Boudreau ME, Nesbo CL, Case RJ, Doolittle WF (2003). "Lateral gene transfer and the origins of prokaryotic groups". Annu Rev Genet 37 (1): 283–328. doi:10.1146/annurev.genet.37.050503.084247. PMID 14616063. 
  76. ^ Walsh T (2006). "Combinatorial genetic evolution of multiresistance". Curr. Opin. Microbiol. 9 (5): 476–82. doi:10.1016/j.mib.2006.08.009. PMID 16942901. 
  77. ^ Kondo N, Nikoh N, Ijichi N, Shimada M, Fukatsu T (2002). "Genome fragment of Wolbachia endosymbiont transferred to X chromosome of host insect". Proc. Natl. Acad. Sci. U.S.A. 99 (22): 14280–5. Bibcode 2002PNAS...9914280K. doi:10.1073/pnas.222228199. PMC 137875. PMID 12386340. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=137875. 
  78. ^ Sprague G (1991). "Genetic exchange between kingdoms". Curr. Opin. Genet. Dev. 1 (4): 530–3. doi:10.1016/S0959-437X(05)80203-5. PMID 1822285. 
  79. ^ Gladyshev EA, Meselson M, Arkhipova IR (2008). "Massive horizontal gene transfer in bdelloid rotifers". Science 320 (5880): 1210–3. Bibcode 2008Sci...320.1210G. doi:10.1126/science.1156407. PMID 18511688. 
  80. ^ Baldo A, McClure M (1 September 1999). "Evolution and horizontal transfer of dUTPase-encoding genes in viruses and their hosts". J. Virol. 73 (9): 7710–21. PMC 104298. PMID 10438861. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=104298. 
  81. ^ River, M. C. and Lake, J. A. (2004). "The ring of life provides evidence for a genome fusion origin of eukaryotes". Nature 431 (9): 152–5. Bibcode 2004Natur.431..152R. doi:10.1038/nature02848. PMID 15356622. 
  82. ^ a b c Hurst LD (2009). "Fundamental concepts in genetics: genetics and the understanding of selection". Nat. Rev. Genet. 10 (2): 83–93. doi:10.1038/nrg2506. PMID 19119264. 
  83. ^ a b c Orr HA (2009). "Fitness and its role in evolutionary genetics". Nat. Rev. Genet. 10 (8): 531–9. doi:10.1038/nrg2603. PMC 2753274. PMID 19546856. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2753274. 
  84. ^ Haldane J (1959). "The theory of natural selection today". Nature 183 (4663): 710–3. Bibcode 1959Natur.183..710H. doi:10.1038/183710a0. PMID 13644170. 
  85. ^ Lande R, Arnold SJ (1983). "The measurement of selection on correlated characters". Evolution 37 (6): 1210–26. doi:10.2307/2408842. JSTOR 2408842. 
  86. ^ Goldberg, Emma E; Igić, B (2008). "On phylogenetic tests of irreversible evolution". Evolution 62 (11): 2727–2741. doi:10.1111/j.1558-5646.2008.00505.x. PMID 18764918. 
  87. ^ Collin, Rachel; Miglietta, MP (2008). "Reversing opinions on Dollo's Law". Trends in Ecology & Evolution 23 (11): 602–609. doi:10.1016/j.tree.2008.06.013. PMID 18814933. 
  88. ^ Hoekstra H, Hoekstra J, Berrigan D, Vignieri S, Hoang A, Hill C, Beerli P, Kingsolver J (2001). "Strength and tempo of directional selection in the wild". Proc. Natl. Acad. Sci. U.S.A. 98 (16): 9157–60. Bibcode 2001PNAS...98.9157H. doi:10.1073/pnas.161281098. PMC 55389. PMID 11470913. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=55389. 
  89. ^ Felsenstein (1 November 1979). "Excursions along the Interface between Disruptive and Stabilizing Selection". Genetics 93 (3): 773–95. PMC 1214112. PMID 17248980. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1214112. 
  90. ^ Andersson M, Simmons L (2006). "Sexual selection and mate choice". Trends Ecol. Evol. (Amst.) 21 (6): 296–302. doi:10.1016/j.tree.2006.03.015. PMID 16769428. 
  91. ^ Kokko H, Brooks R, McNamara J, Houston A (2002). "The sexual selection continuum". Proc. Biol. Sci. 269 (1498): 1331–40. doi:10.1098/rspb.2002.2020. PMC 1691039. PMID 12079655. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1691039. 
  92. ^ Hunt J, Brooks R, Jennions M, Smith M, Bentsen C, Bussière L (2004). "High-quality male field crickets invest heavily in sexual display but die young". Nature 432 (7020): 1024–7. Bibcode 2004Natur.432.1024H. doi:10.1038/nature03084. PMID 15616562. 
  93. ^ Odum, EP (1971) Fundamentals of ecology, third edition, Saunders New York
  94. ^ Okasha, S. (2007). Evolution and the Levels of Selection. Oxford University Press. ISBN 0-19-926797-9. 
  95. ^ a b Gould SJ (1998). "Gulliver's further travels: the necessity and difficulty of a hierarchical theory of selection". Philos. Trans. R. Soc. Lond., B, Biol. Sci. 353 (1366): 307–14. doi:10.1098/rstb.1998.0211. PMC 1692213. PMID 9533127. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1692213. 
  96. ^ Mayr E (1997). "The objects of selection". Proc. Natl. Acad. Sci. U.S.A. 94 (6): 2091–4. Bibcode 1997PNAS...94.2091M. doi:10.1073/pnas.94.6.2091. PMC 33654. PMID 9122151. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=33654. 
  97. ^ Maynard Smith J (1998). "The units of selection". Novartis Found. Symp. 213: 203–11; discussion 211–7. PMID 9653725. 
  98. ^ Hickey DA (1992). "Evolutionary dynamics of transposable elements in prokaryotes and eukaryotes". Genetica 86 (1–3): 269–74. doi:10.1007/BF00133725. PMID 1334911. 
  99. ^ Gould SJ, Lloyd EA (1999). "Individuality and adaptation across levels of selection: how shall we name and generalise the unit of Darwinism?". Proc. Natl. Acad. Sci. U.S.A. 96 (21): 11904–9. Bibcode 1999PNAS...9611904G. doi:10.1073/pnas.96.21.11904. PMC 18385. PMID 10518549. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=18385. 
  100. ^ Lynch, M. (2007). "The frailty of adaptive hypotheses for the origins of organismal complexity". PNAS 104: 8597–8604. Bibcode 2007PNAS..104.8597L. doi:10.1073/pnas.0702207104. 
  101. ^ Smith N.G.C., Webster M.T., Ellegren, H. (2002). "Deterministic Mutation Rate Variation in the Human Genome". Genome Research 12 (9): 1350–1356. doi:10.1101/gr.220502. http://genome.cshlp.org/content/12/9/1350.abstract. 
  102. ^ Petrov DA, Sangster TA, Johnston JS, Hartl DL, Shaw KL (2000). "Evidence for DNA loss as a determinant of genome size". Science 287 (5455): 1060–1062. Bibcode 2000Sci...287.1060P. doi:10.1126/science.287.5455.1060. 
  103. ^ Petrov DA (2002). "DNA loss and evolution of genome size in Drosophila". Genetica 115 (1): 81–91. doi:10.1023/A:1016076215168. 
  104. ^ Kiontke K, Barriere A , Kolotuev I, Podbilewicz B , Sommer R, Fitch DHA , Felix MA (2007). "Trends, stasis, and drift in the evolution of nematode vulva development". Current Biology 17 (22): 1925–1937. doi:10.1016/j.cub.2007.10.061. PMID 18024125. 
  105. ^ Braendle C, Baer CF, Felix MA (2010). "Bias and Evolution of the Mutationally Accessible Phenotypic Space in a Developmental System". PLoS Genetics 6 (3). doi:10.1371/journal.pgen.1000877. 
  106. ^ Palmer, RA (2004). "Symmetry breaking and the evolution of development". Science 306 (5697): 828–833. Bibcode 2004Sci...306..828P. doi:10.1126/science.1103707. PMID 15514148. 
  107. ^ West-Eberhard, M-J. (2003). Developmental plasticity and evolution. New York: Oxford University Press. ISBN 978-0-19-512235-0. 
  108. ^ Stoltzfus, A and Yampolsky, L.Y. (2009). "Climbing Mount Probable: Mutation as a Cause of Nonrandomness in Evolution". J Hered 100 (5): 637–647. doi:10.1093/jhered/esp048. PMID 19625453. 
  109. ^ Yampolsky, L.Y. and Stoltzfus, A (2001). "Bias in the introduction of variation as an orienting factor in evolution". Evol Dev 3 (2): 73–83. doi:10.1046/j.1525-142x.2001.003002073.x. PMID 11341676. 
  110. ^ Haldane, JBS (1933). "The Part Played by Recurrent Mutation in Evolution". American Naturalist 67: 5–19. http://www.jstor.org/stable/2457127. 
  111. ^ Protas, Meredith; Conrad, M; Gross, JB; Tabin, C; Borowsky, R (2007). "Regressive evolution in the Mexican cave tetra, Astyanax mexicanus". Current Biology 17 (5): 452–454. doi:10.1016/j.cub.2007.01.051. PMC 2570642. PMID 17306543. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2570642. 
  112. ^ Maughan H, Masel J, Birky WC, Nicholson WL (2007). "The roles of mutation accumulation and selection in loss of sporulation in experimental populations of Bacillus subtilis". Genetics 177: 937–948. doi:10.1534/genetics.107.075663. 
  113. ^ Masel J, King OD, Maughan H (2007). "The loss of adaptive plasticity during long periods of environmental stasis". American Naturalist 169 (1): 38–46. doi:10.1086/510212. 
  114. ^ a b Masel J (2011). "Genetic drift". Current Biology 21 (20): R837-R838. doi:10.1016/j.cub.2011.08.007. http://www.sciencedirect.com/science/article/pii/S0960982211008827. 
  115. ^ Lande R (1989). "Fisherian and Wrightian theories of speciation". Genome 31 (1): 221–7. PMID 2687093. 
  116. ^ Mitchell-Olds, Thomas; Willis, JH; Goldstein, DB (2007). "Which evolutionary processes influence natural genetic variation for phenotypic traits?". Nature Reviews Genetics 8 (11): 845–856. doi:10.1038/nrg2207. PMID 17943192. 
  117. ^ Nei M (2005). "Selectionism and neutralism in molecular evolution". Mol. Biol. Evol. 22 (12): 2318–42. doi:10.1093/molbev/msi242. PMC 1513187. PMID 16120807. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1513187. 
  118. ^ Kimura M (1989). "The neutral theory of molecular evolution and the world view of the neutralists". Genome 31 (1): 24–31. PMID 2687096. 
  119. ^ Kreitman M (1996). "The neutral theory is dead. Long live the neutral theory". Bioessays 18 (8): 678–83; discussion 683. doi:10.1002/bies.950180812. PMID 8760341. 
  120. ^ Leigh E.G. (Jr) (2007). "Neutral theory: a historical perspective.". Journal of Evolutionary Biology 20 (6): 2075–91. doi:10.1111/j.1420-9101.2007.01410.x. PMID 17956380. 
  121. ^ a b Gillespie, John H. (2001). "Is the population size of a species relevant to its evolution?". Evolution 55 (11): 2161–2169. PMID 11794777. 
  122. ^ R.A. Neher and B.I. Shraiman (2011). "Genetic Draft and Quasi-Neutrality in Large Facultatively Sexual Populations". Genetics 188: 975–996. doi:10.1534/genetics.111.128876. 
  123. ^ Otto S, Whitlock M (1 June 1997). "The probability of fixation in populations of changing size". Genetics 146 (2): 723–33. PMC 1208011. PMID 9178020. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1208011. 
  124. ^ a b Charlesworth B (2009). "Fundamental concepts in genetics: Effective population size and patterns of molecular evolution and variation". Nat. Rev. Genet. 10 (3): 195–205. doi:10.1038/nrg2526. PMID 19204717. 
  125. ^ Asher D. Cutter and Jae Young Choi (2010). "Natural selection shapes nucleotide polymorphism across the genome of the nematode Caenorhabditis briggsae". Genome Research 20: 1103–1111. 
  126. ^ Lien S, Szyda J, Schechinger B, Rappold G, Arnheim N (2000). "Evidence for heterogeneity in recombination in the human pseudoautosomal region: high resolution analysis by sperm typing and radiation-hybrid mapping". Am. J. Hum. Genet. 66 (2): 557–66. doi:10.1086/302754. PMC 1288109. PMID 10677316. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1288109. 
  127. ^ Barton, N H (2000). "Genetic hitchhiking". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 355 (1403): 1553–1562. doi:10.1098/rstb.2000.0716. PMC 1692896. PMID 11127900. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1692896. 
  128. ^ Wright, Sewall (1932). "The roles of mutation, inbreeding, crossbreeding and selection in evolution". Proc. 6th Int. Cong. Genet 1: 356–366. http://www.blackwellpublishing.com/ridley/classictexts/wright.asp. 
  129. ^ Coyne; Barton, Turelli (1997). "Perspective: A Critique of Sewall Wright's Shifting Balance Theory of Evolution". Evolution. 3 51: 643–671. 
  130. ^ a b c Scott EC, Matzke NJ (2007). "Biological design in science classrooms". Proc. Natl. Acad. Sci. U.S.A.. 104 1 (suppl_1): 8669–76. Bibcode 2007PNAS..104.8669S. doi:10.1073/pnas.0701505104. PMC 1876445. PMID 17494747. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1876445. 
  131. ^ Hendry AP, Kinnison MT (2001). "An introduction to microevolution: rate, pattern, process". Genetica 112–113: 1–8. doi:10.1023/A:1013368628607. PMID 11838760. 
  132. ^ Leroi AM (2000). "The scale independence of evolution". Evol. Dev. 2 (2): 67–77. doi:10.1046/j.1525-142x.2000.00044.x. PMID 11258392. 
  133. ^ Gould 2002, pp. 657–8
  134. ^ Gould SJ (1994). "Tempo and mode in the macroevolutionary reconstruction of Darwinism". Proc. Natl. Acad. Sci. U.S.A. 91 (15): 6764–71. Bibcode 1994PNAS...91.6764G. doi:10.1073/pnas.91.15.6764. PMC 44281. PMID 8041695. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=44281. 
  135. ^ Jablonski, D. (2000). "Micro- and macroevolution: scale and hierarchy in evolutionary biology and paleobiology". Paleobiology 26 (sp4): 15–52. doi:10.1666/0094-8373(2000)26[15:MAMSAH]2.0.CO;2. 
  136. ^ Michael J. Dougherty. Is the human race evolving or devolving? Scientific American July 20, 1998.
  137. ^ TalkOrigins Archive response to Creationist claims – Claim CB932: Evolution of degenerate forms
  138. ^ Carroll SB (2001). "Chance and necessity: the evolution of morphological complexity and diversity". Nature 409 (6823): 1102–9. doi:10.1038/35059227. PMID 11234024. 
  139. ^ Whitman W, Coleman D, Wiebe W (1998). "Prokaryotes: the unseen majority". Proc Natl Acad Sci U S A 95 (12): 6578–83. Bibcode 1998PNAS...95.6578W. doi:10.1073/pnas.95.12.6578. PMC 33863. PMID 9618454. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=33863. 
  140. ^ a b Schloss P, Handelsman J (2004). "Status of the microbial census". Microbiol Mol Biol Rev 68 (4): 686–91. doi:10.1128/MMBR.68.4.686-691.2004. PMC 539005. PMID 15590780. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=539005. 
  141. ^ Nealson K (1999). "Post-Viking microbiology: new approaches, new data, new insights". Orig Life Evol Biosph 29 (1): 73–93. doi:10.1023/A:1006515817767. PMID 11536899. 
  142. ^ Buckling A, Craig Maclean R, Brockhurst MA, Colegrave N (2009). "The Beagle in a bottle". Nature 457 (7231): 824–9. Bibcode 2009Natur.457..824B. doi:10.1038/nature07892. PMID 19212400. 
  143. ^ Elena SF, Lenski RE (2003). "Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation". Nat. Rev. Genet. 4 (6): 457–69. doi:10.1038/nrg1088. PMID 12776215. 
  144. ^ Mayr, Ernst 1982. The growth of biological thought. Harvard. p483: "Adaptation... could no longer be considered a static condition, a product of a creative past and became instead a continuing dynamic process."
  145. ^ The Oxford Dictionary of Science defines adaptation as "Any change in the structure or functioning of an organism that makes it better suited to its environment".
  146. ^ Orr H (2005). "The genetic theory of adaptation: a brief history". Nat. Rev. Genet. 6 (2): 119–27. doi:10.1038/nrg1523. PMID 15716908. 
  147. ^ Dobzhansky, T.; Hecht, MK; Steere, WC (1968). "On some fundamental concepts of evolutionary biology". Evolutionary biology volume 2 (1st ed.). New York: Appleton-Century-Crofts. pp. 1–34. 
  148. ^ Dobzhansky, T. (1970). Genetics of the evolutionary process. N.Y.: Columbia. pp. 4–6, 79–82, 84–87. ISBN 0-231-02837-7. 
  149. ^ Dobzhansky, T. (1956). "Genetics of natural populations XXV. Genetic changes in populations of Drosophila pseudoobscura and Drosphila persimilis in some locations in California". Evolution 10 (1): 82–92. doi:10.2307/2406099. JSTOR 2406099. 
  150. ^ Nakajima A, Sugimoto Y, Yoneyama H, Nakae T (2002). "High-level fluoroquinolone resistance in Pseudomonas aeruginosa due to interplay of the MexAB-OprM efflux pump and the DNA gyrase mutation". Microbiol. Immunol. 46 (6): 391–5. PMID 12153116. 
  151. ^ Blount ZD, Borland CZ, Lenski RE (2008). "Inaugural Article: Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli". Proc. Natl. Acad. Sci. U.S.A. 105 (23): 7899–906. Bibcode 2008PNAS..105.7899B. doi:10.1073/pnas.0803151105. PMC 2430337. PMID 18524956. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2430337. 
  152. ^ Okada H, Negoro S, Kimura H, Nakamura S (1983). "Evolutionary adaptation of plasmid-encoded enzymes for degrading nylon oligomers". Nature 306 (5939): 203–6. Bibcode 1983Natur.306..203O. doi:10.1038/306203a0. PMID 6646204. 
  153. ^ Ohno S (1984). "Birth of a unique enzyme from an alternative reading frame of the preexisted, internally repetitious coding sequence". Proc. Natl. Acad. Sci. U.S.A. 81 (8): 2421–5. Bibcode 1984PNAS...81.2421O. doi:10.1073/pnas.81.8.2421. PMC 345072. PMID 6585807. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=345072. 
  154. ^ Copley SD (2000). "Evolution of a metabolic pathway for degradation of a toxic xenobiotic: the patchwork approach". Trends Biochem. Sci. 25 (6): 261–5. doi:10.1016/S0968-0004(00)01562-0. PMID 10838562. 
  155. ^ Crawford RL, Jung CM, Strap JL (2007). "The recent evolution of pentachlorophenol (PCP)-4-monooxygenase (PcpB) and associated pathways for bacterial degradation of PCP". Biodegradation 18 (5): 525–39. doi:10.1007/s10532-006-9090-6. PMID 17123025. 
  156. ^ Eshel I (1973). "Clone-selection and optimal rates of mutation". Journal of Applied Probability 10 (4): 728–738. doi:10.2307/3212376. JSTOR 3212376. 
  157. ^ Masel J, Bergman A, (2003). "The evolution of the evolvability properties of the yeast prion [PSI+]". Evolution 57 (7): 1498–1512. PMID 12940355. 
  158. ^ Lancaster AK, Bardill JP, True HL, Masel J (2010). "The Spontaneous Appearance Rate of the Yeast Prion [PSI+ and Its Implications for the Evolution of the Evolvability Properties of the [PSI+] System"]. Genetics 184 (2): 393–400. doi:10.1534/genetics.109.110213. PMC 2828720. PMID 19917766. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2828720. 
  159. ^ Draghi J, Wagner G (2008). "Evolution of evolvability in a developmental model". Theoretical Population Biology 62: 301–315. 
  160. ^ a b Bejder L, Hall BK (2002). "Limbs in whales and limblessness in other vertebrates: mechanisms of evolutionary and developmental transformation and loss". Evol. Dev. 4 (6): 445–58. doi:10.1046/j.1525-142X.2002.02033.x. PMID 12492145. 
  161. ^ Young, Nathan M.; Hallgrímsson, B (2005). "Serial homology and the evolution of mammalian limb covariation structure". Evolution 59 (12): 2691–704. doi:10.1554/05-233.1. PMID 16526515. http://www.bioone.org/doi/abs/10.1554/05-233.1. Retrieved 2009-09-24. 
  162. ^ a b Penny D, Poole A (1999). "The nature of the last universal common ancestor". Curr. Opin. Genet. Dev. 9 (6): 672–77. doi:10.1016/S0959-437X(99)00020-9. PMID 10607605. 
  163. ^ Hall, Brian K (2003). "Descent with modification: the unity underlying homology and homoplasy as seen through an analysis of development and evolution". Biological Reviews of the Cambridge Philosophical Society 78 (3): 409–433. doi:10.1017/S1464793102006097. PMID 14558591. 
  164. ^ Shubin, Neil; Tabin, C; Carroll, S (2009). "Deep homology and the origins of evolutionary novelty". Nature 457 (7231): 818–823. Bibcode 2009Natur.457..818S. doi:10.1038/nature07891. PMID 19212399. 
  165. ^ a b c Fong D, Kane T, Culver D (1995). "Vestigialization and Loss of Nonfunctional Characters". Ann. Rev. Ecol. Syst. 26 (4): 249–68. doi:10.1146/annurev.es.26.110195.001341. PMID 12733778. 
  166. ^ Zhang Z, Gerstein M (2004). "Large-scale analysis of pseudogenes in the human genome". Curr. Opin. Genet. Dev. 14 (4): 328–35. doi:10.1016/j.gde.2004.06.003. PMID 15261647. 
  167. ^ Jeffery WR (2005). "Adaptive evolution of eye degeneration in the Mexican blind cavefish". J. Hered. 96 (3): 185–96. doi:10.1093/jhered/esi028. PMID 15653557. 
  168. ^ Maxwell EE, Larsson HC (2007). "Osteology and myology of the wing of the Emu (Dromaius novaehollandiae) and its bearing on the evolution of vestigial structures". J. Morphol. 268 (5): 423–41. doi:10.1002/jmor.10527. PMID 17390336. 
  169. ^ Silvestri AR, Singh I (2003). "The unresolved problem of the third molar: would people be better off without it?". Journal of the American Dental Association (1939) 134 (4): 450–5. doi:10.1146/annurev.es.26.110195.001341. PMID 12733778. http://jada.ada.org/cgi/content/full/134/4/450. 
  170. ^ Coyne, Jerry A. (2009). Why Evolution is True. Penguin Group. p. 62. ISBN 9780670020539. 
  171. ^ Darwin, Charles. (1872) The Expression of the Emotions in Man and Animals John Murray, London.
  172. ^ Peter Gray (2007). Psychology (fifth ed.). Worth Publishers. p. 66. ISBN 0-7167-0617-2. 
  173. ^ Coyne, Jerry A. (2009). Why Evolution is True. Penguin Group. pp. 85–86. ISBN 978-0-670-02053. 
  174. ^ Anthony Stevens (1982). Archetype: A Natural History of the Self. Routledge & Kegan Paul. p. 87. ISBN 0-7100-0980-1. 
  175. ^ a b Gould 2002, pp. 1235–6
  176. ^ Pallen, Mark J.; Matzke, NJ (2006-10). "From The Origin of Species to the origin of bacterial flagella". Nat Rev Micro 4 (10): 784–790. doi:10.1038/nrmicro1493. PMID 16953248. http://home.planet.nl/~gkorthof/pdf/Pallen_Matzke.pdf. Retrieved 2009-09-18. 
  177. ^ Clements, Abigail; Bursac, D; Gatsos, X; Perry, AJ; Civciristov, S; Celik, N; Likic, VA; Poggio, S et al. (2009). "The reducible complexity of a mitochondrial molecular machine". Proceedings of the National Academy of Sciences 106 (37): 15791–15795. Bibcode 2009PNAS..10615791C. doi:10.1073/pnas.106.37.15791. PMC 2747197. PMID 19717453. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2747197. 
  178. ^ Piatigorsky J, Kantorow M, Gopal-Srivastava R, Tomarev SI (1994). "Recruitment of enzymes and stress proteins as lens crystallins". EXS 71: 241–50. PMID 8032155. 
  179. ^ Wistow G (1993). "Lens crystallins: gene recruitment and evolutionary dynamism". Trends Biochem. Sci. 18 (8): 301–6. doi:10.1016/0968-0004(93)90041-K. PMID 8236445. 
  180. ^ Hardin G (1960). "The competitive exclusion principle". Science 131 (3409): 1292–7. Bibcode 1960Sci...131.1292H. doi:10.1126/science.131.3409.1292. PMID 14399717. 
  181. ^ Kocher TD (2004). "Adaptive evolution and explosive speciation: the cichlid fish model". Nat. Rev. Genet. 5 (4): 288–98. doi:10.1038/nrg1316. PMID 15131652. http://hcgs.unh.edu/staff/kocher/pdfs/Kocher2004.pdf. 
  182. ^ Johnson NA, Porter AH (2001). "Toward a new synthesis: population genetics and evolutionary developmental biology". Genetica 112–113: 45–58. doi:10.1023/A:1013371201773. PMID 11838782. 
  183. ^ Baguñà J, Garcia-Fernàndez J (2003). "Evo-Devo: the long and winding road". Int. J. Dev. Biol. 47 (7–8): 705–13. PMID 14756346. http://www.ijdb.ehu.es/web/paper.php?doi=14756346. 
    *Love AC. (2003). "Evolutionary Morphology, Innovation and the Synthesis of Evolutionary and Developmental Biology". Biology and Philosophy 18 (2): 309–345. doi:10.1023/A:1023940220348. http://www.springerlink.com/content/k7745m8871l3m360/. 
  184. ^ Allin EF (1975). "Evolution of the mammalian middle ear". J. Morphol. 147 (4): 403–37. doi:10.1002/jmor.1051470404. PMID 1202224. 
  185. ^ Harris MP, Hasso SM, Ferguson MW, Fallon JF (2006). "The development of archosaurian first-generation teeth in a chicken mutant". Curr. Biol. 16 (4): 371–7. doi:10.1016/j.cub.2005.12.047. PMID 16488870. 
  186. ^ Carroll SB (2008). "Evo-devo and an expanding evolutionary synthesis: a genetic theory of morphological evolution". Cell 134 (1): 25–36. doi:10.1016/j.cell.2008.06.030. PMID 18614008. 
  187. ^ Wade MJ (2007). "The co-evolutionary genetics of ecological communities". Nat. Rev. Genet. 8 (3): 185–95. doi:10.1038/nrg2031. PMID 17279094. 
  188. ^ Geffeney S, Brodie ED, Ruben PC, Brodie ED (2002). "Mechanisms of adaptation in a predator-prey arms race: TTX-resistant sodium channels". Science 297 (5585): 1336–9. Bibcode 2002Sci...297.1336G. doi:10.1126/science.1074310. PMID 12193784. 
    *Brodie ED, Ridenhour BJ, Brodie ED (2002). "The evolutionary response of predators to dangerous prey: hotspots and coldspots in the geographic mosaic of coevolution between garter snakes and newts". Evolution 56 (10): 2067–82. PMID 12449493. 
    *Sean B. Carroll (December 21, 2009). "Remarkable Creatures – Clues to Toxins in Deadly Delicacies of the Animal Kingdom". New York Times. http://www.nytimes.com/2009/12/22/science/22creature.html?hpw. 
  189. ^ Sachs J (2006). "Cooperation within and among species". J. Evol. Biol. 19 (5): 1415–8; discussion 1426–36. doi:10.1111/j.1420-9101.2006.01152.x. PMID 16910971. 
    *Nowak M (2006). "Five rules for the evolution of cooperation". Science 314 (5805): 1560–3. Bibcode 2006Sci...314.1560N. doi:10.1126/science.1133755. PMID 17158317. 
  190. ^ Paszkowski U (2006). "Mutualism and parasitism: the yin and yang of plant symbioses". Curr. Opin. Plant Biol. 9 (4): 364–70. doi:10.1016/j.pbi.2006.05.008. PMID 16713732. 
  191. ^ Hause B, Fester T (2005). "Molecular and cell biology of arbuscular mycorrhizal symbiosis". Planta 221 (2): 184–96. doi:10.1007/s00425-004-1436-x. PMID 15871030. 
  192. ^ Bertram J (2000). "The molecular biology of cancer". Mol. Aspects Med. 21 (6): 167–223. doi:10.1016/S0098-2997(00)00007-8. PMID 11173079. 
  193. ^ Reeve HK, Hölldobler B (2007). "The emergence of a superorganism through intergroup competition". Proc Natl Acad Sci U S A. 104 (23): 9736–40. Bibcode 2007PNAS..104.9736R. doi:10.1073/pnas.0703466104. PMC 1887545. PMID 17517608. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1887545. 
  194. ^ Axelrod R, Hamilton W (2005). "The evolution of cooperation". Science 211 (4489): 1390–6. Bibcode 1981Sci...211.1390A. doi:10.1126/science.7466396. PMID 7466396. 
  195. ^ Wilson EO, Hölldobler B (2005). "Eusociality: origin and consequences". Proc. Natl. Acad. Sci. U.S.A. 102 (38): 13367–71. Bibcode 2005PNAS..10213367W. doi:10.1073/pnas.0505858102. PMC 1224642. PMID 16157878. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1224642. 
  196. ^ a b Gavrilets S (2003). "Perspective: models of speciation: what have we learned in 40 years?". Evolution 57 (10): 2197–215. doi:10.1554/02-727. PMID 14628909. 
  197. ^ a b c de Queiroz K (2005). "Ernst Mayr and the modern concept of species". Proc. Natl. Acad. Sci. U.S.A. 102 (Suppl 1): 6600–7. Bibcode 2005PNAS..102.6600D. doi:10.1073/pnas.0502030102. PMC 1131873. PMID 15851674. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1131873. 
  198. ^ a b Ereshefsky, M. (1992). "Eliminative pluralism.". Philosophy of Science 59 (4): 671–690. doi:10.1086/289701. JSTOR 188136. 
  199. ^ Mayr, E. (1942). Systematics and the Origin of Species. New York: Columbia Univ. Press. ISBN 0231054491. 
  200. ^ Fraser C, Alm EJ, Polz MF, Spratt BG, Hanage WP (2009). "The bacterial species challenge: making sense of genetic and ecological diversity". Science 323 (5915): 741–6. Bibcode 2009Sci...323..741F. doi:10.1126/science.1159388. PMID 19197054. 
  201. ^ Short RV (1975). "The contribution of the mule to scientific thought". J. Reprod. Fertil. Suppl. (23): 359–64. PMID 1107543. 
  202. ^ Gross B, Rieseberg L (2005). "The ecological genetics of homoploid hybrid speciation". J. Hered. 96 (3): 241–52. doi:10.1093/jhered/esi026. PMC 2517139. PMID 15618301. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2517139. 
  203. ^ Burke JM, Arnold ML (2001). "Genetics and the fitness of hybrids". Annu. Rev. Genet. 35 (1): 31–52. doi:10.1146/annurev.genet.35.102401.085719. PMID 11700276. 
  204. ^ Vrijenhoek RC (2006). "Polyploid hybrids: multiple origins of a treefrog species". Curr. Biol. 16 (7): R245. doi:10.1016/j.cub.2006.03.005. PMID 16581499. 
  205. ^ Rice, W.R.; Hostert (1993). "Laboratory experiments on speciation: what have we learned in 40 years". Evolution 47 (6): 1637–1653. doi:10.2307/2410209. 
    *Jiggins CD, Bridle JR (2004). "Speciation in the apple maggot fly: a blend of vintages?". Trends Ecol. Evol. (Amst.) 19 (3): 111–4. doi:10.1016/j.tree.2003.12.008. PMID 16701238. 
    *Boxhorn, J (1995). "Observed Instances of Speciation". TalkOrigins Archive. http://www.talkorigins.org/faqs/faq-speciation.html. Retrieved 2008-12-26. 
    *Weinberg JR, Starczak VR, Jorg, D (1992). "Evidence for Rapid Speciation Following a Founder Event in the Laboratory". Evolution 46 (4): 1214–20. doi:10.2307/2409766. JSTOR 2409766. 
  206. ^ Herrel, A.; Huyghe, K.; Vanhooydonck, B.; Backeljau, T.; Breugelmans, K.; Grbac, I.; Van Damme, R.; Irschick, D.J. (2008). "Rapid large-scale evolutionary divergence in morphology and performance associated with exploitation of a different dietary resource". Proceedings of the National Academy of Sciences 105 (12): 4792–5. Bibcode 2008PNAS..105.4792H. doi:10.1073/pnas.0711998105. PMC 2290806. PMID 18344323. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2290806. 
  207. ^ Losos, J.B. Warhelt, K.I. Schoener, T.W. (1997). "Adaptive differentiation following experimental island colonization in Anolis lizards". Nature 387 (6628): 70–3. Bibcode 1997Natur.387...70L. doi:10.1038/387070a0. 
  208. ^ Hoskin CJ, Higgle M, McDonald KR, Moritz C (2005). "Reinforcement drives rapid allopatric speciation". Nature 437 (7063): 1353–356. Bibcode 2005Natur.437.1353H. doi:10.1038/nature04004. PMID 16251964. 
  209. ^ Templeton AR (1 April 1980). "The theory of speciation via the founder principle". Genetics 94 (4): 1011–38. PMC 1214177. PMID 6777243. http://www.genetics.org/cgi/reprint/94/4/1011. 
  210. ^ Antonovics J (2006). "Evolution in closely adjacent plant populations X: long-term persistence of prereproductive isolation at a mine boundary". Heredity 97 (1): 33–7. doi:10.1038/sj.hdy.6800835. PMID 16639420. http://www.nature.com/hdy/journal/v97/n1/full/6800835a.html. 
  211. ^ Nosil P, Crespi B, Gries R, Gries G (2007). "Natural selection and divergence in mate preference during speciation". Genetica 129 (3): 309–27. doi:10.1007/s10709-006-0013-6. PMID 16900317. 
  212. ^ Savolainen V, Anstett M-C, Lexer C, Hutton I, Clarkson JJ, Norup MV, Powell MP, Springate D, Salamin N, Baker WJr (2006). "Sympatric speciation in palms on an oceanic island". Nature 441 (7090): 210–3. Bibcode 2006Natur.441..210S. doi:10.1038/nature04566. PMID 16467788. 
    *Barluenga M, Stölting KN, Salzburger W, Muschick M, Meyer A (2006). "Sympatric speciation in Nicaraguan crater lake cichlid fish". Nature 439 (7077): 719–23. Bibcode 2006Natur.439..719B. doi:10.1038/nature04325. PMID 16467837. 
  213. ^ Gavrilets S (2006). "The Maynard Smith model of sympatric speciation". J. Theor. Biol. 239 (2): 172–82. doi:10.1016/j.jtbi.2005.08.041. PMID 16242727. 
  214. ^ Wood TE, Takebayashi N, Barker MS, Mayrose I, Greenspoon PB, Rieseberg LH (2009). "The frequency of polyploid speciation in vascular plants". Proc. Natl. Acad. Sci. U.S.A. 106 (33): 13875–9. Bibcode 2009PNAS..10613875W. doi:10.1073/pnas.0811575106. PMC 2728988. PMID 19667210. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2728988. 
  215. ^ Hegarty Mf, Hiscock SJ (2008). "Genomic clues to the evolutionary success of polyploid plants". Current Biology 18 (10): 435–44. doi:10.1016/j.cub.2008.03.043. PMID 18492478. 
  216. ^ Jakobsson M, Hagenblad J, Tavaré S (2006). "A unique recent origin of the allotetraploid species Arabidopsis suecica: Evidence from nuclear DNA markers". Mol. Biol. Evol. 23 (6): 1217–31. doi:10.1093/molbev/msk006. PMID 16549398. 
  217. ^ Säll T, Jakobsson M, Lind-Halldén C, Halldén C (2003). "Chloroplast DNA indicates a single origin of the allotetraploid Arabidopsis suecica". J. Evol. Biol. 16 (5): 1019–29. doi:10.1046/j.1420-9101.2003.00554.x. PMID 14635917. 
  218. ^ Bomblies K, Weigel D (2007). "Arabidopsis-a model genus for speciation". Curr Opin Genet Dev 17 (6): 500–4. doi:10.1016/j.gde.2007.09.006. PMID 18006296. 
  219. ^ Sémon M, Wolfe KH (2007). "Consequences of genome duplication". Curr Opin Genet Dev 17 (6): 505–12. doi:10.1016/j.gde.2007.09.007. PMID 18006297. 
  220. ^ Niles Eldredge and Stephen Jay Gould, 1972. "Punctuated equilibria: an alternative to phyletic gradualism" In T.J.M. Schopf, ed., Models in Paleobiology. San Francisco: Freeman Cooper. pp. 82–115. Reprinted in N. Eldredge Time frames. Princeton: Princeton Univ. Press. 1985
  221. ^ Gould SJ (1994). "Tempo and mode in the macroevolutionary reconstruction of Darwinism". Proc. Natl. Acad. Sci. U.S.A. 91 (15): 6764–71. Bibcode 1994PNAS...91.6764G. doi:10.1073/pnas.91.15.6764. PMC 44281. PMID 8041695. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=44281. 
  222. ^ Benton MJ (1995). "Diversification and extinction in the history of life". Science 268 (5207): 52–8. Bibcode 1995Sci...268...52B. doi:10.1126/science.7701342. PMID 7701342. 
  223. ^ Raup DM (1986). "Biological extinction in Earth history". Science 231 (4745): 1528–33. Bibcode 1986Sci...231.1528R. doi:10.1126/science.11542058. PMID 11542058. 
  224. ^ Avise JC, Hubbell SP, Ayala FJ. (2008). "In the light of evolution II: Biodiversity and extinction". Proc. Natl. Acad. Sci. U.S.A. 105 (Suppl 1): 11453–7. Bibcode 2008PNAS..10511453A. doi:10.1073/pnas.0802504105. PMC 2556414. PMID 18695213. http://www.pnas.org/content/105/suppl.1/11453.full. 
  225. ^ a b c Raup DM (1994). "The role of extinction in evolution". Proc. Natl. Acad. Sci. U.S.A. 91 (15): 6758–63. Bibcode 1994PNAS...91.6758R. doi:10.1073/pnas.91.15.6758. PMC 44280. PMID 8041694. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=44280. 
  226. ^ Novacek MJ, Cleland EE (2001). "The current biodiversity extinction event: scenarios for mitigation and recovery". Proc. Natl. Acad. Sci. U.S.A. 98 (10): 5466–70. Bibcode 2001PNAS...98.5466N. doi:10.1073/pnas.091093698. PMC 33235. PMID 11344295. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=33235. 
  227. ^ Pimm S, Raven P, Peterson A, Sekercioglu CH, Ehrlich PR (2006). "Human impacts on the rates of recent, present and future bird extinctions". Proc. Natl. Acad. Sci. U.S.A. 103 (29): 10941–6. Bibcode 2006PNAS..10310941P. doi:10.1073/pnas.0604181103. PMC 1544153. PMID 16829570. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1544153. 
    *Barnosky AD, Koch PL, Feranec RS, Wing SL, Shabel AB (2004). "Assessing the causes of late Pleistocene extinctions on the continents". Science 306 (5693): 70–5. Bibcode 2004Sci...306...70B. doi:10.1126/science.1101476. PMID 15459379. 
  228. ^ Lewis OT (2006). "Climate change, species-area curves and the extinction crisis". Philos. Trans. R. Soc. Lond., B, Biol. Sci. 361 (1465): 163–71. doi:10.1098/rstb.2005.1712. PMC 1831839. PMID 16553315. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1831839. 
  229. ^ Jablonski D (2001). "Lessons from the past: evolutionary impacts of mass extinctions". Proc. Natl. Acad. Sci. U.S.A. 98 (10): 5393–8. Bibcode 2001PNAS...98.5393J. doi:10.1073/pnas.101092598. PMC 33224. PMID 11344284. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=33224. 
  230. ^ Doolittle, W. Ford (February 2000). "Uprooting the tree of life". Scientific American 282 (6): 90–95. doi:10.1038/scientificamerican0200-90. 
  231. ^ Peretó J (2005). "Controversies on the origin of life". Int. Microbiol. 8 (1): 23–31. PMID 15906258. http://www.im.microbios.org/0801/0801023.pdf. 
  232. ^ Joyce GF (2002). "The antiquity of RNA-based evolution". Nature 418 (6894): 214–21. doi:10.1038/418214a. PMID 12110897. 
  233. ^ Trevors JT, Psenner R (2001). "From self-assembly of life to present-day bacteria: a possible role for nanocells". FEMS Microbiol. Rev. 25 (5): 573–82. doi:10.1111/j.1574-6976.2001.tb00592.x. PMID 11742692. 
  234. ^ Theobald, DL. (2010). "A formal test of the theory of universal common ancestry". Nature 465 (7295): 219–22. Bibcode 2010Natur.465..219T. doi:10.1038/nature09014. PMID 20463738. 
  235. ^ Bapteste E, Walsh DA (2005). "Does the 'Ring of Life' ring true?". Trends Microbiol. 13 (6): 256–61. doi:10.1016/j.tim.2005.03.012. PMID 15936656. 
  236. ^ Darwin, Charles (1859). On the Origin of Species (1st ed.). London: John Murray. p. 1. ISBN 0-8014-1319-2. http://darwin-online.org.uk/content/frameset?itemID=F373&viewtype=text&pageseq=16. 
  237. ^ Doolittle WF, Bapteste E (2007). "Pattern pluralism and the Tree of Life hypothesis". Proc. Natl. Acad. Sci. U.S.A. 104 (7): 2043–9. Bibcode 2007PNAS..104.2043D. doi:10.1073/pnas.0610699104. PMC 1892968. PMID 17261804. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1892968. 
  238. ^ Kunin V, Goldovsky L, Darzentas N, Ouzounis CA (2005). "The net of life: reconstructing the microbial phylogenetic network". Genome Res. 15 (7): 954–9. doi:10.1101/gr.3666505. PMC 1172039. PMID 15965028. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1172039. 
  239. ^ Jablonski D (1999). "The future of the fossil record". Science 284 (5423): 2114–16. doi:10.1126/science.284.5423.2114. PMID 10381868. 
  240. ^ Mason SF (1984). "Origins of biomolecular handedness". Nature 311 (5981): 19–23. Bibcode 1984Natur.311...19M. doi:10.1038/311019a0. PMID 6472461. 
  241. ^ Wolf YI, Rogozin IB, Grishin NV, Koonin EV (2002). "Genome trees and the tree of life". Trends Genet. 18 (9): 472–79. doi:10.1016/S0168-9525(02)02744-0. PMID 12175808. 
  242. ^ Varki A, Altheide TK (2005). "Comparing the human and chimpanzee genomes: searching for needles in a haystack". Genome Res. 15 (12): 1746–58. doi:10.1101/gr.3737405. PMID 16339373. 
  243. ^ Ciccarelli FD, Doerks T, von Mering C, Creevey CJ, Snel B, Bork P (2006). "Toward automatic reconstruction of a highly resolved tree of life". Science 311 (5765): 1283–87. Bibcode 2006Sci...311.1283C. doi:10.1126/science.1123061. PMID 16513982. 
  244. ^ a b Cavalier-Smith T (2006). "Cell evolution and Earth history: stasis and revolution". Philos Trans R Soc Lond B Biol Sci 361 (1470): 969–1006. doi:10.1098/rstb.2006.1842. PMC 1578732. PMID 16754610. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1578732. 
  245. ^ Schopf J (2006). "Fossil evidence of Archaean life". Philos Trans R Soc Lond B Biol Sci 361 (1470): 869–85. doi:10.1098/rstb.2006.1834. PMC 1578735. PMID 16754604. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1578735. 
    *Altermann W, Kazmierczak J (2003). "Archean microfossils: a reappraisal of early life on Earth". Res Microbiol 154 (9): 611–17. doi:10.1016/j.resmic.2003.08.006. PMID 14596897. 
  246. ^ Schopf J (1994). "Disparate rates, differing fates: tempo and mode of evolution changed from the Precambrian to the Phanerozoic". Proc Natl Acad Sci U S A 91 (15): 6735–42. Bibcode 1994PNAS...91.6735S. doi:10.1073/pnas.91.15.6735. PMC 44277. PMID 8041691. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=44277. 
  247. ^ Poole A, Penny D (2007). "Evaluating hypotheses for the origin of eukaryotes". Bioessays 29 (1): 74–84. doi:10.1002/bies.20516. PMID 17187354. 
  248. ^ Dyall S, Brown M, Johnson P (2004). "Ancient invasions: from endosymbionts to organelles". Science 304 (5668): 253–57. Bibcode 2004Sci...304..253D. doi:10.1126/science.1094884. PMID 15073369. 
  249. ^ Martin W (2005). "The missing link between hydrogenosomes and mitochondria". Trends Microbiol. 13 (10): 457–59. doi:10.1016/j.tim.2005.08.005. PMID 16109488. 
  250. ^ Lang B, Gray M, Burger G (1999). "Mitochondrial genome evolution and the origin of eukaryotes". Annu Rev Genet 33 (1): 351–97. doi:10.1146/annurev.genet.33.1.351. PMID 10690412. 
    *McFadden G (1999). "Endosymbiosis and evolution of the plant cell". Curr Opin Plant Biol 2 (6): 513–19. doi:10.1016/S1369-5266(99)00025-4. PMID 10607659. 
  251. ^ DeLong E, Pace N (2001). "Environmental diversity of bacteria and archaea". Syst Biol 50 (4): 470–8. doi:10.1080/106351501750435040. PMID 12116647. 
  252. ^ Kaiser D (2001). "Building a multicellular organism". Annu. Rev. Genet. 35 (1): 103–23. doi:10.1146/annurev.genet.35.102401.090145. PMID 11700279. 
  253. ^ Valentine JW, Jablonski D, Erwin DH (1 March 1999). "Fossils, molecules and embryos: new perspectives on the Cambrian explosion". Development 126 (5): 851–9. PMID 9927587. http://dev.biologists.org/cgi/reprint/126/5/851. 
  254. ^ Ohno S (1997). "The reason for as well as the consequence of the Cambrian explosion in animal evolution". J. Mol. Evol.. 44 1 (S1): S23–7. doi:10.1007/PL00000055. PMID 9071008. 
    *Valentine J, Jablonski D (2003). "Morphological and developmental macroevolution: a paleontological perspective". Int. J. Dev. Biol. 47 (7–8): 517–22. PMID 14756327. http://www.ijdb.ehu.es/web/paper.php?doi=14756327. 
  255. ^ Waters ER (2003). "Molecular adaptation and the origin of land plants". Mol. Phylogenet. Evol. 29 (3): 456–63. doi:10.1016/j.ympev.2003.07.018. PMID 14615186. 
  256. ^ Mayhew PJ (2007). "Why are there so many insect species? Perspectives from fossils and phylogenies". Biol Rev Camb Philos Soc 82 (3): 425–54. doi:10.1111/j.1469-185X.2007.00018.x. PMID 17624962. 
  257. ^ Carroll RL (2007). "The Palaeozoic Ancestry of Salamanders, Frogs and Caecilians". Zool J Linn Soc 150 (s1): 1–140. doi:10.1111/j.1096-3642.2007.00246.x. PMID 12752770. 
  258. ^ Wible JR, Rougier GW, Novacek MJ, Asher RJ (2007). "Cretaceous eutherians and Laurasian origin for placental mammals near the K/T boundary". Nature 447 (7147): 1003–1006. doi:10.1038/nature05854. PMID 17581585. 
  259. ^ Witmer LM (2011). "Palaeontology: An icon knocked from its perch". Nature 475 (7357): 458–459. doi:10.1038/475458a. PMID 21796198. 
  260. ^ Bull JJ, Wichman HA (2001). "Applied evolution". Annu Rev Ecol Syst 32 (1): 183–217. doi:10.1146/annurev.ecolsys.32.081501.114020. 
  261. ^ Doebley JF, Gaut BS, Smith BD (2006). "The molecular genetics of crop domestication". Cell 127 (7): 1309–21. doi:10.1016/j.cell.2006.12.006. PMID 17190597. 
  262. ^ Jäckel C, Kast P, Hilvert D (2008). "Protein design by directed evolution". Annu Rev Biophys 37 (1): 153–73. doi:10.1146/annurev.biophys.37.032807.125832. PMID 18573077. 
  263. ^ Maher B. (2009). "Evolution: Biology's next top model?". Nature 458 (7239): 695–8. doi:10.1038/458695a. PMID 19360058. 
  264. ^ Borowsky R (2008). "Restoring sight in blind cavefish". Curr. Biol. 18 (1): R23–4. doi:10.1016/j.cub.2007.11.023. PMID 18177707. 
  265. ^ Gross JB, Borowsky R, Tabin CJ (2009). Barsh, Gregory S.. ed. "A novel role for Mc1r in the parallel evolution of depigmentation in independent populations of the cavefish Astyanax mexicanus". PLoS Genet. 5 (1): e1000326. doi:10.1371/journal.pgen.1000326. PMC 2603666. PMID 19119422. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2603666. 
  266. ^ Fraser AS (1958). "Monte Carlo analyses of genetic models". Nature 181 (4603): 208–9. Bibcode 1958Natur.181..208F. doi:10.1038/181208a0. PMID 13504138. 
  267. ^ Rechenberg, Ingo (1973) (in German). Evolutionsstrategie – Optimierung technischer Systeme nach Prinzipien der biologischen Evolution (PhD thesis). Fromman-Holzboog. 
  268. ^ Holland, John H. (1975). Adaptation in Natural and Artificial Systems. University of Michigan Press. ISBN 0-262-58111-6. 
  269. ^ Koza, John R. (1992). Genetic Programming. MIT Press. ISBN 0-262-11170-5. 
  270. ^ Jamshidi M (2003). "Tools for intelligent control: fuzzy controllers, neural networks and genetic algorithms". Philosophical transactions. Series A, Mathematical, physical and engineering sciences 361 (1809): 1781–808. Bibcode 2003RSPTA.361.1781J. doi:10.1098/rsta.2003.1225. PMID 12952685. 
  271. ^ Browne, Janet (2003). Charles Darwin: The Power of Place. London: Pimlico. pp. 376–379. ISBN 0-7126-6837-3. 
  272. ^ For an overview of the philosophical, religious and cosmological controversies, see: Dennett, D (1995). Darwin's Dangerous Idea: Evolution and the Meanings of Life. Simon & Schuster. ISBN 978-0-684-82471-0. 
    *For the scientific and social reception of evolution in the 19th and early 20th centuries, see: Johnston, Ian C.. "History of Science: Origins of Evolutionary Theory". And Still We Evolve. Liberal Studies Department, Malaspina University College. http://records.viu.ca/~johnstoi/darwin/sect3.htm. Retrieved 2007-05-24. 
    *Bowler, PJ (2003). Evolution: The History of an Idea, Third Edition, Completely Revised and Expanded. University of California Press. ISBN 978-0-520-23693-6. 
    *Zuckerkandl E (2006). "Intelligent design and biological complexity". Gene 385: 2–18. doi:10.1016/j.gene.2006.03.025. PMID 17011142. 
  273. ^ Ross, M.R. (2005). "Who Believes What? Clearing up Confusion over Intelligent Design and Young-Earth Creationism". Journal of Geoscience Education 53 (3): 319. http://www.nagt.org/files/nagt/jge/abstracts/Ross_v53n3p319.pdf. Retrieved 2008-04-28. 
  274. ^ Hameed, Salman (2008-12-12). "Science and Religion: Bracing for Islamic Creationism". Science 322 (5908): 1637–1638. doi:10.1126/science.1163672. PMID 19074331. http://helios.hampshire.edu/~sahCS/Hameed-Science-Creationism.pdf. Retrieved 2009. 
  275. ^ Bowler, Peter J. (2003). Evolution:The History of an Idea. University of California Press. ISBN 0-520-23693-9. 
  276. ^ Spergel D. N.; Scott, EC; Okamoto, S (2006). "Science communication. Public acceptance of evolution". Science 313 (5788): 765–66. doi:10.1126/science.1126746. PMID 16902112. 
  277. ^ Spergel, D. N.; Verde, L.; Peiris, H. V.; Komatsu, E.; Nolta, M. R.; Bennett, C. L.; Halpern, M.; Hinshaw, G. et al. (2003). "First-Year Wilkinson Microwave Anisotropy Probe (WMAP) Observations: Determination of Cosmological Parameters". The Astrophysical Journal Supplement Series 148 (1): 175–94. arXiv:astro-ph/0302209. Bibcode 2003ApJS..148..175S. doi:10.1086/377226. 
  278. ^ Wilde SA, Valley JW, Peck WH, Graham CM (2001). "Evidence from detrital zircons for the existence of continental crust and oceans on the Earth 4.4 Gyr ago". Nature 409 (6817): 175–78. doi:10.1038/35051550. PMID 11196637. 
  279. ^ Branch, Glenn (March 2007). "Understanding Creationism after Kitzmiller". BioScience (American Institute of Biological Sciences) 57 (3): 278–284. doi:10.1641/B570313. http://www.bioone.org/doi/full/10.1641/B570313. Retrieved 13 November 2011. 

Further reading

Introductory reading
History of evolutionary thought
Advanced reading

External links

General information

History of evolutionary thought

On-line lectures

v · Biology
Subdisciplines of Biology Biology organism collage.png
Hierarchy of Life
Foundations of Biology
Principles of Evolution
Principles of Ecology
Principles of Molecular Biology
Principles of Biochemistry
Glossaries
v · d · e Basic topics in evolutionary biology
Processes of evolution
Population genetic mechanisms
Evolutionary developmental
biology (Evo-devo) concepts
Evolution of organs
and biological processes
Aging · Avian flight · Cellular · DNA · Eye · Flagella · Hair · Human intelligence · Mammalian auditory ossicles · Mosaic evolution · Multicellular · Nervous Systems · Sex
Taxa evolution
Birds · Butterflies · Cats · Cephalopods · Dinosaurs · Dogs · Dolphins and whales · Fish · Fungi · Horses · Humans · Influenza · Insects · Lemur · Life · Mammals · Molluscs · Plants · Reptiles · Sirenians (sea cows) · Spiders · Viruses
Modes of speciation
History of evolutionary thought
Other subfields


Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?
Synonyms:
, , , , / , , , / , / / , (of a curve)


Look at other dictionaries:

  • ÉVOLUTION — Le terme évolution a désigné et désigne encore plusieurs concepts; il sera pris ici dans le sens d’évolution biologique, défini précisément plus loin. Dans cette acception, il est d’un emploi relativement récent. Ni Lamarck ni Darwin ne s’en sont …   Encyclopédie Universelle

  • Evolution —     Evolution (History and Scientific Foundation)     † Catholic Encyclopedia ► Evolution (History and Scientific Foundation)     The world of organisms comprises a great system of individual forms generally classified according to structural… …   Catholic encyclopedia

  • Evolution — ist die Veränderung der vererbbaren Merkmale einer Population von Lebewesen von Generation zu Generation. Diese Merkmale sind in Form von Genen kodiert, die bei der Fortpflanzung kopiert und an den Nachwuchs weitergegeben werden. Durch Mutationen …   Deutsch Wikipedia

  • Evolution — Évolution Cette page d’homonymie répertorie les différents sujets et articles partageant un même nom …   Wikipédia en Français

  • Evolution — Saltar a navegación, búsqueda Evolution puede referirse a: Evolution (película), una película dirigida por Ivan Reitman. Evolution (software), antes conocido como Novell Evolution, un gestor de información personal y de trabajo en grupo para… …   Wikipedia Español

  • Evolution — Почтовый клиент …   Википедия

  • Evolution — Sf Entwicklung erw. fach. (18. Jh.) Entlehnung. Unter dem Einfluß von frz. évolution entlehnt aus l. ēvolūtio das Aufrollen, Aufwickeln (einer Buchrolle) , zu l. ēvolvere (ēvolūtum) auseinanderwickeln, entwickeln , zu l. volvere drehen, rollen… …   Etymologisches Wörterbuch der deutschen sprache

  • Evolution — Ev o*lu tion ([e^]v [ o]*l[=u] sh[u^]n), n. [L. evolutio an unrolling: cf. F. [ e]volution evolution. See {Evolve}.] 1. The act of unfolding or unrolling; hence, any process of growth or development; as, the evolution of a flower from a bud, or… …   The Collaborative International Dictionary of English

  • evolution — UK US /ˌiːvəˈluːʃən/ noun [U or C] ► a gradual process of change and development: the evolution of sth »The evolution of modern management began in the last decades of the nineteenth century. evolution from sth to/into sth »As CEO he has overseen …   Financial and business terms

  • evolution —     Evolution generally describes any gradual process of change. It is used more specifically to describe any theory that explains biological diversity through gradual change derived from initial commonality. There have been many theories of this …   Christian Philosophy

  • evolution — 1620s, an opening of what was rolled up, from L. evolutionem (nom. evolutio) unrolling (of a book), noun of action from evolvere (see EVOLVE (Cf. evolve)). Used in various senses in medicine, mathematics, and general use, including growth to… …   Etymology dictionary

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”