Lysergamides

Lysergamides

Amides of lysergic acid are collectively known as lysergamides.[1][2][3]

General structure of Lysergamides

Lysergamides, tabulated by structure

Name R1 R6 R2 R3
LSA / LAA H CH3 H H
DAM-57 H CH3 CH3 CH3
Ergonovine H CH3 CH(CH3)CH2OH H
Methergine H CH3 CH(CH2CH3)CH2OH H
Methysergide CH3 CH3 CH(CH2CH3)CH2OH H
LAE-32 H CH3 CH2CH3 H
LSB H CH3 CH(CH3)CH2CH3 H
LSP H CH3 CH(CH2CH3)CH2CH3 H
DAL H CH3 H2C=CH-CH2 H2C=CH-CH2
MIPLA H CH3 CH(CH3)2 CH3
EIPLA H CH3 CH(CH3)2 CH2CH3
LAMP H CH3 CH2CH2CH3 CH3
LSD / LAD H CH3 CH2CH3 CH2CH3
ETH-LAD H CH2CH3 CH2CH3 CH2CH3
PARGY-LAD H HC≡C−CH2 CH2CH3 CH2CH3
AL-LAD H H2C=CH-CH2 CH2CH3 CH2CH3
PRO-LAD H CH2CH2CH3 CH2CH3 CH2CH3
CYP-LAD H C3H5 CH2CH3 CH2CH3
BU-LAD H CH2CH2CH2CH3 CH2CH3 CH2CH3
ALD-52 COCH3 CH3 CH2CH3 CH2CH3
MLD-41 CH3 CH3 CH2CH3 CH2CH3
LSM-775 H CH3 CH2CH2-O-CH2CH2
LPD-824 H CH3 CH2CH2 CH2CH2
LSD-Pip H CH3 CH2CH2 CH2CH2CH2
LA-SS-Az H CH3 CH2(CHCH3)2CH2

References

  1. ^ Hofmann A. Psychotomimetic Drugs: Chemical and Pharmacological Aspects. Acta. Physiol. Pharmacol. Neerlandica. 1959;8:240-258.
  2. ^ US patent 2997470, Richard P. Pioch, "LYSERGIC ACID AMIDES", published 1956-03-05, issued 1961-08-22 
  3. ^ David E. Nichols. LSD and Its Lysergamide Cousins. The Heffter Review of Psychedelic Research. 2001;2:80-87.

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