Ergonovine

Ergonovine

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IUPAC_name = (6a"R",9"R")-"N"-(("S")-1-hydroxypropan-2-yl)- 7-methyl-4,6,6a,7,8,9-hexahydroindolo [4,3-"fg"] quinoline-9-carboxamide
CAS_number = 478-94-4
PubChem = 443884
C=19 | H=23 | N=3 | O=2
molecular_weight = 325.41 g/mol
synonyms = Ergonovine, Lysergic acid beta-propanolamide
metabolism = hepatic
excretion = renal
legal_AU =
legal_CA =
legal_UK =
legal_US = List I precursor
legal_status =
routes_of_administration =

Ergonovine, also known as ergometrine or d-lysergic acid beta-propanolamide, is an ergoline (and lysergamide) derivative, and one of the primary ergot and morning glory alkaloids . It is chemically similar to LSD, ergine, and lysergic acid.

Medical use

It has a medical use in obstetrics to facilitate delivery of the placenta and to prevent bleeding after childbirth by causing smooth muscle tissue in the blood vessel walls to narrow, thereby reducing blood flow. It is usually combined with oxytocin (syntocinon) as syntometrine.

Recreational use

According to [http://www.erowid.org/library/books_online/tihkal/tihkal26.shtml TIHKAL] by Alexander Shulgin, ergonovine has LSD-like action at levels of 2-10 milligrams. Clinical dosages are about ten times lower.

Legal status

Ergometrine is listed as Table I precursors under the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances, as possible precursor compound for LSD. [http://www.incb.org/pdf/e/list/red.pdf http://www.incb.org/pdf/e/list/red.pdf] ]

References


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  • ergonovine — ☆ ergonovine [ʉr΄gō nō′vēn΄, ʉr΄gō nō′vin ] n. [ergo (< Fr < ergot, ERGOT) + nov (< L novus, NEW) + INE3] a water soluble alkaloid of ergot, C19H23N3O2, used to increase contraction of the uterus during childbirth and prevent uterine… …   English World dictionary

  • Ergonovine — Ergométrine Ergométrine Structure de l ergométrine Général No CAS …   Wikipédia en Français

  • ergonovine maleate — [USP] the bimaleate salt of ergonovine; used as an oxytocic in the prevention or treatment of postpartum or postabortion hemorrhage, administered orally, intramuscularly, or intravenously. It is also used intravenously as a provocative test in… …   Medical dictionary

  • ergonovine — noun Etymology: ergo + Latin novus new more at new Date: circa 1936 an alkaloid C19H23N3O2 derived from ergot and used especially in the form of its maleate as an oxytocic …   New Collegiate Dictionary

  • ergonovine — /err geuh noh veen, vin/, n. Pharm. an alkaloid, C23H27N3O2, obtained from ergot or produced synthetically, used chiefly in obstetrics to induce uterine contractions or control uterine bleeding. [1935 40; ERGO 2 + nov ( < L novus NEW) + INE2] * * …   Universalium

  • ergonovine — noun Ergometrine …   Wiktionary

  • ergonovine — An alkaloid from ergot; on hydrolysis it yields d lysergic acid and l 2 aminopropanol; stimulates uterine contractions. SYN: ergobasine, ergometrine, ergostetrine. e. maleate a powerful oxytocic agent; this action is more prominent …   Medical dictionary

  • ergonovine — n. medication used to treat bleeding after childbirth or miscarriage (Medicine) …   English contemporary dictionary

  • ergonovine — er·go·no·vine …   English syllables

  • ergonovine — er•go•no•vine [[t]ˌɜr gəˈnoʊ vin, vɪn[/t]] n. pha an alkaloid, C23H27N3O2, obtained from ergot or produced synthetically, used chiefly in obstetrics to induce uterine contractions or control uterine bleeding • Etymology: 1935–40; ergo II+ L… …   From formal English to slang

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