Chemotherapy regimens

Chemotherapy regimens

A fundamental philosophy of combination cancer therapy is that different drugs work through different cytotoxic mechanisms. Because they have different dose-limiting adverse effects, they can be given together at full doses in chemotherapy regimens.[1]

The term "induction regimen" refers to a chemotherapy regimen which is used for the initial treatment of a disease.

Chemotherapy regimens are often identified by acronyms, identifying the agents used in combination. However, the letters used are not consistent across regimens, and in some cases (for example, "BEACOPP") the same letter combination is used to represent two different treatments: there is not a naming standard for chemotherapy regimens. This page merely lists commonly used conventions.

Name Components Example of uses, and other notes
ABVD Adriamycin (doxorubicin), bleomycin, vinblastine, dacarbazine Hodgkin's lymphoma
AC Adriamycin (doxorubicin), cyclophosphamide Breast cancer
BEACOPP Bleomycin, etoposide, Adriamycin (doxorubicin), cyclophosphamide, Oncovin (vincristine), procarbazine, prednisone Hodgkin's lymphoma
BEP Bleomycin, etoposide, platinum agent (cisplatin) Testicular cancer, germ cell tumors
CA Cyclophosphamide, Adriamycin (doxorubicin) (same as AC) Breast cancer
CAF Cyclophosphamide, Adriamycin (doxorubicin), fluorouracil (5-FU) Breast cancer
CAV Cyclophosphamide, Adriamycin (doxorubicin), vincristine Lung cancer
CBV Cyclophosphamide, BCNU (carmustine), VP-16 (etoposide) Lymphoma
ChlVPP/EVA Chlorambucil, vincristine (Oncovin), procarbazine, prednisone, etoposide, vinblastine, Adriamycin (doxorubicin) Hodgkin's lymphoma
CHOP Cyclophosphamide, hydroxydoxorubicin (doxorubicin), vincristine (Oncovin), prednisone Non-Hodgkin lymphoma
CHOP-R or R-CHOP CHOP + rituximab B cell non-Hodgkin lymphoma
COP or CVP Cyclophosphamide, Oncovin (vincristine), prednisone Non-Hodgkin lymphoma in patients with history of cardiovascular disease
CMF Cyclophosphamide, methotrexate, fluorouracil (5-FU) Breast cancer
COPP Cyclophosphamide, Oncovin (vincristine), procarbazine, prednisone Non-Hodgkin lymphoma
EC Epirubicin, cyclophosphamide Breast cancer
ECF Epirubicin, cisplatin, fluorouracil (5-FU) Gastric cancer and oesophageal cancer
EP Etoposide, platinum agent (cisplatin) Testicular cancer, germ cell tumors
EPOCH Etoposide, prednisone, Oncovin, cyclophosphamide, and hydroxydaunorubicin Lymphomas
FEC Fluorouracil (5-FU), epirubicin, cyclophosphamide Breast cancer
FL (Also known as Mayo) Fluorouracil (5-FU), leucovorin (folinic acid) Colorectal cancer
FOLFOX Fluorouracil (5-FU), leucovorin (folinic acid), oxaliplatin Colorectal cancer
FOLFIRI Fluorouracil (5-FU), leucovorin (folinic acid), irinotecan Colorectal cancer
ICE ifosfamide, carboplatin, etoposide (VP-16) Aggressive lymphomas, progressive neuroblastoma
ICE-R ICE + rituximab High-risk progressive or recurrent lymphomas
m-BACOD Methotrexate, bleomycin, Adriamycin (doxorubicin), cyclophosphamide, Oncovin (vincristine), dexamethasone Non-Hodgkin lymphoma
MACOP-B Methotrexate, leucovorin (folinic acid), Adriamycin (doxorubicin), cyclophosphamide, Oncovin (vincristine), prednisone, bleomycin Non-Hodgkin lymphoma
MOPP Mechlorethamine, Oncovin (vincristine), procarbazine, prednisone Hodgkin's lymphoma
MVAC methotrexate, vinblastine, adriamycin, cisplatin Advanced bladder cancer[2]
PCV Procarbazine, CCNU (lomustine), vincristine Brain tumors
ProMACE-MOPP Methotrexate, Adriamycin (doxorubicin), cyclophosphamide, etoposide + MOPP Non-Hodgkin lymphoma
ProMACE-CytaBOM Prednisone, doxorubicin (adriamycin), cyclophosphamide, etoposide, cytarabine, bleomycin, Oncovin (vincristine), methotrexate, leucovorin Non-Hodgkin lymphoma
R-FCM Rituximab, fludarabine, cyclophosphamide, mitoxantrone B cell non-Hodgkin lymphoma
Stanford V Doxorubicin, mechlorethamine, bleomycin, vinblastine, vincristine, etoposide, prednisone Hodgkin's lymphoma
Thal/Dex Thalidomide, dexamethasone Multiple myeloma
TIP Paclitaxel, ifosfamide, platinum agent cisplatin Testicular cancer, germ cell tumors in salvage therapy
VAC Vincristine, Actinomycin, Cyclophosphamide Rhabdomyosarcoma
VAD Vincristine, Adriamycin (doxorubicin), dexamethasone Multiple myeloma
VAMP Vincristine and others Hodgkin's lymphoma, leukemia, multiple myeloma
VAPEC-B Vincristine, Adriamycin (doxorubicin), prednisone, etoposide, cyclophosphamide, bleomycin Hodgkin's lymphoma
VIP Vinblastin, ifosfamide, platinum agent cisplatin Testicular cancer, germ cell tumors

See also

References

  1. ^ Mayer, RJ, Targeted therapy for advanced colorectal cancer -- more is not always better, N Engl J Med. 2009;360:623
  2. ^ http://www.cancernetwork.com/bladder-cancer/content/article/10165/71963

External links


Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Chemotherapy-induced nausea and vomiting — (CINV) is a common side effect of many cancer treatments. Nausea and vomiting are two of the most feared cancer treatment related side effects for cancer patients and their families. In 1983, Coates et al. found that patients receiving… …   Wikipedia

  • Chemotherapy — A woman being treated with docetaxel chemotherapy for breast cancer. Cold mittens and wine coolers are placed on her hands and feet to reduce harm to her nails. Chemotherapy (sometimes cancer chemotherapy) is the treatment of cancer with an… …   Wikipedia

  • Breast cancer chemotherapy — refers to the use of cytotoxic drugs (chemotherapy) in the treatment of breast cancer. Types Chemotherapy can be given both before and after surgery. Neoadjuvant chemotherapy is used to shrink the size of a tumor prior to surgery. Adjuvant… …   Wikipedia

  • History of cancer chemotherapy — The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs. Cancer drug development has exploded since then into a multi billion dollar industry. The targeted therapy revolution has… …   Wikipedia

  • Low-dose chemotherapy — is being studied/used in the treatment of cancer to avoid the devastating side effects of conventional chemotherapy. Historically, oncologists have used the highest possible dose that the body can tolerate in order to kill as many cancer cells as …   Wikipedia

  • Tuberculosis treatment — Various pharmaceutical tuberculosis treatments their actions Tuberculosis treatment refers to the medical treatment of the infectious disease tuberculosis (TB). The standard short course treatment for TB is isoniazid, rifampicin (also known as… …   Wikipedia

  • Multiple myeloma — Classification and external resources Micrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H E stain ICD …   Wikipedia

  • Breast cancer — Classification and external resources Mammograms showing a normal breast (left) and a cancerous breast (right). ICD 10 C …   Wikipedia

  • CHOP — is the acronym for a chemotherapy regimen used in the treatment of non Hodgkin lymphoma. CHOP stands for Cyclophosphamide, Hydroxydaunorubicin (Adriamycin), Oncovin (Vincristine), Prednisone/Prednisolone.Uses and indicationsCHOP consists of: *… …   Wikipedia

  • Colorectal cancer — Classification and external resources Diagram of the lower gastrointestinal tract ICD 10 C …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”