Fotemustine

Fotemustine

drugbox
IUPAC_name = diethyl (1-{ [(2-chloroethyl)(nitroso)carbamoyl] amino}
ethyl)phosphonate



CAS_number = 92118-27-9
ATC_prefix = L01
ATC_suffix = AD05
ATC_supplemental =
PubChem = 104799
DrugBank = EXPT03300
C = 9 | H = 19 | Cl = 1 | N = 3 | O = 5 | P = 1
molecular_weight = 315.691 g/mol
bioavailability =
protein_bound =
metabolism =
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US =
pregnancy_category =
legal_AU =
legal_UK =
legal_US =
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routes_of_administration =

Fotemustine is a nitrosourea alkylating agent that is being investigated for use in the treatment of melanoma. A recent study (cited below) has shown that fotemustine produces improved response rates and increased survival over dacarbazine in the treatment of disseminated cutaneous melanoma.

External links

* [http://jco.ascopubs.org/cgi/content/abstract/22/6/1118 Fotemustine vs. Dacarbazine for Disseminated Melanoma]


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