Nedaplatin

Nedaplatin

Systematic (IUPAC) name
Diammine[(hydroxy-κO)acetato(2-)-κO]platinum
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	IV
Identifiers
CAS number	95734-82-0
ATC code	None
PubChem	CID 6917890
UNII	8UQ3W6JXAN Y
KEGG	D01416 Y
Chemical data
Formula	C2H8N2O3Pt
Mol. mass	303.17 g/mol
SMILES	eMolecules & PubChem
Y(what is this?)  (verify)

Nedaplatin (INN, marketed under the tradename Aqupla) is a platinum compound which is used for cancer chemotherapy.^[1] It produces less nausea, vomiting and nephrotoxicity than other platinum-containing drugs.^[2]

References

1. ^ Wheate, Nial J.; Walker, Shonagh; Craig, Gemma E.; Oun, Rabbab (2010). "The status of platinum anticancer drugs in the clinic and in clinical trials". Dalton Transactions 39 (35): 8113–27. doi:10.1039/C0DT00292E. PMID 20593091. 
2. ^ Ota K (February 1996). "[Nedaplatin]" (in Japanese). Gan to Kagaku Ryoho 23 (3): 379–87. PMID 8712835. 

• (Japanese) Aqupla アクプラ (PDF) Shionogi & Co. March 2007.

External links

• (Japanese) Official Shionogi & Co. Website

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