Actinic elastosis

Actinic elastosis
Actinic elastosis
Classification and external resources
ICD-10 L57.8 (ILDS L57.890)

Actinic, or solar, elastosis is an accumulation of abnormal elastin (elastic tissue) in the dermis of the skin,[1] and in the conjunctiva of the eye,[2] which occurs as a result of the cumulative effects of prolonged and excessive sun exposure, a process known as photoaging.


Clinical features

Actinic elastosis usually appears as thickened, dry, wrinkled skin. Several clinical variants have been recorded. One of the most readily identifiable is the thickened, deeply fissured skin seen on the back of the chronically sun-exposed neck, known as cutis rhomboidalis nuchae.[1] These features are a part of the constellation of changes that are seen in photoaged skin.[1]

Causes / Aetiology

The origin of the elastotic material in the dermis remains a subject of debate. Theories on the formation of the elastotic material include actinic stimulation of fibroblasts, promoting synthesis of this material; or that the material is a degradation product of collagen, elastin or both.[1]


In the earlier stages of actinic elastosis, elastic fiber proliferation can be seen in the dermis. As the condition becomes more established, the collagen fibers of the papillary dermis and reticular dermis become increasingly replaced by thickened and curled fibers that form tangled masses and appear basophilic under routine haematoxylin and eosin staining. These fibers stain black with the Verhoeff stain.[1]


There are numerous treatment options for photoaged skin. These include dermabrasion, topical application of retinoic acid, carbon dioxide laser resurfacing, hyaluronic acid injection into the dermis, Imiquimod, tacrolimus ointment and topical oestrogen therapy. These treatments have variable efficacy.[1]

The most effective prevention strategy for photoaging remains minimization of sun-exposure through use of sunscreen and other sun exposure avoidance measures.[1]

See also


  1. ^ a b c d e f g Weedon, David (2010). Weedon's Skin Pathology, 3rd Edition. Elsevier. ISBN 978-0-7020-3485-5. 
  2. ^ Klintworth, G; Cummings, T. "24; The eye and ocular adnexa". In Stacey, Mills. Sternberg's Diagnostic Surgical Pathology (5 ed.). ISBN 978-0-7817-7942-5. 

Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • actinic elastosis — a type of photodamage to the skin seen especially in light skinned individuals, marked by inelasticity, thinning (or sometimes thickening), wrinkling, dryness with fine scaling, and variable hyperpigmentation or other blemishes. Called also… …   Medical dictionary

  • elastosis — 1. Degenerative change in elastic tissue. 2. Degeneration of collagen fibers, with altered staining properties resembling elastic tissue. SYN: elastoid degeneration (1), elastotic degeneration. e. colloidalis conglomerata SYN: colloid milium …   Medical dictionary

  • solar elastosis — actinic e …   Medical dictionary

  • senile elastosis — solar elastosis actinic e …   Medical dictionary

  • farmers' skin — actinic elastosis …   Medical dictionary

  • sailors' skin — actinic elastosis …   Medical dictionary

  • List of cutaneous conditions — This is an incomplete list, which may never be able to satisfy particular standards for completeness. You can help by expanding it with reliably sourced entries. See also: Cutaneous conditions, Category:Cutaneous conditions, and ICD 10… …   Wikipedia

  • Basal-cell carcinoma — Classification and external resources A basal cell carcinoma ICD 10 C44 (ILDS C44.L21) ICD 9 …   Wikipedia

  • Favre-Racouchot syndrome — a type of actinic elastosis usually seen in elderly men, in which giant comedones, pilosebaceous cysts, and large folds of furrowed and yellowish skin are seen in the periorbital region. Called also nodular elastosis or elastoidosis …   Medical dictionary

  • cutis rhomboidalis nuchae — a type of actinic elastosis on the back of the neck, in which the skin of the nape of the neck becomes thickened, tough, leathery, and furrowed, with a rhomboidal pattern …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”