Name = PAGENAME
ICD10 = D21, D25
ICD9 = ICD9|218
ICDO = 8890-8894
MeshID = D007889A leiomyoma (plural is 'leiomyomata') is a
benign smooth muscle neoplasmthat is not premalignant. They can occur in any organ, but the most common forms occur in the uterus, small boweland the esophagus.
**muV = (
myo) mouseor muscle
Uterine fibroids are leiomyomata of the uterine smooth muscle. As other leiomyomata, they are
benign, but may lead to excessive menstrual bleeding ( menorrhagia), often cause anemiaand may lead to infertility. Enucleation is removal of fibroids without removing the uterus ( hysterectomy), which is also commonly performed. Lasersurgery (called myolysis) is increasingly used, and provides a viable alternative to surgery.
Uterine leiomyomas originate in the
myometriumand are classified by location:
Submucosal– lie just beneaththe endometrium.
* – lie within the uterine
Subserosal– lie at the serosal surface of the uterus or may bulgeout from the myometriumand can become pedunculated.
Estrogen and progesterone usually stimulate their growth, and hormone suppression may hence decrease their size.
They are also the most common
benignesophageal tumour, though this accounts for less than 1% of esophageal neoplasms. The remainder consists mainly of carcinomas. Although the vast majority of benign esophageal tumors are clinically silent and go undetected, large or strategically located tumors may become symptomatic.cite web | author = James C. Chou, MD & Frank G. Gress, MD | title =Benign Esophageal Tumors | work =Esophageal Cancer Overview (Cancer of the Esophagus) | url=http://www.health.am/cr/benign-esophageal-tumors/ | publisher=Armenian Health Network, Health.am | accessdate=2007-03-21]
Leiomyoma of jejunum
Leiomyoma is the most common benign tumor of small bowel. Approximately 50% of cases are found in the jejunum, followed by the ileum in 31% of cases. Almost one half of all lesions are less than 5 centimeters.cite web | author = By Michael P. Buetow, M.D. | title =Leiomyoma of Jejunum | url=http://www.appliedradiology.com/case/case.asp?ID=88&SubCatID=97&CatID=43&ThreadID= | publisher=Applied Radiology Online | accessdate=2007-03-21]
Diagnosis depends on position of the myomas. Traditional Transabdominal or Transvaginal ultrasonogram can detect large submucosal and transmural myomas. For submucosal myomas saline infusion sonography is the best.
GnRH analogues for 3-6 months are used to reduce the size of the myomas. It usually reduce the size by 60% to 70%. But once the medication is stopped the myomas will grow back.
Myomectomyis a choice to remove myomas. It is usually done when the client wants to preserve their fertility.
Total Abdominal or Vaginal
hysterectomywith Bilateral Salpingo-oophorectomy is the definitive treatment.
* [http://www.merck.com/mrkshared/mmanual/home.jsp Merck Manual] : [http://www.merck.com/mmpe/sec18/ch248/ch248a.html Uterine fibroids]
* [http://www.emedicine.com/med/topic738.htm Esophageal Leiomyoma]
* [http://www.pathologyatlas.ro/Leiomyoma.html Atlas of Pathology] uterine leimyoma
*humpath [http://www.humpath.com/spip.php?page=article&id_article=4835 #4835] (Pathology images)
* [http://www.gyndr.com/myomectomy.php Laser myomectomy]
* [http://www.ayubmed.edu.pk/JAMC/PAST/16-1/NazliRev.htm Laparoscopic myomectomy] .
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