- Pityriasis lichenoides et varioliformis acuta
Pityriasis lichenoides et varioliformis acuta Classification and external resources ICD-10 L41.0 ICD-9 696.2 eMedicine derm/334
Pityriasis lichenoides et varioliformis acuta (also known as "Acute guttate parapsoriasis," "Acute parapsoriasis," "Acute pityriasis lichenoides," "Mucha-Habermann disease," "Parapsoriasis acuta," "Parapsoriasis lichenoides et varioliformis acuta," and "Parapsoriasis varioliformis":456:736) is a disease of the immune system. It is the more severe version of Pityriasis lichenoides chronica. The disease is characterized by rashes and small lesions on the skin. The disease is most common in females and usually occurs in young adulthood, although it has been seen in every age group and every race. It is possible for the disease to go into remission for short periods of time or forever.
It is commonly misdiagnosed as chickenpox or rosacea. Pleva is also often misidentified as a form of Staph. The most accurate way to diagnose is by biopsy. This disease has not been known to be life threatening. However, there may be mutations of the disease that can cause ulcers on the exterior.
The easiest way to understand this disease is to think of it like this: Everyone has T cells that fight disease; in a person with PLEVA, the T cells get mixed up and decide to form in the skin, causing the lesions. It is unknown why this happens.
The trigger which causes the dysfunctional immune system response, PLEVA, is unknown; bacterial, viral, and environmental causes are suspected, but not conclusively demonstrated. There is another theory that the cause of PLEVA may be linked to lymphs and/or lymph nodes.
Treatment often involves multiple therapies that address the immune system and bacterial, viral, or dermatological causes.
- ^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.
- ^ James, William D.; Berger, Timothy G. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ^ "PLEVA, or Mucha-Habermann disease - MayoClinic.com". Archived from the original on 2007-07-15. http://web.archive.org/web/20070715202757/http://www.mayoclinic.com/health/pleva/AN00709. Retrieved 2007-11-18.
- ^ Tomasini D, Tomasini CF, Cerri A et al. (2004). "Pityriasis lichenoides: a cytotoxic T-cell-mediated skin disorder. Evidence of human parvovirus B19 DNA in nine cases". J. Cutan. Pathol. 31 (8): 531–8. doi:10.1111/j.0303-6987.2004.00186.x. PMID 15268707.
Diseases of the skin and appendages by morphology GrowthsPigmentedDermal and
PurpuraMacularthrombocytopenic purpura · actinic purpuraPapularIndurated
Papulosquamous disorders (L40–L45, 696–697) PsoriasisPustularGeneralized pustular psoriasis (Impetigo herpetiformis) · Acropustulosis/Pustulosis palmaris et plantaris (Pustular bacterid) · Annular pustular psoriasis · Localized pustular psoriasisOther Parapsoriasis Other pityriasis Other lichenoid
configuration: Annular lichen planus · Linear lichen planus
morphology of lesion: Hypertrophic lichen planus · Atrophic lichen planus · Bullous lichen planus · Ulcerative lichen planus · Lichen planus actinicus · Lichen planus pigmentosussite of involvement: Mucosal lichen planus · Lichen planus of the nails · Peno-gingival syndrome · Vulvovaginal gingival syndrome
overlap: Lichen planus–lichen sclerosus overlap syndrome · Lichen planus–lupus erythematosus overlap syndromespecial forms: Hepatitis-associated lichen planus · Lichen planus pemphigoidesOtherLichen nitidus · Lichen striatus · Lichen ruber moniliformis · Gianotti–Crosti syndrome
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