Monokine

Monokine

A monokine is a type of cytokine[1] produced primarily by monocytes and macrophages.

Examples include interleukin 1 and tumor necrosis factor-alpha.

Other monokines include alpha and beta interferon, and colony stimulating factors.[2]

Contents

Functions

Monokines released from macrophages can attract Neutrophils , via the process chemotaxis.

See also

References

  1. ^ MeSH Monokines
  2. ^ Julius M. Cruse; Robert Edwin Lewis (20 April 2009). Illustrated dictionary of immunology. CRC Press. pp. 208–. ISBN 9780849379871. http://books.google.com/books?id=X4X8d2SmQB0C&pg=PA208. Retrieved 24 April 2011. 

External links

v · d · eCell signaling: cytokines
By family
CCL
CCL1 · CCL2/MCP-1 · CCL3/MIP-1α · CCL4/MIP-1β · CCL5/RANTES · CCL6 · CCL7 · CCL8 · CCL9 · CCL11 · CCL12 · CCL13 · CCL14 · CCL15 · CCL16 · CCL17 · CCL18 · CCL19 · CCL20 · CCL21 · CCL22 · CCL23 · CCL24 · CCL25 · CCL26 · CCL27 · CCL28
CXCL
CXCL1/KC · CXCL2 · CXCL3 · CXCL4 · CXCL5 · CXCL6 · CXCL7 · CXCL8/IL8 · CXCL9 · CXCL10 · CXCL11 · CXCL12 · CXCL13 · CXCL14 · CXCL15 · CXCL16 · CXCL17
CX3CL
XCL
TNFA · Lymphotoxin (TNFB/LTA, TNFC/LTB) · TNFSF4 · TNFSF5/CD40LG · TNFSF6 · TNFSF7 · TNFSF8 · TNFSF9 · TNFSF10 · TNFSF11 · TNFSF13B · EDA
Type I
(grouped by
receptor
subunit)
IL2/IL15 · IL4/IL13 · IL7 · IL9 · IL21
IL3 · IL5 · GM-CSF
IL6 like/gp130
IL6  · IL11 · IL27 · IL30 · IL31 (+non IL OSM, LIF, CNTF, CTF1)
IL-12 family/IL12RB1
IL12 · IL23 · IL27 · IL35
Other
IL14 · IL16 · IL32  · IL34
IL-10 family
IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21, IFNB1, IFNK, IFNW1
IL-1 family: IL1A/IL1F1 · IL1B/IL1F2 · 1Ra/IL1F3 · IL1F5 · IL1F6 · IL1F7 · IL1F8 · IL1F9 · IL1F10 · 33/IL1F11  · 18/IL1G
IL-17 family
Other
Hematopoietic (KITLG, Colony-stimulating factor) · SPP1
By function/
cell

proinflammatory cytokine (IL1, TNFA)

Monokine · Lymphokine (Th1 (IFNG and TNFB) · Th2 (IL4, IL5, IL6, IL10, IL13) )
B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)



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Look at other dictionaries:

  • monokine — (mon o kaīn) A generic term for a cytokine produced by mononuclear phagocytes (macrophages or monocytes) …   Dictionary of microbiology

  • monokine — /mon euh kuyn /, n. Immunol. any substance secreted by a monocyte or macrophage and affecting the function of other cells. [MONO + (LYMPHO)KINE] * * * …   Universalium

  • monokine — Cytokines secreted by both monocytes and macrophages. These substances influence the activity of other cells. See cytokine. [monocyte + G. kineo, to set in motion] * * * mono·kine (monґo kīn) a soluble cytokine that mediates immune… …   Medical dictionary

  • monokine — mon•o•kine [[t]ˈmɒn əˌkaɪn[/t]] n. imu a substance that is secreted by monocytes or macrophages in the immune response and that affects the function of other cells • Etymology: mono + (lympho ) kine …   From formal English to slang

  • monokine — Generic name for proteins that are released by monocytes to act on other cells involved in the immune response. A sub class of cytokines …   Glossary of Biotechnology

  • monokine — /mon euh kuyn /, n. Immunol. any substance secreted by a monocyte or macrophage and affecting the function of other cells. [MONO + (LYMPHO)KINE] …   Useful english dictionary

  • CXCL9 — Chemokine (C X C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by gamma interferon (MIG). CXCL9 is a T cell chemoattractant, which is induced by IFN γ. It is closely… …   Wikipedia

  • CXCL9 — (kurz für CXC Ligand 9 oder auch MIG für engl. Monokine induced by Gamma Interferon) bildet mit CXCL10 und CXCL11 eine Gruppe homologer Chemokine (chemotaktisch wirkende Wachstums und Zelldifferenzierungs Regulatoren wie Interferone und… …   Deutsch Wikipedia

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  • Haematopoiesis — Diagram showing the development of different blood cells from haematopoietic stem cell to mature cells Haematopoiesis (from Ancient Greek: αἷμα, blood ; ποιεῖν to make ) (or hematopoiesis in the United States; sometimes also haemopoiesis or… …   Wikipedia

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