IL1F5

IL1F5

Interleukin 1 family, member 5 (delta), also known as IL1F5, is a human gene.cite web | title = Entrez Gene: IL1F5 interleukin 1 family, member 5 (delta)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26525| accessdate = ]

PBB_Summary
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summary_text = The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported.cite web | title = Entrez Gene: IL1F5 interleukin 1 family, member 5 (delta)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26525| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Nicklin MJ, Weith A, Duff GW |title=A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist genes. |journal=Genomics |volume=19 |issue= 2 |pages= 382–4 |year= 1994 |pmid= 8188271 |doi= 10.1006/geno.1994.1076
*cite journal | author=Nothwang HG, Strahm B, Denich D, "et al." |title=Molecular cloning of the interleukin-1 gene cluster: construction of an integrated YAC/PAC contig and a partial transcriptional map in the region of chromosome 2q13. |journal=Genomics |volume=41 |issue= 3 |pages= 370–8 |year= 1997 |pmid= 9169134 |doi= 10.1006/geno.1997.4654
*cite journal | author=Mulero JJ, Pace AM, Nelken ST, "et al." |title=IL1HY1: A novel interleukin-1 receptor antagonist gene. |journal=Biochem. Biophys. Res. Commun. |volume=263 |issue= 3 |pages= 702–6 |year= 1999 |pmid= 10512743 |doi= 10.1006/bbrc.1999.1440
*cite journal | author=Smith DE, Renshaw BR, Ketchem RR, "et al." |title=Four new members expand the interleukin-1 superfamily. |journal=J. Biol. Chem. |volume=275 |issue= 2 |pages= 1169–75 |year= 2000 |pmid= 10625660 |doi=
*cite journal | author=Kumar S, McDonnell PC, Lehr R, "et al." |title=Identification and initial characterization of four novel members of the interleukin-1 family. |journal=J. Biol. Chem. |volume=275 |issue= 14 |pages= 10308–14 |year= 2000 |pmid= 10744718 |doi=
*cite journal | author=Busfield SJ, Comrack CA, Yu G, "et al." |title=Identification and gene organization of three novel members of the IL-1 family on human chromosome 2. |journal=Genomics |volume=66 |issue= 2 |pages= 213–6 |year= 2000 |pmid= 10860666 |doi= 10.1006/geno.2000.6184
*cite journal | author=Mulero JJ, Nelken ST, Ford JE |title=Organization of the human interleukin-1 receptor antagonist gene IL1HY1. |journal=Immunogenetics |volume=51 |issue= 6 |pages= 425–8 |year= 2000 |pmid= 10866108 |doi=
*cite journal | author=Barton JL, Herbst R, Bosisio D, "et al." |title=A tissue specific IL-1 receptor antagonist homolog from the IL-1 cluster lacks IL-1, IL-1ra, IL-18 and IL-18 antagonist activities. |journal=Eur. J. Immunol. |volume=30 |issue= 11 |pages= 3299–308 |year= 2001 |pmid= 11093146 |doi=
*cite journal | author=Pan G, Risser P, Mao W, "et al." |title=IL-1H, an interleukin 1-related protein that binds IL-18 receptor/IL-1Rrp. |journal=Cytokine |volume=13 |issue= 1 |pages= 1–7 |year= 2001 |pmid= 11145836 |doi= 10.1006/cyto.2000.0799
*cite journal | author=Lin H, Ho AS, Haley-Vicente D, "et al." |title=Cloning and characterization of IL-1HY2, a novel interleukin-1 family member. |journal=J. Biol. Chem. |volume=276 |issue= 23 |pages= 20597–602 |year= 2001 |pmid= 11278614 |doi= 10.1074/jbc.M010095200
*cite journal | author=Debets R, Timans JC, Homey B, "et al." |title=Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2. |journal=J. Immunol. |volume=167 |issue= 3 |pages= 1440–6 |year= 2001 |pmid= 11466363 |doi=
*cite journal | author=Sims JE, Nicklin MJ, Bazan JF, "et al." |title=A new nomenclature for IL-1-family genes. |journal=Trends Immunol. |volume=22 |issue= 10 |pages= 536–7 |year= 2001 |pmid= 11574262 |doi=
*cite journal | author=Tazi-Ahnini R, Cox A, McDonagh AJ, "et al." |title=Genetic analysis of the interleukin-1 receptor antagonist and its homologue IL-1L1 in alopecia areata: strong severity association and possible gene interaction. |journal=Eur. J. Immunogenet. |volume=29 |issue= 1 |pages= 25–30 |year= 2002 |pmid= 11841485 |doi=
*cite journal | author=Nicklin MJ, Barton JL, Nguyen M, "et al." |title=A sequence-based map of the nine genes of the human interleukin-1 cluster. |journal=Genomics |volume=79 |issue= 5 |pages= 718–25 |year= 2002 |pmid= 11991722 |doi= 10.1006/geno.2002.6751
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Zee RY, Fernandez-Ortiz A, Macaya C, "et al." |title=IL-1 cluster genes and occurrence of post-percutaneous transluminal coronary angioplasty restenosis: a prospective, angiography-based evaluation. |journal=Atherosclerosis |volume=171 |issue= 2 |pages= 259–64 |year= 2004 |pmid= 14644395 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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