Interleukin 28

Interleukin 28

protein
Name = Interleukin 28A
caption =


width =
HGNCid = 18364
Symbol = IL28A
AltSymbols = , IFNL2
EntrezGene = 282616
OMIM = 607401
RefSeq = NM_172138
UniProt = Q8IZJ0
PDB =
ECnumber =
Chromosome = 19
Arm = q
Band = 13.13
LocusSupplementaryData =protein
Name = Interleukin 28B
caption =


width =
HGNCid = 18365
Symbol = IL28B
AltSymbols = , IFNL3
EntrezGene = 282617
OMIM = 607402
RefSeq = NM_172139
UniProt = Q8IZI9
PDB =
ECnumber =
Chromosome = 19
Arm = q
Band = 13.13
LocusSupplementaryData =

Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses. [D. Kempuraj et al., Interleukin-28 and 29 (IL-28 and IL-29): new cytokines with anti-viral activities. International Journal of Immunopathology and Pharmacology, 2004, Volume 17, pages 103-106.] IL-28A and IL-28B belong to the type III interferon family of cytokines and are highly similar (in amino acid sequence) to IL-29.

IL-28 genes are located near IL-29 on chromosome 19 in humans.

References


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