Interleukin 22

Interleukin 22

protein
Name = Interleukin 22
caption = Crystal structure of human IL-22



width = 250 px
HGNCid = 14900
Symbol = IL22
AltSymbols = , ILTIF, zcyto18, IL-TIF, IL-D110, TIFa, TIFIL-23
EntrezGene = 50616
OMIM = 605330
RefSeq = NM_020525
UniProt = Q9GZX6
PDB = 1M4R
ECnumber =
Chromosome = 12
Arm = q15
Band =
LocusSupplementaryData =

Interleukin-22 (IL-22) is a cytokine with homology to IL-10 that was originally called IL-10-related T cell-derived inducible factor (IL-TIF). Human IL-TIF activates the transcription factors stat-1 and stat-3 in several hepatoma cell lines and up-regulates production of acute phase proteins such as serum amyloid A, 1-antichymotrypsin and haptoglobin in HepG2 human hepatoma cells. [Dumoutier L., Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor. Proc. Natl. Acad. Sci. U.S.A. 2000, Volume 97 pages 10144-10149.] IL-22, signals through the interferon receptor-related proteins CRF2-4 and IL-22R. [Xie "et al.", Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R, Journal of Biological Chemistry, 2000, Volume 275, page 31335-31339.]

References


Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • Interleukin 6 — (interferon, beta 2) PDB rendering based on 1ALU …   Wikipedia

  • Interleukin-2 — Bändermodell nach PDB  …   Deutsch Wikipedia

  • Interleukin-6 — Bändermodell nach PDB  …   Deutsch Wikipedia

  • Interleukin 10 — Bändermodell nach PDB  …   Deutsch Wikipedia

  • Interleukin 6 — Kristallstruktur Interleukin 6 (kurz: IL 6, synonyme ältere Bezeichnungen: Interferon β2 (IFNB2), B Zell stimulierender Faktor, B Zell Differenzierungs Faktor, Leberzell stimulierender Faktor) gehört zu den Interleukinen (bzw. umfassender zu den… …   Deutsch Wikipedia

  • Interleukin 7 — (IL7) is a hematopoietic growth factor secreted by the stromal cells of the red marrow and thymus capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B cell maturation, T… …   Wikipedia

  • Interleukin 11 — (IL 11) is a multifunctional cytokine first isolated in 1990 from bone marrow derived stromal cells. It is a key regulator of multiple events in hemtaopoiesis, most notably the stimulation of megakaryocyte maturation.cite journal | author = Paul… …   Wikipedia

  • Interleukin 2 — (IL 2) is an interleukin, a type of cytokine immune system signaling molecule, that is instrumental in the body s natural response to microbial infection and in discriminating between foreign (non self) and self. IL 2 mediates its effects by… …   Wikipedia

  • Interleukin-1β — Vorhandene Strukturdaten: s. UniProt Masse/Länge …   Deutsch Wikipedia

  • Interleukin 9 — Interleukin 9, also known as IL9, is a cytokine (cell signalling molecule) belonging to the group of interleukins.cite web | title = Entrez Gene: IL9 interleukin 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Interleukin 8 — (IL 8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL 8 in their storage vesicles, the Weibel Palade bodies [Wolff B, Burns AR, Middleton J, Rot A …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”