CXCL15

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Name = chemokine (C-X-C motif) ligand 15
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Symbol = CXCL15
AltSymbols = Lungkine, SCYB15
EntrezGene = 20309
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UniProt = Q9WVL7
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Chemokine (C-X-C motif) ligand 15 (CXCL15) is a small cytokine belonging to the CXC chemokine family that has been described in the mouse. This chemokine is also known under the name "lungkine". CXCL15 is an ELR+ CXC chemokine (it contains the amino acid sequence E-L-R immediately before its CXC motif) that recruits neutrophils during inflammation of the lungs. It is highly abundant in epithelial cells of the lung, [cite journal |author=Rossi D, Hurst S, Xu Y, Wang W, Menon S, Coffman R, Zlotnik A |title=Lungkine, a novel CXC chemokine, specifically expressed by lung bronchoepithelial cells |journal=J Immunol |volume=162 |issue=9 |pages=5490–7 |year=1999 |pmid=10228029] and can also be found in other mucosal organs such as the urogenital and gastrointestinal tracts, and in endocrine organs like the adrenal gland. [cite journal |author=Schmitz J, McCracken V, Dimmitt R, Lorenz R |title=Expression of CXCL15 (Lungkine) in Murine Gastrointestinal, Urogenital, and Endocrine Organs |journal=J Histochem Cytochem |volume= |issue= |pages= |year= |pmid=17242461] The gene for CXCL15 is found on mouse chromosome 5.

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