Ornidazole

Ornidazole
Not to be confused with ronidazole.
Ornidazole
Systematic (IUPAC) name
1-chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat.  ?
Legal status  ?
Routes Oral
Pharmacokinetic data
Metabolism Metabolised via the liver, excreted in the Urine and Feces
Excretion 85% of single oral dose is elimiated with 5 days - Urine (63%) and Feces (22%)
Identifiers
CAS number 16773-42-5 YesY
ATC code G01AF06 J01XD03 P01AB03 QP51AA03
PubChem CID 28061
ChemSpider 26102 YesY
UNII 62XCK0G93T YesY
KEGG D05274 YesY
Chemical data
Formula C7H10ClN3O3 
Mol. mass 219.625
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

Ornidazole is a drug that cures some protozoan infections. It is used by the poultry industry.

It has been investigated for use in Crohn's disease after bowel resection.[1]

References

  1. ^ Rutgeerts P, Van Assche G, Vermeire S, et al. (April 2005). "Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial". Gastroenterology 128 (4): 856–61. doi:10.1053/j.gastro.2005.01.010. PMID 15825069. http://linkinghub.elsevier.com/retrieve/pii/S0016508505000302. 
v · d · eAntibacterials: nucleic acid inhibitors (J01E, J01M)
Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)
2,4-Diaminopyrimidine (Trimethoprim#, Brodimoprim, Tetroxoprim, Iclaprim†)
Sulfonamides
(DHPS inhibitor)
Other/ungrouped
Combinations
Topoisomerase
inhibitors/
quinolones/
(inhibits
DNA replication)
1st g.
2nd g.
3rd g.
4th g.
Vet.
Related (DG)
Anaerobic DNA
inhibitors
Nitro- imidazole derivatives
Metronidazole#  • Tinidazole • Ornidazole
Nitrofuran derivatives
RNA synthesis
#WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III

M: BAC

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)
v · d · eGynecological anti-infectives and antiseptics (G01)
Antibiotics
Arsenic compounds
Quinoline derivatives
Organic acids
Sulfonamides
Sulfatolamide
Imidazole derivatives
Triazole derivatives
Other

M: ♀ FRS

anat/phys/devp

noco/cong/npls, sysi/epon

proc/asst, drug (G1/G2B/G3CD)
v · d · eAntiparasitics – antiprotozoal agents – agents against amoebozoa/amebicide (P01)
Entamoeba
Nitroimidazole derivatives
Metronidazole# • Tinidazole • Ornidazole • Nimorazole • Secnidazole • Azanidazole • Propenidazole
Other
Hydroxyquinoline derivatives

Cl (Chlorquinaldol) • Br (Tilbroquinol, Broxyquinoline) • I (Diiodohydroxyquinoline) • I,Cl (Clioquinol)

related: Chiniofon
Dichloroacetamide derivatives
Diloxanide# • Clefamide • Etofamide • Teclozan
Other/ungrouped
arsenic (Arsthinol, Difetarsone, Glycobiarsol) • phenanthroline (Phanquinone) • aminoacridine (Mepacrine) • quinazoline (Trimetrexate) • thiazole (Tenonitrozole) • sesquiterpene (Fumagillin)
Acanthamoeba
#WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III

M: PRO

ambz, excv, chrm (strc)

ambz, excv, chrm

ambz, excv, chrm


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