Grepafloxacin

drugbox
IUPAC_name = 1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline- 3-carboxylic acid

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CAS_number = 119914-60-2
ATC_prefix = J01
ATC_suffix = MA11
ATC_supplemental =
PubChem = 72474
DrugBank = APRD01003
C = 19 | H = 22 | F = 1 | N = 3 | O = 3
molecular_weight = 359.395 g/mol
bioavailability =
protein_bound = 50%
metabolism =
elimination_half-life =
pregnancy_category =
legal_status =
routes_of_administration =

Grepafloxacin hydrochloride (Raxar, Glaxo Wellcome) is an oral broad-spectrum quinoline antibacterial agent used to treat bacterial infections. Grepafloxacin was withdrawn in the United States owing to its side effect of lengthening the QT interval on the electrocardiogram, leading to cardiac events and sudden death.