- Sulfadiazine
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Sulfadiazine Systematic (IUPAC) name 4-amino-N-pyrimidin- 2-yl-benzenesulfonamide Clinical data AHFS/Drugs.com monograph MedlinePlus a682130 Pregnancy cat. ? Legal status Approved Drug Routes Cream Pharmacokinetic data Bioavailability ? Metabolism ? Half-life ? Excretion ? Identifiers CAS number 68-35-9 ATC code J01EC02 QJ01EQ10 PubChem CID 5215 DrugBank APRD00190 ChemSpider 5026 UNII 0N7609K889 KEGG D00587 ChEMBL CHEMBL439 Chemical data Formula C10H10N4O2S Mol. mass 250.278 g/mol (what is this?) (verify) Sulfadiazine is a sulfonamide antibiotic.
Contents
Uses
It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs).
In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii.
Side effects
Side effects reported for sulfadiazine include: nausea, upset stomach, loss of appetite, and dizziness.
Brand names
Lantrisul; Neotrizine; Sulfa-Triple #2; Sulfadiazine; Sulfaloid; Sulfonamides Duplex; Sulfose; Terfonyl; Triple Sulfa; Triple Sulfas; Triple Sulfoid
See also
External links
- Sulfadiazine (patient information)
Antibacterials: nucleic acid inhibitors (J01E, J01M) Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)Sulfonamides
(DHPS inhibitor)Sulfamethoxazole • Sulfadiazine# • SulfamoxoleOther/ungroupedCombinationsTopoisomerase
inhibitors/
quinolones/
(inhibits
DNA replication)1st g.2nd g.Ciprofloxacin# • Enoxacin‡ • Fleroxacin‡ • Lomefloxacin • Nadifloxacin • Ofloxacin • Norfloxacin • Pefloxacin • Rufloxacin3rd g.4th g.Besifloxacin • Clinafloxacin† • Garenoxacin • Gemifloxacin • Moxifloxacin • Gatifloxacin‡ • Sitafloxacin • Trovafloxacin‡/Alatrofloxacin‡ • PrulifloxacinVet.Related (DG)Anaerobic DNA
inhibitorsNitrofuran derivativesRNA synthesis Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01) Alveo-
latePyrimethamine • SulfadiazineIndividual
agentsOtherDHFR inhibitors
(antifols)Sulfadoxine • sulfamethoxypyrazineCoformulationFansidar# (sulfadoxine/pyrimethamine)OtherCombi-
nationsFixed-dose (coformulated) ACTsartemether-lumefantrine#
artesunate-amodiaquine (ASAQ)
artesunate-mefloquine (ASMQ)
dihydroartemisinin-piperaquine
artesunate-pyronaridineOther combinations
(not co-formulated)artesunate/SP • artesunate/mefloquine •
quinine/tetracycline • quinine/doxycycline • quinine/clindamycinHetero-
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