Rifapentine

Rifapentine

drugbox
IUPAC_name = 3{ [(4-cyclopentyl-1-piperazinyl)imino] methyl}rifamycin


width = 250
CAS_number = 61379-65-5
ATC_prefix = J04
ATC_suffix = AB05
ATC_supplemental =
PubChem = 5462354
DrugBank = APRD01217
C=47 | H=64 | N=4 | O=12
molecular_weight = 877.031 g/mol
bioavailability = increases when administered with food
protein_bound =
metabolism =
elimination_half-life =
pregnancy_category =
legal_status =
routes_of_administration =

Rifapentine (INN, marketed under the brand name Priftin by Sanofi-Aventis) is an antibiotic drug used in the treatment of tuberculosis.

History

Rifapentine was first synthesized in 1965 by the same company that produced rifampin. The drug was approved by the Food and Drug Administration (FDA) in June 1998.

External links

*cite journal |author=Rosenthal IM, Zhang M, Williams KN, "et al" |title=Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model |journal=PLoS Medicine |volume=4 |issue=12 |pages=e344 |year=2007 |month=December |pmid=18092886 |pmc=2140085 |doi=10.1371/journal.pmed.0040344


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