Sulfadimethoxine

Sulfadimethoxine: Sulfadimethoxine

Systematic (IUPAC) name

4-amino-N-(2,6-dimethoxypyrimidin-4-yl)
benzenesulfonamide

Clinical data

AHFS/Drugs.com FDA Professional Drug Information

Pregnancy cat. ?

Legal status ?

Identifiers

CAS number 122-11-2^Y

ATC code J01ED02 QJ01EQ09 QP51AG02

PubChem CID 5323

DrugBank DB06150

ChemSpider 5132^Y

UNII 30CPC5LDEX^Y

KEGG D01142^Y

ChEBI CHEBI:32161^N

ChEMBL CHEMBL62193^Y

Chemical data

Formula C₁₂H₁₄N₄O₄S

Mol. mass 310.33 g/mol

SMILES eMolecules & PubChem

InChI

InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)^Y
Key:ZZORFUFYDOWNEF-UHFFFAOYSA-N^Y

N(what is this?) (verify)

Sulfadimethoxine (trade name Di-Methox, Albon) is a sulfonamide antibiotic. Albon is produced by Pfizer Animal Health and is available as a oral suspension, tablet or bolus. It is used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.[1] It is most frequently used in veterinary medicine. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic acid. It is also commonly used for the treatment of coccidiosis in many species.[2]

Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully used there for more than 35 years.^[1] It is widely available in Russia as an over-the-counter drug manufactured by a number of Russian pharmaceutical companies.

Contents

1 Side Effects

2 Uses

3 Actions

4 Notes

5 External links

Side Effects

Some side effects include:

Redness of the eye[3]

Discharge form the eye

Other symptoms related to the eye

Bleeding

Vomiting and diarrhea

Increased thirst is common[4]

insessant itch

Animals should be kept well hydrated to prevent the formation of sulfa crystals in the animal's urine.[5]

Uses

It can be used for [6]:

metritis

tonsillitis

pharyngitis

pneumonia

pyometra

anal gland infections

dermatitis

wounds and abscesses

enteritis

salmonellosis

enteritis associated with coccidiosis in dogs

Actions

It has been shown to be effective against streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.

Notes

^ ru:Сульфадиметоксин

External links

Albon Oral Suspension product overview

Albon Tablets product overview

Albon Bolus product overview

Coccidia Treatment

Sulfadimethoxine

v · d · eAntibacterials: nucleic acid inhibitors (J01E, J01M)

Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)

DHFR inhibitor

2,4-Diaminopyrimidine (Trimethoprim^#, Brodimoprim, Tetroxoprim, Iclaprim^†)

Sulfonamides
(DHPS inhibitor)

Short-
acting

Sulfaisodimidine • Sulfamethizole • Sulfadimidine • Sulfapyridine • Sulfafurazole • Sulfanilamide (Prontosil) • Sulfathiazole • Sulfathiourea

Intermediate-
acting

Sulfamethoxazole • Sulfadiazine^# • Sulfamoxole

Long-
acting

Sulfadimethoxine • Sulfalene • Sulfametomidine • Sulfametoxydiazine • Sulfamethoxypyridazine • Sulfaperin • Sulfamerazine • Sulfaphenazole • Sulfamazone

Other/ungrouped

sulfanilamide (Sulfacetamide, Sulfametrole)

Combinations

Trimethoprim/sulfamethoxazole^#

Topoisomerase
inhibitors/
quinolones/
(inhibits
DNA replication)

1st g.

Cinoxacin^‡ • Flumequine • Nalidixic acid • Oxolinic acid • Pipemidic acid • Piromidic acid • Rosoxacin

Fluoro-
quinolones

2nd g.

Ciprofloxacin^# • Enoxacin^‡ • Fleroxacin^‡ • Lomefloxacin • Nadifloxacin • Ofloxacin • Norfloxacin • Pefloxacin • Rufloxacin

3rd g.

Balofloxacin • Grepafloxacin^‡ • Levofloxacin • Pazufloxacin • Sparfloxacin^‡ • Temafloxacin^‡ • Tosufloxacin

4th g.

Besifloxacin • Clinafloxacin^† • Garenoxacin • Gemifloxacin • Moxifloxacin • Gatifloxacin^‡ • Sitafloxacin • Trovafloxacin^‡/Alatrofloxacin^‡ • Prulifloxacin

Vet.

Danofloxacin • Difloxacin • Enrofloxacin • Ibafloxacin • Marbofloxacin • Orbifloxacin • Pradofloxacin • Sarafloxacin

Related (DG)

Aminocoumarins: Novobiocin

Anaerobic DNA
inhibitors

Nitro- imidazole derivatives

Metronidazole^# • Tinidazole • Ornidazole

Nitrofuran derivatives

Nitrofurantoin^# • Furazolidone^‡ • Nifurtoinol

RNA synthesis

Rifamycins/
RNA polymerase

Rifampicin • Rifabutin • Rifapentine • Rifaximin

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: BAC

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)

Categories:
Sulfonamide antibiotics
Pyrimidines
Phenol ethers

Sulfadimethoxine

Systematic (IUPAC) name
4-amino-N-(2,6-dimethoxypyrimidin-4-yl) benzenesulfonamide
Clinical data
AHFS/Drugs.com	FDA Professional Drug Information
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	122-11-2^Y
ATC code	J01ED02 QJ01EQ09 QP51AG02
PubChem	CID 5323
DrugBank	DB06150
ChemSpider	5132^Y
UNII	30CPC5LDEX^Y
KEGG	D01142^Y
ChEBI	CHEBI:32161^N
ChEMBL	CHEMBL62193^Y
Chemical data
Formula	C₁₂H₁₄N₄O₄S
Mol. mass	310.33 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)^Y Key:ZZORFUFYDOWNEF-UHFFFAOYSA-N^Y
N(what is this?) (verify)

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

sulfadimethoxine — noun A sulfonamide antibacterial derivative of sulfadiazine … Wiktionary
sulfadimethoxine — A long acting sulfonamide that is rapidly absorbed after oral administration and is slowly excreted by the kidney; it accumulates in the tissue and requires lower doses to attain effective tissue concentrations than do the other sulfonamides. * * … Medical dictionary
SDMD — sulfadimethoxine … Medical dictionary
SDMD — • sulfadimethoxine … Dictionary of medical acronyms & abbreviations
СУЛЬФАДИМЕТОКСИН — Действующее вещество ›› Сульфадиметоксин* (Sulfadimethoxine*) Латинское название Sulfadimethoxine АТХ: ›› J01ED01 Сульфадиметоксин Фармакологическая группа: Сульфаниламиды Состав и форма выпуска 1 таблетка содержит сульфадиметоксина 0,5 г; в… … Словарь медицинских препаратов
Ciprofloxacin — Not to be confused with Cipralex, a brand name of the antidepressant escitalopram. Cipro redirects here. For the Rome Metro station, see Cipro (Rome Metro). Ciprofloxacin … Wikipedia
Trimethoprim — Systematic (IUPAC) name … Wikipedia
Metronidazole — Systematic (IUPAC) name 2 (2 methyl 5 nitro 1H … Wikipedia
Sulfonamide (medicine) — There are several sulfonamide based groups of drugs. The original antibacterial sulfonamides (sometimes called simply sulfa drugs) are synthetic antimicrobial agents that contain the sulfonamide group. Some sulfonamides are also devoid of… … Wikipedia
Levofloxacin — Systematic (IUPAC) name (S) 7 fluoro 6 (4 methylpiperazin 1 yl) 10 oxo 4 thia 1 azatricyclo[7.3.1.05,13] trideca 5(13),6,8,11 tetraene 11 carboxylic acid … Wikipedia

Academic Dictionaries and Encyclopedias

Sulfadimethoxine

Contents

Side Effects

Uses

Actions

Notes

External links

Look at other dictionaries:

Share the article and excerpts

Academic Dictionaries and Encyclopedias

Wikipedia

Sulfadimethoxine

Contents

Side Effects

Uses

Actions

Notes

External links

Look at other dictionaries:

Share the article and excerpts

Direct link