Brodimoprim

Drugbox
IUPAC_name = 5- [(4-bromo-3,5-dimethoxyphenyl)methyl]
pyrimidine-2,4-diamine

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CAS_number =
ATC_prefix = J01
ATC_suffix = EA02
PubChem = 68760
DrugBank =
C=13|H=15|Br=1|N=4|O=2
molecular_weight = 339.188 g/mol
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Brodimoprim is a structural derivative of trimethoprim. In brodimoprim, the 4-methoxy group of trimethoprim is replaced with a bromine atom.

As trimethoprim, brodimoprim is a selective inhibitor of bacterial dihydrofolate reductase. [cite journal |author=Thomson CJ |title=Trimethoprim and brodimoprim resistance of gram-positive and gram-negative bacteria |journal=J Chemother |volume=5 |issue=6 |pages=45864 |year=1993 |pmid=8195838 |doi=]

References