Clinafloxacin

Clinafloxacin
Clinafloxacin
Systematic (IUPAC) name
7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 105956-99-8
ATC code None
PubChem CID 60062
ChemSpider 54184
UNII 8N86XTF9QD YesY
KEGG D02539
ChEMBL CHEMBL278255
Chemical data
Formula C17H17ClFN3O3 
Mol. mass 365.786 g/mol
SMILES eMolecules & PubChem

Clinafloxacin (INN) is a quinolone antibiotic. Its use is associated with phototoxicity and hypoglycaemia.[1]

See also

  • Fluoroquinolone toxicity
  • Fluoroquinolone

References

  1. ^ Rubinstein, E. (2001). "History of quinolones and their side effects.". Chemotherapy 47 Suppl 3: 3–8; discussion 44–8. doi:10.1159/000057838. PMID 11549783. 
v · d · eAntibacterials: nucleic acid inhibitors (J01E, J01M)
Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)
2,4-Diaminopyrimidine (Trimethoprim#, Brodimoprim, Tetroxoprim, Iclaprim†)
Sulfonamides
(DHPS inhibitor)
Other/ungrouped
Combinations
Topoisomerase
inhibitors/
quinolones/
(inhibits
DNA replication)
1st g.
2nd g.
3rd g.
4th g.
Besifloxacin • Clinafloxacin† • Garenoxacin • Gemifloxacin • Moxifloxacin • Gatifloxacin‡ • Sitafloxacin • Trovafloxacin‡/Alatrofloxacin‡ • Prulifloxacin
Vet.
Related (DG)
Anaerobic DNA
inhibitors
Nitro- imidazole derivatives
Nitrofuran derivatives
RNA synthesis
#WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III

M: BAC

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)


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