Tioconazole

Tioconazole
Tioconazole
Systematic (IUPAC) name
(RS)-1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
Clinical data
Trade names Vagistat-1
AHFS/Drugs.com monograph
Pregnancy cat.  ?
Legal status  ?
Routes Topical
Identifiers
CAS number 65899-73-2 YesY
ATC code D01AC07 G01AF08
PubChem CID 5482
DrugBank APRD01262
ChemSpider 5282 N
UNII S57Y5X1117 N
KEGG D00890 YesY
ChEMBL CHEMBL1200438 N
Synonyms Thioconazole
Chemical data
Formula C16H13Cl3N2OS 
Mol. mass 387.711 g/mol
 N(what is this?)  (verify)

Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names. Tioconazole ointments serve to treat women's vaginal yeast infections.[1] They are available in one day doses, as opposed to the 7-day treatments more common in use in the past.

Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".

Side effects

Side effects (for the women's formulas) may include temporary burning/irritation of the vaginal area, moderate drowsiness, headache similar to a sinus headache, hives, and upper respiratory infection.[citation needed] These side effects may be only temporary, and do not normally interfere with the patient's comfort enough to outweigh the end result.

References

  1. ^ Tioconazole, Mayo Clinic
v · d · eAntifungals (D01 and J02)
Wall/
membrane
Ergosterol
inhibitors
topical: Thiabendazole
topical: (Natamycin, Nystatin#)
systemic: (Amphotericin B#)
Intracellular
Pyrimidine analogues/
Thymidylate synthase inhibitors
Others

Bromochlorosalicylanilide • Methylrosaniline • Tribromometacresol • Undecylenic acid • Polynoxylin • Chlorophetanol • Chlorphenesin • Ticlatone • Sulbentine • Ethyl hydroxybenzoate • Haloprogin • Salicylic acid • Selenium sulfide# • Ciclopirox • Amorolfine • Dimazole • Tolnaftate • Tolciclate • Sodium thiosulfate# • Whitfield's ointment# • Potassium iodide#

Tea tree oil • citronella oil • lemon grass • orange oil • patchouli • lemon myrtle

PCP: Pentamidine • Dapsone • Atovaquone

M: MYC

fung, clas

fung

drug (fung)
v · d · eGynecological anti-infectives and antiseptics (G01)
Antibiotics
Arsenic compounds
Quinoline derivatives
Organic acids
Sulfonamides
Sulfatolamide
Imidazole derivatives
Triazole derivatives
Other

M: ♀ FRS

anat/phys/devp

noco/cong/npls, sysi/epon

proc/asst, drug (G1/G2B/G3CD)


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