Haloprogin

"Polik" redirects here. For other uses, see Polik (disambiguation).

Haloprogin

Systematic (IUPAC) name
1,2,4-trichloro-5-[(3-iodoprop-2-yn-1-yl)oxy]benzene
Clinical data
Pregnancy cat.	?
Legal status	Not available in U.S.
Routes	Topical
Identifiers
CAS number	777-11-7
ATC code	D01AE11
PubChem	CID 3561
DrugBank	APRD01011
ChemSpider	3440 Y
UNII	AIU7053OWL Y
KEGG	D00339 Y
ChEMBL	CHEMBL1289 Y
Chemical data
Formula	C9H4Cl3IO
Mol. mass	361.39 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C9H4Cl3IO/c10-6-4-8(12)9(5-7(6)11)14-3-1-2-13/h4-5H,3H2 Y Key:CTETYYAZBPJBHE-UHFFFAOYSA-N Y
Physical data
Melt. point	113.5 °C (236 °F)
Solubility in water	insoluble mg/mL (20 °C)
Y(what is this?)  (verify)

Haloprogin is an antifungal drug used to treat athlete's foot and other fungal infections. It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.

Action

Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over the counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.^[1]

Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.^[2]

References

1. ^ "Haloprogin". Drugs@FDA. Food and Drug Administration. http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Overview&DrugName=HALOTEX. Retrieved 2007-02-17. 
2. ^ "Haloprogin". DrugBank. University of Alberta. Nov 06, 2006. http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-bin/getCard.cgi?CARD=APRD01011.txt. Retrieved 2007-02-17. 

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This dermatologic drug article is a stub. You can help Wikipedia by expanding it.v · Categories: Antifungals Organoiodides Organochlorides Alkynes Antiinfective agent stubs Dermatologic drug stubs Wikimedia Foundation. 2010. Игры ⚽ Нужно решить контрольную? Ferret (disambiguation) Gray H. Miller Look at other dictionaries: haloprogin — noun An antifungal drug, no longer widely used because of its many side effects …   Wiktionary haloprogin — hal·o·pro·gin (hal″o proґjin) a synthetic topical antifungal used in the treatment of various forms of tinea …   Medical dictionary Antifungal drug — An antifungal drug is medication used to treat fungal infections such as athlete s foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcal meningitis, and others. Such drugs are usually obtained by a doctor s… …   Wikipedia Salicylic acid — Salicylic acid …   Wikipedia Pentamidine — Systematic (IUPAC) name 4,4 [pentane 1,5 diylbis(ox …   Wikipedia Itraconazole — Systematic (IUPAC) name (2R,4S) rel 1 (butan 2 yl) 4 {4 [4 (4 {[(2R,4S) 2 (2,4 dichlorophenyl) 2 (1H 1,2,4 triazol 1 ylmethyl) 1,3 dioxolan 4 yl]methoxy}phenyl)piperazin 1 yl]phenyl} 4,5 dihydro 1H 1,2,4 …   Wikipedia Tea tree oil — (Melaleuca Oil) Tea tree oil, or melaleuca oil, is a pale yellow colour to nearly clear essential oil with a fresh camphoraceous odor.[1] It is taken from the leaves of the …   Wikipedia Nystatin — Systematic (IUPAC) name (1S,3R,4R,7R,9R,11R,15S,16R,17R,18S,19E,21E, 25E,27E,29E,31E,33R,35S,36R,37S) 33 [(3 amino 3 …   Wikipedia Amphotericin B — Systematic (IUPAC) name (1R,3S,5R,6R,9 …   Wikipedia Ketoconazole — Systematic (IUPAC) name 1 [4 (4 {[(2R,4 …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”