Povidone-iodine

Povidone-iodine

drugbox
IUPAC_name = 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine.


CAS_number = 25655-41-8
ATC_prefix = S01
ATC_suffix = AX18
ATC_supplemental = ATC|D08|AG02 ATC|D09|AA09 ATC|D11|AC06 ATC|G01|AX11 ATC|R02|AA15
PubChem =
DrugBank =
chemical_formula = (C6H9NO)n·xI
molecular_weight =
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routes_of_administration = topical, when formulated

Povidone-iodine (PVPI) is a water-soluble complex of iodine with polyvinylpyrrolidone (PVP), with from 9.0% to 12.0% available iodine, calculated on a dry basis [ [http://www.usp.org/USPNF/faq.html#III_Q3 United States Pharmacopeia] ] .

PVPI can be further formulated into topical antiseptic products as a solution (with surfactants and/or alcohol), aerosol or ointment at concentrations from 7.5% to 10%. These products are sold over-the-counter (OTC) and used in hospitals for cleansing and disinfecting the skin, preparing the skin preoperatively and treating infections susceptible to iodine.

It works through disruption of pathogen cell walls.

Notes and references

ee also

* Tincture of iodine
* Lugol's iodine
* Betadine
* Iodophor


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Look at other dictionaries:

  • povidone-iodine — SYN: povidone iodine. * * * povidone iodine n a solution of polyvinylpyrrolidone and iodine used as an antibacterial agent in topical application (as in preoperative prepping or a surgical scrub) see BETADINE * * * see povidone iodine at P …   Medical dictionary

  • povidone iodine — (Pharmacology) yellowish brown compound made from iodine and the polymer povidone (used as a topical antiseptic) …   English contemporary dictionary

  • povidone-iodine — /poh vi dohn uy euh duyn , din/, n. Pharm. a complex of iodine and polyvinylpyrrolidone that has broad spectrum antimicrobial activity: used as an antiseptic. [PO(LY)VI(NYLPYRROLI)DONE] * * * …   Universalium

  • povidone-iodine — /poh vi dohn uy euh duyn , din/, n. Pharm. a complex of iodine and polyvinylpyrrolidone that has broad spectrum antimicrobial activity: used as an antiseptic. [PO(LY)VI(NYLPYRROLI)DONE] …   Useful english dictionary

  • Iodine — An essential element in the diet used by the thyroid gland to make thyroid hormones. The two most important thyroid hormones are thyroxine (T4) and triiodothyronine (T3). Thyroxine (T4) has four iodine molecules attached to its structure, while… …   Medical dictionary

  • Povidone — Strukturformel Allgemeines Name Polyvinylpyrrolidon Andere Namen 1 Ethenyl 2 pyrrolidon …   Deutsch Wikipedia

  • iodine — n. an element required in small amounts for healthy growth and development. An adult body contains about 30 mg of iodine, mostly concentrated in the thyroid gland: this gland requires iodine to synthesize thyroid hormones. A deficiency of iodine… …   The new mediacal dictionary

  • povidone — A synthetic polymer consisting mainly of linear 1 vinyl 2 pyrrolidone groups, with mean molecular weights ranging from 10,000 to 70,000; used as a dispersing and suspending agent; p. with molecular weight between 20,000 and 40,000 has been used… …   Medical dictionary

  • Tincture of iodine — is a disinfectant, usually 8% elemental iodine in ethanol. Overview Tincture of iodine is often found in emergency survival kits, used both to disinfect wounds and to sanitize surface water for drinkingcite… …   Wikipedia

  • polyvinylpyrrolidone-iodine complex — SYN: povidone iodine …   Medical dictionary

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