Brain implant

Brain implant

Brain implants, often referred to as neural implants, are technological devices that connect directly to a biological subject's brain - usually placed on the surface of the brain, or attached to the brain's cortex. A common purpose of modern brain implants and the focus of much current research is establishing a biomedical prosthesis circumventing areas in the brain that have become dysfunctional after a stroke or other head injuries. This includes sensory substitution, e.g. in vision. Other brain implants are used in animal experiments simply to record brain activity for scientific reasons. Some brain implants involve creating interfaces between neural systems and computer chips. This work is part of a wider research field called brain-computer interfaces. (Brain-computer interface research also includes technology such as EEG arrays that allow interface between mind and machine but do not require direct implantation of a device.)

Neural-implants such as deep brain stimulation and Vagus nerve stimulation are increasingly becoming routine for patients with Parkinson's disease and clinical depression respectively, proving themselves as a boon for people with diseases which were previously regarded as incurable.



Brain implants electrically stimulate, block[1] or record (or both record and stimulate simultaneously[2]) signals from single neurons or groups of neurons (biological neural networks) in the brain. The blocking technique is called intra-abdominal vagal blocking.[1] This can only be done where the functional associations of these neurons are approximately known. Because of the complexity of neural processing and the lack of access to action potential related signals using neuroimaging techniques, the application of brain implants has been seriously limited until recent advances in neurophysiology and computer processing power.


Research in sensory substitution has made slow progress in recent years. Especially in vision, due to the knowledge of the working of the visual system, eye implants (often involving some brain implants or monitoring) have been applied with demonstrated success. For hearing, cochlear implants are used to stimulate the auditory nerve directly. The vestibulocochlear nerve is part of the peripheral nervous system, but the interface is similar to that of true brain implants.

Multiple projects have demonstrated success at recording from the brains of animals for long periods of time. As early as 1976, researchers at the NIH led by Edward Schmidt made action potential recordings of signals from Rhesus monkey motor cortexes using immovable "hatpin" electrodes,[3] including recording from single neurons for over 30 days, and consistent recordings for greater than three years from the best electrodes.

The "hatpin" electrodes were made of pure iridium and insulated with Parylene-c, materials that are currently used in the Cyberkinetics implementation of the Utah array.[4] These same electrodes, or derivations thereof using the same biocompatible electrode materials, are currently used in visual prosthetics laboratories,[5] laboratories studying the neural basis of learning,[6] and motor prosthetics approaches other than the Cyberkinetics probes.[7]

Schematic of the "Utah" Electrode Array

A competing series of electrodes and projects is sold by Plexon including Plextrode Series of Electrodes. These are variously the "Michigan Probes",[8] the microwire arrays first used at MIT,[9] and the FMAs from MicroProbe that emerged from the visual prosthetic project collaboration between Phil Troyk, David Bradley, and Martin Bak.[10]

Other laboratory groups produce their own implants to provide unique capabilities not available from the commercial products.[11][12][13][14]

Breakthroughs include studies of the process of functional brain re-wiring throughout the learning of a sensory discrimination,[15] control of physical devices by rat brains,[16] monkeys over robotic arms,[17] remote control of mechanical devices by monkeys and humans,[18] remote control over the movements of roaches,[19] electronic-based neuron transistors for leeches,[20] the first reported use of the Utah Array in a human for bidirectional signalling.[21] Currently a number of groups are conducting preliminary motor prosthetic implants in humans. These studies are presently limited to several months by the longevity of the implants.


Brain pacemakers have been in use since 1997 to ease the symptoms of such diseases as epilepsy, Parkinson's Disease, dystonia and recently depression.

Current brain implants are made from a variety of materials such as tungsten, silicon, platinum-iridium, or even stainless steel. Future brain implants may make use of more exotic materials such as nanoscale carbon fibers (nanotubes), and polycarbonate urethane.

Historical research on brain implants

In 1870, Eduard Hitzig and Gustav Fritsch demonstrated that electrical stimulation of the brains of dogs could produce movements. Robert Bartholow showed the same to be true for humans in 1874. By the start of the 20th century Fedor Krause began to systematically map human brain areas, using patients that had undergone brain surgery.

Prominent research was conducted in the 1950s. Robert G. Heath experimented with aggressive mental patients, aiming to influence his subjects' moods through electrical stimulation.

Yale University physiologist Jose Delgado demonstrated limited control of animal and human subjects' behaviours using electronic stimulation. He invented the stimoceiver or transdermal stimulator a device implanted in the brain to transmit electrical impulses that modify basic behaviours such as aggression or sensations of pleasure.

Delgado was later to write a popular book on mind control, called "Physical Control of the Mind", where he stated: "the feasibility of remote control of activities in several species of animals has been demonstrated [...] The ultimate objective of this research is to provide an understanding of the mechanisms involved in the directional control of animals and to provide practical systems suitable for human application."

In the 1950s, the CIA also funded research into mind control techniques, through programs such as MKULTRA. Perhaps because he received funding for some research through the US Office of Naval Research, it has been suggested (but not proven) that Delgado also received backing through the CIA. He denied this claim in a 2005 article in Scientific American describing it only as a speculation by conspiracy-theorists. He stated that his research was only progressively scientifically-motivated to understand how the brain works.

Ethical considerations

Who are good candidates to receive neural implants? What are the good uses of neural implants, and what are the bad uses? Whilst deep brain stimulation is increasingly becoming routine for patients with Parkinson's disease, there may be some behavioural side effects. Reports in the literature describe the possibility of apathy, hallucinations, compulsive gambling, hypersexuality, cognitive dysfunction, and depression. However, these may be temporary and related to correct placement and calibration of the stimulator and so are potentially reversible.[22]

Some transhumanists, such as Raymond Kurzweil and Kevin Warwick, see brain implants as part of a next step for humans in progress and evolution, where as others, especially bioconservatives, view them as unnatural, with humankind losing essential human qualities. It raises controversy similar to other forms of human enhancement. For instance, it is argued that implants would technically change people into cybernetic organisms (cyborgs). Some people fear implants may be used for mind control, e.g. to change human perception of reality.

Brain implants in fiction and philosophy

Brain implants are now part of modern culture but there were early philosophical references of relevance as far back as René Descartes.

In his 1638 Discourse on the Method, a study on proving self existence, Descartes wrote that a person would not know if an evil demon had trapped his mind in a black box and was controlling all inputs and outputs. Philosopher Hilary Putnam provided a modern parallel of Descartes argument in his 1989 discussion of a brain in a vat, where he argues that brains which were directly fed with an input from a computer would not know the deception from reality.

Popular science fiction discussing brain implants and mind control became widespread in the 20th century, often with a dystopian outlook. Literature in the 1970s delved into the topic, including The Terminal Man by Michael Crichton, where a man suffering from brain damage receives an experimental surgical brain implant designed to prevent seizures, which he abuses by triggering for pleasure.

Fear that the technology will be misused by the government and military is an early theme. In the 1981 BBC serial The Nightmare Man the pilot of a high-tech mini submarine is linked to his craft via a brain implant but becomes a savage killer after ripping out the implant.

Perhaps the most influential novel exploring the world of brain implants was William Gibson's 1984 novel Neuromancer. This was the first novel in a genre that came to be known as "cyberpunk". It follows a computer hacker through a world where mercenaries are augmented with brain implants to enhance strength, vision, memory, etc. Gibson coins the term "matrix" and introduces the concept of "jacking in" with head electrodes or direct implants. He also explores possible entertainment applications of brain implants such as the "simstim" (simulated stimulation) which is a device used to record and playback experiences.

Gibson's work led to an explosion in popular culture references to brain implants. Its influences are felt, for example, in the 1989 roleplaying game Shadowrun, which borrowed his term "datajack" to describe a brain-computer interface. The implants in Gibson's novels and short stories formed the template for the 1995 film Johnny Mnemonic and later, The Matrix Trilogy.

The Gap Cycle (The Gap into): In Stephen R. Donaldson's series of novels, the use (and misuse) of "zone implant" technology is key to several plotlines.

Pulp fiction with implants or brain implants include the novel series Typers, film Spider-Man 2, the TV series Earth: Final Conflict, and numerous computer/video games.

Ghost in the Shell anime and manga franchise: Cyberbrain neural augmentation technology is the focus. Implants of powerful computers provide vastly increased memory capacity, total recall, as well as the ability to view his or her own memories on an external viewing device. Users can also initiate a telepathic conversation with other cyberbrain users, the downsides being cyberbrain hacking, malicious memory alteration, and the deliberate distortion of subjective reality and experience.

In the video games PlanetSide and Chrome, players can use implants to improve their aim, run faster, and see better, along with other enhancements.


Brainstorm (1983): The military tries to take control over a new technology that can record and transfer thoughts, feelings, and sensations.

The Manchurian Candidate (2004): For a means of mind control, the presidential hopeful Raymond Shaw unknowingly has a chip implanted in his head by Manchurian Global, a fictional geopolitical organization aimed at making parts of the government sleeper cells, or puppets for their monetary advancement.

South Park: Bigger, Longer & Uncut: The "V-chip" implant is a satirical implant for foul-mouthed children, and serves a related purpose to the true V-chip (it delivers an electric shock to the child whenever they swear).

The extreme box office success of the Matrix films, combined with earlier science fiction references, have made brain implants ubiquitous in popular literature.


Blake's 7: A character has a brain implant which is supposed to prevent future aggression after being convicted of killing an officer from the oppressive Federation.

Dark Angel: The notorious Red Series use neuro-implants pushed into their brain stem at the base of their skull to amp them up and hyper-adrenalize them and make them almost unstoppable. Unfortunately the effects of the implant burn out their system between six months to a year and kill them.

The X-Files (episode?): FBI Agent Dana Scully discovers an implant set under the skin at the back of her neck which can read her every thought and change memory through electrical signals that alter the brain chemistry.

Star Trek franchise: Members of the Borg collective are equipped with brain implants which connect them to the Borg collective consciousness.

See also


  1. ^ a b "Access". Medscape. Retrieved 2011-08-14. 
  2. ^ June 21, 2007 Patrick Mahoney (2007-06-21). "Wireless is getting under our skin". Machine Design. Retrieved 2011-08-14. 
  3. ^ Schmidt, E.M.; Bak, M.J.; McIntosh, J.S. (1976). "Long-term chronic recording from cortical neurons". Experimental Neurology 52 (3): 496–506. doi:10.1016/0014-4886(76)90220-X. PMID 821770. 
  4. ^[dead link] Cyberkinetics array
  5. ^ Troyk, Philip; Bak, Martin; Berg, Joshua; Bradley, David; Cogan, Stuart; Erickson, Robert; Kufta, Conrad; McCreery, Douglas et al. (2003). "A Model for Intracortical Visual Prosthesis Research". Artificial Organs 27 (11): 1005–15. doi:10.1046/j.1525-1594.2003.07308.x. PMID 14616519. 
  6. ^ Blake, David T.; Heiser, Marc A.; Caywood, Matthew; Merzenich, Michael M. (2006). "Experience-Dependent Adult Cortical Plasticity Requires Cognitive Association between Sensation and Reward". Neuron 52 (2): 371–81. doi:10.1016/j.neuron.2006.08.009. PMC 2826987. PMID 17046698. 
  7. ^ "Neuroscientists Demonstrate New Way to Control Prosthetic Device with Brain Signals" (Press release). Caltech. July 8, 2004. Retrieved February 26, 2011. 
  8. ^ [1][dead link]
  9. ^ Chorover, S; Deluca, A (1972). "A sweet new multiple electrode for chronic single unit recording in moving animals". Physiology & Behavior 9 (4): 671–4. doi:10.1016/0031-9384(72)90030-3. 
  10. ^ Troyk, P.R.; Bradley, D.; Bak, M.; Cogan, S.; Erickson, R.; Hu, Z.; Kufta, C.; McCreery, D. et al. (2005). Intracortical Visual Prosthesis Research - Approach and Progress. pp. 7376–9. doi:10.1109/IEMBS.2005.1616216. 
  11. ^ "Laboratory for Integrative Neural Systems | RIKEN". Retrieved 2011-08-14. 
  12. ^ "Blake Laboratory: Neural basis of behavior". 2007-08-16. Retrieved 2011-08-14. 
  13. ^ "Robert H. Wurtz, Ph.D. [NEI Laboratories]". Retrieved 2011-08-14. 
  14. ^ "Brain Research Institute". Retrieved 2011-08-14. 
  15. ^ "Making the connection between a sound and a reward changes brain and behavior". 2006-10-19. Retrieved 2008-04-25. 
  16. ^ Chapin, John K.. "Robot arm controlled using command signals recorded directly from brain neurons". SUNY Downstate Medical Center. Retrieved 2008-04-25. 
  17. ^ Graham-Rowe, Duncan (2003-10-13). "Monkey's brain signals control 'third arm'". New Scientist. Retrieved 2008-04-25. 
  18. ^ Mishra, Raja (2004-10-09). "Implant could free power of thought for paralyzed". Boston Globe. Retrieved 2008-04-25. 
  19. ^ Talmadoe, Eric (2001-07). "Japan's latest innovation: a remote-control roach". Associated Press. Retrieved 2008-04-25. 
  20. ^ Gross, Michael (2004-09). "Plugging brains into computers". Chemistry World (Royal Society of Chemistry). Retrieved 2008-04-25. 
  21. ^ Warwick, K.; Gasson, M; Hutt, B; Goodhew, I; Kyberd, P; Andrews, B; Teddy, P; Shad, A (2003). "The Application of Implant Technology for Cybernetic Systems". Archives of Neurology 60 (10): 1369–73. doi:10.1001/archneur.60.10.1369. PMID 14568806. 
  22. ^ Burn, D. J.; Tröster, AI (2004). "Neuropsychiatric Complications of Medical and Surgical Therapies for Parkinson's Disease". Journal of Geriatric Psychiatry and Neurology 17 (3): 172–80. doi:10.1177/0891988704267466. PMID 15312281. 

External links

Further reading

  • Berger, Theodore W.; Glanzman, Dennis L., eds (2005). Toward replacement parts for the brain: implantable biomimetic electronics as neural prostheses. Cambridge, Mass: MIT Press. ISBN 0-262-02577-9. 
  •[dead link] Jose Delgado's book Physical Control of the Mind]

Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • Brain pacemaker — Brain pacemakers are used to treat people who suffer from epilepsy, Parkinson s disease, major depression and other diseases. The pacemaker is a medical device that is implanted into the brain to send electrical signals into the tissue. Depending …   Wikipedia

  • Implant — can refer to: *Alien implants *Brain implant *Breast implant *Cochlear implant *Dental implant *Extraocular implant *Fetal tissue implant *Harrington implant *Implant (medicine) *Implant (Scientology) * Implant, The *Implantation *Microchip… …   Wikipedia

  • Brain–computer interface — Neuropsychology Topics Brain computer interface …   Wikipedia

  • Brain-computer interface — A brain computer interface (BCI), sometimes called a direct neural interface or a brain machine interface, is a direct communication pathway between a human or animal brain (or brain cell culture) and an external device. In one way BCIs,… …   Wikipedia

  • Implant cérébral — Les implants cérébraux, également appelés « BrainChips » ou « Brain implant » en anglais, sont des systèmes électroniques implantés dans le cerveau, afin de lire ou contrôler certains signaux cérébraux. Ils sont également… …   Wikipédia en Français

  • Implant — Жанр Electronic, electro industrial, Synthpop Годы С 1992 Страна …   Википедия

  • Brain — This article is about the brains of all types of animals, including humans. For information specific to the human brain, see Human brain. For other uses, see Brain (disambiguation). A chimpanzee brain The brain is …   Wikipedia

  • Brain-Computer Interface — Interface neuronale directe Pour les articles homonymes, voir IND et BCI. Schéma d une interface neuronale directe Une …   Wikipédia en Français

  • Brain-computer interface — Interface neuronale directe Pour les articles homonymes, voir IND et BCI. Schéma d une interface neuronale directe Une …   Wikipédia en Français

  • Brain-Washing (book) — Cover of Brain Washing, as published by the Church of Scientology in 1955. Brain Washing (subtitle: A Synthesis of the Russian Textbook on Psychopolitics), sometimes referred to as The Brainwashing Manual , is a book published by the Church of… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”