Flunisolide

Flunisolide

Systematic (IUPAC) name
(1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
Clinical data
Trade names	Aerobid
AHFS/Drugs.com	monograph
MedlinePlus	a681048
Pregnancy cat.	?
Legal status	?
Routes	Inhaled
Pharmacokinetic data
Protein binding	40% after oral inhalation
Half-life	1.8 hours
Identifiers
CAS number	3385-03-3 Y
ATC code	R01AD04 R03BA03
PubChem	CID 82153
DrugBank	APRD00976
ChemSpider	74144 Y
UNII	78M02AA8KF Y
KEGG	D00324 N
ChEBI	CHEBI:5106 Y
ChEMBL	CHEMBL1512 Y
Synonyms	6α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione acetone cyclic 16,17-acetal
Chemical data
Formula	C24H31FO6
Mol. mass	434.498 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,26,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1 Y Key:XSFJVAJPIHIPKU-XWCQMRHXSA-N Y
N(what is this?)  (verify)

Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid often prescribed as treatment for allergic rhinitis.

The principal mechanism of action of flunisolide is to activate glucocorticoid receptors, meaning it has an anti-inflammatory action.

This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it.v · Categories: Glucocorticoids Organofluorides Respiratory system drug stubs Wikimedia Foundation. 2010. Игры ⚽ Нужен реферат? United States Waiver of Inadmissibility He Depu Look at other dictionaries: flunisolide — An anti inflammatory corticosteroid used intranasally or by inhalation in the treatment of allergies and asthma. * * * flu·nis·o·lide flü nis ə .līd n a synthetic glucocorticoid C24H31FO6·1/2H2O administered as an oral inhalant to treat bronchial …   Medical dictionary flunisolide — n. an anti inflammatory corticosteroid drug used in the prevention and treatment of hay fever. It is administered as a nasal spray; the most common side effect is local irritation. Trade names: Syntaris …   The new mediacal dictionary ФЛЮНИЗОЛИД — (flunisolide) противовоспалительный кортикостероид, применяемый для долговременного лечения бронхиальной астмы и ринита. Назначается в виде ингаляций и спреев; характерные побочные эффекты: тошнота, рвота, головная боль, инфекционные заболевания… …   Толковый словарь по медицине Triamcinolone — Systematic (IUPAC) name (11β,16α) 9 fluoro 11,16,17,21 tetrahydroxypregna 1,4 diene 3,20 dione Clinical data Trade names …   Wikipedia Budesonide — Systematic (IUPAC) name 16,17 (butylidenebis(oxy)) 11,21 dihydroxy , (11 β,16 α) pregna 1,4 diene 3,20 dione Clinical data Trade names …   Wikipedia Beclometasone dipropionate — Systematic (IUPAC) name (8S,9R,10S,11S,13S,14S,16S,17R) 9 chloro 11 hydroxy 10,13,16 trimethyl 3 oxo 17 [2 (propionyloxy)acetyl] 6,7,8,9,10,11,12,13,14,15,16,17 dodecahydro 3H cyclo …   Wikipedia Ciclesonide — Systematic (IUPAC) name 2 [(1S, 2S, 4R, 8S, 9S,11S, 12S, 13R) 6 cyclohexyl 11 hydroxy 9, 13 dimethyl 16 oxo 5, 7 dioxapentacyclo [10.8.0.02,9.04, 8.013,18] icosa 14, 17 dien 8 yl] 2 oxoethyl 2 …   Wikipedia Fluticasone propionate — Systematic (IUPAC) name S (fluoromethyl) 6α,9 difluoro 11β, 17 dihydroxy 16α methyl 3 oxoandrosta 1, 4 diene 17β carbothioate, 17 propanoate Clinical data …   Wikipedia Corticosteroid — Corticosterone Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation,… …   Wikipedia Dexamethasone — Systematic (IUPAC) name (8S,9R …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”