Deflazacort

Deflazacort

Systematic (IUPAC) name
(11β,16β)-21-(acetyloxy)-11-hydroxy-2′-methyl-5′H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Routes	Oral
Pharmacokinetic data
Protein binding	40%
Metabolism	By plasma esterases, to active metabolite
Half-life	1.1–1.9 hours (metabolite)
Excretion	Renal (70%) and fecal (30%)
Identifiers
CAS number	14484-47-0
ATC code	H02AB13
PubChem	CID 26709
UNII	KR5YZ6AE4B Y
KEGG	D03671 Y
Chemical data
Formula	C25H31NO6
Mol. mass	441.517 g/mol
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Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant. It is sold in the United Kingdom by Shire under the trade name Calcort,^[1] in Brazil as Cortax, Decortil, and Deflanil, and in Honduras as Flezacor.^[2] It is not available in the United States.

Deflazacort is a prodrug. Its potency is around 70–90% that of prednisone.^[1]

References

1. ^ ^{a b} "Calcort". electronic Medicines Compendium. June 11, 2008. http://emc.medicines.org.uk/emc/assets/c/html/displaydoc.asp?documentid=20915.  Retrieved on October 28, 2008.
2. ^ (Portuguese) "Substâncias: DEFLAZACORT". Centralx. 2008. http://www.bulas.med.br/index.pl?C=A&V=66506F737449443D39333933266163743D73686F7752656164436F6D6D656E7473.  Retrieved on October 28, 2008.

This hormonal preparation article is a stub. You can help Wikipedia by expanding it.v · Categories: Glucocorticoids Prodrugs Oxazolines Acetate esters Systemic hormonal preparation stubs Wikimedia Foundation. 2010. Игры ⚽ Нужен реферат? Zamu Music Awards Western Sahara national football team Look at other dictionaries: deflazacort — Eng. Deflazacort Corticosteroide caracterizado por presentar escasa repercusión sobre los metabolismos hidrocarbonado y óseo, utilizado por vía oral en el tratamiento de procesos inflamatorios no infecciosos del globo ocular (iritis,… …   Diccionario de oftalmología deflazacort — noun A glucocorticoid prodrug used as an anti inflammatory and immunosuppressant …   Wiktionary Cloprednol — Systematic (IUPAC) name (9S,10R,11S,13S,14S,17R) 6 chloro 11,17 dihydroxy 17 (2 hydroxyacetyl) 10,13 dimethyl 9,11,12,14,15,16 hexahydro 8H cyclopenta[a]phenanthren 3 one …   Wikipedia Meprednisone — Systematic (IUPAC) name (16β) 17,21 dihydroxy 16 methylpregna 1,4 diene 3,11,20 trione Clinical data AHFS/Drugs.com …   Wikipedia Corticosteroid — Corticosterone Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation,… …   Wikipedia Cortisone — Not to be confused with cortisol (a.k.a. hydrocortisone), a similar compound with a similar name, genesis, and function. Cortisone …   Wikipedia Dexamethasone — Systematic (IUPAC) name (8S,9R …   Wikipedia Cortisol — Not to be confused with cortisone, a similar compound with a similar name, genesis, and function. Cortisol Systematic (IUPAC …   Wikipedia Corticosterone — Corticosterone …   Wikipedia Prednisone — For the active metabolite of prednisone which is also used as a drug including as eye drops, see prednisolone. Prednisone Systematic (I …   Wikipedia 18+ © Academic, 2000-2025 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”