Desonide

Desonide

Systematic (IUPAC) name
(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
Clinical data
Trade names	Desowen
AHFS/Drugs.com	monograph
MedlinePlus	a605025
Pregnancy cat.	C(US)
Legal status	?
Routes	topical
Identifiers
CAS number	638-94-8 Y
ATC code	S01BA11
PubChem	CID 12536
DrugBank	DB01260
ChemSpider	4470603 Y
UNII	J280872D1O Y
KEGG	D03696 Y
ChEBI	CHEBI:204734 Y
ChEMBL	CHEMBL1201109 N
Synonyms	(11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Chemical data
Formula	C24H32O6
Mol. mass	416.507
SMILES	eMolecules & PubChem
InChI InChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,20+,22-,23-,24+/m0/s1 Y Key:WBGKWQHBNHJJPZ-LECWWXJVSA-N Y
N(what is this?)  (verify)

Desonide is the generic name of a low potency topical corticosteroid that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, psoriasis and contact dermatitis in both adults and children. It has a fairly good safety profile^[1] and is available as a cream, ointment, lotion, and as a foam under the tradename Verdeso Foam.

References

1. ^ Wong, Vicky Kwan; Brian Fuchs, Mark Lebwohl (2004). "Overview on desonide 0.05%: a clinical safety profile". Journal of Drugs in Dermatology: JDD 3 (4): 393–7. PMID 15303783. 

This dermatologic drug article is a stub. You can help Wikipedia by expanding it.v · Categories: Corticosteroids Dermatologic drug stubs Wikimedia Foundation. 2010. Игры ⚽ Нужно решить контрольную? Deductive database Allegheny Mountain Collegiate Conference Look at other dictionaries: Désonide — Général No CAS …   Wikipédia en Français desonide and acetic acid otic solution — a solution of desonide and acetic acid used topically for the treatment of superficial external auditory canal infections accompanied by inflammation …   Medical dictionary desonide — An anti inflammatory corticosteroid used in topical preparations. * * * des·o·nide (desґə nīd) a low potency synthetic corticosteroid used topically for the relief of inflammation and pruritus in corticosteroid responsive dermatoses …   Medical dictionary 638-94-8 — Désonide Désonide Général No CAS …   Wikipédia en Français ATC code D07 — ATC codes D Dermatologicals D01 Antifungals for dermatological use D02 Emollients and protectives D03 Preparations for treatment of wounds and ulcers D04 Antipruritics, including antihistamines, anesthetics, etc. D05 Antipsoriatics D06 Antibiot …   Wikipedia Corticosteroid — Corticosterone Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation,… …   Wikipedia Deflazacort — Systematic (IUPAC) name (11β,16β) 21 (acetyloxy) 11 hydroxy 2′ methyl 5′H pregna 1,4 dieno[17,16 d]oxazole 3,20 dione Clinical data AHFS/ …   Wikipedia Cloprednol — Systematic (IUPAC) name (9S,10R,11S,13S,14S,17R) 6 chloro 11,17 dihydroxy 17 (2 hydroxyacetyl) 10,13 dimethyl 9,11,12,14,15,16 hexahydro 8H cyclopenta[a]phenanthren 3 one …   Wikipedia Meprednisone — Systematic (IUPAC) name (16β) 17,21 dihydroxy 16 methylpregna 1,4 diene 3,11,20 trione Clinical data AHFS/Drugs.com …   Wikipedia Cortisone — Not to be confused with cortisol (a.k.a. hydrocortisone), a similar compound with a similar name, genesis, and function. Cortisone …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”