Long acting beta-adrenoceptor agonist

Long acting beta-adrenoceptor agonist

Long acting beta-adrenoceptor agonists are usually prescribed for moderate to severe persistent asthma patients or patients with COPD. They are designed to replace the shorter acting B2-agonists such as salbutamol, as they have a duration of action of approximately 12 hours in comparison with the 4-6 hour duration of salbutamol, making them ideal candidates for twice-daily administration.

Some currently available long acting beta-adrenoceptor agonists are:
*Salmeterol
*Formoterol
*Bambuterol

Studies are currently underway into ultra-long-acting beta-adrenoceptor agonists which would have a duration of action of 24 hours, allowing for once-daily dosing:cite journal |author=Cazzola M, Matera MG, Lötvall J |title=Ultra long-acting beta 2-agonists in development for asthma and chronic obstructive pulmonary disease |journal=Expert Opin Investig Drugs |volume=14 |issue=7 |pages=775–83 |year=2005 |month=July |pmid=16022567 |doi=10.1517/13543784.14.7.775 |url=]
*Indacaterol

Footnotes


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