- Olodaterol
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Olodaterol Systematic (IUPAC) name 6-hydroxy-8-{(1R)-1-hydroxy-2-{[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino}ethyl}-4H-1,4-benzoxazin-3-one Clinical data Pregnancy cat. ? Legal status Investigational Routes Inhalation Identifiers ATC code None PubChem CID 11504295 ChEMBL CHEMBL605846 Chemical data Formula C21H26N2O5 Mol. mass 386.44 g/mol SMILES eMolecules & PubChem - InChI=1S/C21H26N2O5/c1-21(2,10-13-4-6-15(27-3)7-5-13)22-11-18(25)16-8-14(24)9-17-20(16)28-12-19(26)23-17/h4-9,18,22,24-25H,10-12H2,1-3H3,(H,23,26)/t18-/m0/s1
Key:COUYJEVMBVSIHV-SFHVURJKSA-N
Olodaterol is an ultra-long-acting beta-adrenoceptor agonist under development for the treatment of asthma. It has to be inhaled once daily.[1]
References
- ^ O'Byrne, P. M.; Van Der Linde, J.; Cockcroft, D. W.; Gauvreau, G. M.; Brannan, J. D.; Fitzgerald, M.; Watson, R. M.; Milot, J. et al. (2009). "Prolonged bronchoprotection against inhaled methacholine by inhaled BI 1744, a long-acting β2-agonist, in patients with mild asthma". Journal of Allergy and Clinical Immunology 124 (6): 1217–1221. doi:10.1016/j.jaci.2009.08.047. PMID 20004781.
Drugs for obstructive airway diseases: asthma/COPD (R03) Adrenergics, inhalants Salbutamol#/Levosalbutamol • Fenoterol • Terbutaline • Pirbuterol • Procaterol • Bitolterol • Rimiterol • Carbuterol • Tulobuterol • ReproterolLong acting β2-agonists (LABA)otherGlucocorticoids Anticholinergics/
muscarinic antagonistIpratropium bromide# • Oxitropium bromide • Tiotropium bromideMast cell stabilizers Cromoglicate • NedocromilXanthines Eicosanoid inhibition Thromboxane receptor antagonistsCombination products #WHO-EM. ‡Withdrawn from market. Clinical trials: †Phase III. §Never to phase III This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it. - InChI=1S/C21H26N2O5/c1-21(2,10-13-4-6-15(27-3)7-5-13)22-11-18(25)16-8-14(24)9-17-20(16)28-12-19(26)23-17/h4-9,18,22,24-25H,10-12H2,1-3H3,(H,23,26)/t18-/m0/s1