- Enprofylline
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Enprofylline Systematic (IUPAC) name 3-propyl-7H-purine-2,6-dione Clinical data Pregnancy cat. ? Legal status ? Identifiers CAS number 41078-02-8 ATC code ? PubChem CID 1676 DrugBank DB00824 ChemSpider 1613 UNII DT7DT5E518 ChEBI CHEBI:126237 ChEMBL CHEMBL279898 Chemical data Formula C8H10N4O2 Mol. mass 194.190 g/mol SMILES eMolecules & PubChem (what is this?) (verify) Enprofylline (3-Propylxanthine) is a xanthine derivative used in the treatment of asthma, which acts as a bronchodilator. It acts primarily as a competitive nonselective phosphodiesterase inhibitor with relatively little activity as a nonselective adenosine receptor antagonist.[1][2]
References
- ^ Lunell E, Svedmyr N, Andersson KE, Persson CG (1982). "Effects of enprofylline, a xanthine lacking adenosine receptor antagonism, in patients with chronic obstructive lung disease". European Journal of Clinical Pharmacology 22 (5): 395–402. PMID 6288396.
- ^ Laursen LC (December 1987). "Anti asthmatic effects and pharmacokinetics of enprofylline--a new xanthine derivate". Danish Medical Bulletin 34 (6): 289–97. PMID 3325233.
Drugs for obstructive airway diseases: asthma/COPD (R03) Adrenergics, inhalants Salbutamol#/Levosalbutamol • Fenoterol • Terbutaline • Pirbuterol • Procaterol • Bitolterol • Rimiterol • Carbuterol • Tulobuterol • ReproterolLong acting β2-agonists (LABA)otherGlucocorticoids Anticholinergics/
muscarinic antagonistMast cell stabilizers Cromoglicate • NedocromilXanthines Eicosanoid inhibition Thromboxane receptor antagonistsCombination products Adenosinergics Receptor ligands 2-(1-Hexynyl)-N-methyladenosine • 2-Cl-IB-MECA • 2'-MeCCPA • 5'-N-ethylcarboxamidoadenosine • ATL-146e • BAY 60–6583 • CCPA • CGS-21680 • CP-532,903 • GR 79236 • LUF-5835 • LUF-5845 • N6-Cyclopentyladenosine • Regadenoson • SDZ WAG 994 • UK-432,0978-Phenyl-1,3-dipropylxanthine • Acefylline • Aminophylline • Bamifylline • Caffeine • CGS-15943 • 8-Chlorotheophylline • CPX • CVT-6883 • Dimethazan • DPCPX • Fenethylline • Istradefylline • KF-26777 • MRE3008F20 • MRS-1220 • MRS-1334 • MRS-1706 • MRS-1754 • MRS-3777 • Paraxanthine • Pentoxifylline • Preladenant • Propentofylline • PSB-10 • PSB-11 • PSB 36 • PSB-603 • PSB-788 • PSB-1115 • Rolofylline • SCH-442,416 • SCH-58261 • Theobromine • Theophylline • VUF-5574 • ZM-241,385Reuptake inhibitors ENT inhibitorsVNT inhibitorsCategories:- Adenosine antagonists
- Bronchodilators
- Xanthines
- Phosphodiesterase inhibitors
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