- Ipratropium bromide/salbutamol
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Ipratropium bromide/salbutamol Combination of Ipratropium bromide Muscarinic antagonist Salbutamol Short-acting β2-adrenergic agonist Clinical data Pregnancy cat. C [1] Legal status ? Routes Inhalation Identifiers ATC code R03AK04 ChemSpider 21106326 (what is this?) bromide/salbutamol (verify) The combination preparation ipratropium bromide/salbutamol is a formulation containing ipratropium bromide and salbutamol sulfate (albuterol sulfate) used in the management of chronic obstructive pulmonary disease (COPD) and asthma(not an FDA approved usage)[2]. It is marketed by Boehringer Ingelheim as metered dose inhaler (MDI) and nebuliser preparations under the trade name Combivent. Besides, it is marketed by Dey, L.P. (Napa, California) under the brand name DuoNeb as a nebulizer. In Italy it is known as Breva.
Since Combivent contains a chlorofluorocarbon based propellant, it is being phased out in European Union countries.
DuoNeb controversy
DuoNeb has been a subject of recent Medicare and U.S. Food and Drug Administration (FDA) controversy. FDA has moved for regulation of generic competition to commercial product whereas Medicare has moved to limit reimbursement of commercial product. Dispute resolution will have a material economic impact on leading respiratory service providers, as well as patients.
External links
References
- ^ http://bidocs.boehringer-ingelheim.com/BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/Prescribing+Information/PIs/Combivent+IA/combivent.pdf
- ^ Expert Panel 3. Expert panel report 3: guidelines for the diagnosis and management of asthma.. ): National Institutes of Health. National Heart, Lung, and Blood Institute. 2007.
National Asthma Education and Prevention Program Expert Panel 3. Expert panel report 3: guidelines for the diagnosis and management of asthma. Bethesda (MD): National Institutes of Health. National Heart, Lung, and Blood Institute; 2007 Aug. NIH Publication No. 07-4051..
Drugs for obstructive airway diseases: asthma/COPD (R03) Adrenergics, inhalants Salbutamol#/Levosalbutamol • Fenoterol • Terbutaline • Pirbuterol • Procaterol • Bitolterol • Rimiterol • Carbuterol • Tulobuterol • ReproterolLong acting β2-agonists (LABA)otherGlucocorticoids Anticholinergics/
muscarinic antagonistIpratropium bromide# • Oxitropium bromide • Tiotropium bromideMast cell stabilizers Cromoglicate • NedocromilXanthines Eicosanoid inhibition Thromboxane receptor antagonistsCombination products Budesonide/formoterol • Fluticasone/salmeterol • Ipratropium bromide/salbutamol • Mometasone/formoterolThis drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it.