Levocabastine

drugbox
IUPAC_name = 1- [4-cyano-4-(4-fluorophenyl)-cyclohexyl] - 3-methyl-4-phenyl-piperidine-4- carboxylic acid

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width = 140
CAS_number = 79516-68-0
ATC_prefix = R01
ATC_suffix = AC02
ATC_supplemental = ATC|S01|GX02
PubChem = 54385
DrugBank = APRD01069
C = 26 | H = 29 | F = 1 | N = 2 | O = 2
molecular_weight = 420.519 g/mol
bioavailability =
protein_bound =
metabolism =
elimination_half-life = 3
pregnancy_AU = B3
pregnancy_US = C
legal_status = Rx-only
routes_of_administration = Ophthalmic, intranasalref|intranasal

Levocabastine is a selective second-generation H₁-receptor antagonist used for allergic conjunctivitis.

Levocabastine was discovered at Janssen Pharmaceutica in 1979.

References

* Pipkorn U, Bende M, Hedner J, Hedner T., A double-blind evaluation of topical levocabastine, a new specific H1 antagonist in patients with allergic conjunctivitis, Allergy. 1985 Oct;40(7):491-6.
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# cite web | url=http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/CPS-%20Monographs/CPS-%20(General%20Monographs-%20L)/LIVOSTIN%20NASAL%20SPRAY.html | title=RxMed: Pharmaceutical Information - LIVOSTIN NASAL SPRAY | accessdate=13 November | accessyear=2005