Mariptiline

Mariptiline: Mariptiline

Systematic (IUPAC) name

1a,10b-dihydrodibenzo[a,e]cyclopropa[c]cyclohepten-6(1H)-one O-(2-aminoethyl)oxime

Clinical data

Pregnancy cat. ?

Legal status ?

Identifiers

CAS number 60070-14-6

ATC code None

PubChem CID 44203

ChemSpider 40222

UNII E27T357050^Y

Chemical data

Formula C₁₈H₁₈N₂O

Mol. mass 278.35 g/mol

SMILES eMolecules & PubChem

Mariptiline (EN-207) is a tricyclic antidepressant (TCA) which was developed in the early 1980s, but was never marketed.^[1]^[2]

See also

Tricyclic antidepressant

References

^ David J. Triggle (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 0-412-46630-9. http://books.google.com/books?id=A0THacd46ZsC&lpg=PA1254&dq=mariptiline&pg=PA1254#v=onepage&q=mariptiline&f=false.

^ Hans-Jurgen Hess (1982). Annual Reports in Medicinal Chemistry Volume 17. Boston: Academic Press. pp. 400. ISBN 0-12-040517-2. http://books.google.com/books?id=gprdTFMiho4C&lpg=PA41&dq=mariptiline&pg=PA41#v=onepage&q=mariptiline&f=false.

v · d · eAntidepressants (N06A)

Specific reuptake inhibitors (RIs), enhancers (REs), and releasing agents (RAs)

Selective serotonin reuptake inhibitors (SSRIs)

Alaproclate • Citalopram • Escitalopram • Femoxetine • Fluoxetine^# • Fluvoxamine • Indalpine • Ifoxetine • Litoxetine • Lubazodone • Panuramine • Paroxetine • Pirandamine • Seproxetine • Sertraline^# • Vilazodone • Zimelidine^‡

Serotonin–norepinephrine reuptake inhibitors (SNRIs)

Bicifadine • Clovoxamine • Desvenlafaxine • Duloxetine • Levomilnacipran • Eclanamine • Milnacipran • Sibutramine • Venlafaxine

Serotonin–norepinephrine–dopamine reuptake inhibitors (SNDRIs)

Brasofensine • BTS-74,398 • Cocaine • Diclofensine • DOV-21,947 • DOV-102,677 • DOV-216,303 • EXP-561 • Fezolamine • JNJ-7925476 • NS-2359 • PRC200-SS • Pridefine • SEP-225,289 • SEP-227,162 • Tesofensine

Norepinephrine reuptake inhibitors (NRIs)

Amedalin • Atomoxetine/Tomoxetine • Binedaline • Ciclazindol • Daledalin • Esreboxetine • Lortalamine • Mazindol • Nisoxetine • Reboxetine • Talopram • Talsupram • Tandamine • Viloxazine

Dopamine reuptake inhibitors (DRIs)

Medifoxamine • Vanoxerine

Norepinephrine-dopamine reuptake inhibitors (NDRIs)

Amineptine • Bupropion/Amfebutamone^# • Cilobamine • Manifaxine • Methylphenidate • Nomifensine • Radafaxine • Tametraline

Norepinephrine-dopamine releasing agents (NDRAs)

Amphetamine • Befuraline • Lisdexamfetamine • Methamphetamine • Phenethylamine • Piberaline • Tranylcypromine

Serotonin-norepinephrine-dopamine releasing agents (SNDRAs)

4-Methyl-αMT • αET/Etryptamine • αMT/Metryptamine

Selective serotonin reuptake enhancers (SSREs)

Tianeptine

Others

Indeloxazine • Teniloxazine • Tramadol • Viqualine

Receptor antagonists and/or reuptake inhibitors

Serotonin antagonists and reuptake inhibitors (SARIs)

Etoperidone • Nefazodone • Trazodone

Noradrenergic and specific serotonergic antidepressants (NaSSAs)

Aptazapine • Esmirtazapine • Mianserin • Mirtazapine • Setiptiline/Teciptiline

Norepinephrine-dopamine disinhibitors (NDDIs)

Agomelatine

Serotonin modulators and stimulators (SMSs)

Vortioxetine

Tricyclic and tetracyclic antidepressants (TCAs/TeCAs)

Tricyclics

Amezepine • Amineptine • Amitriptyline^# • Amitriptylinoxide • Azepindole • Butriptyline • Cianopramine • Clomipramine • Cotriptyline • Cyanodothiepin • Demexiptiline • Depramine/Balipramine • Desipramine • Dibenzepin • Dimetacrine • Dosulepin/Dothiepin • Doxepin • Enprazepine • Fluotracen • Hepzidine • Homopipramol • Imipramine • Imipraminoxide • Intriptyline • Iprindole • Ketipramine • Litracen • Lofepramine • Losindole • Mariptiline • Melitracen • Metapramine • Mezepine • Naranol • Nitroxazepine • Nortriptyline • Noxiptiline • Octriptyline • Opipramol • Pipofezine • Propizepine • Protriptyline • Quinupramine • Tampramine • Tianeptine • Tienopramine • Trimipramine;

Tetracyclics

7-OH-Amoxapine • Amoxapine • Aptazapine • Azipramine • Ciclazindol • Ciclopramine • Esmirtazapine • Loxapine • Maprotiline • Mazindol • Mianserin • Mirtazapine • Oxaprotiline • Setiptiline/Teciptiline

Monoamine oxidase inhibitors (MAOIs)

Nonselective

Irreversible: Benmoxin • Echinopsidine • Iproclozide • Iproniazid • Isocarboxazid • Mebanazine • Metfendrazine • Nialamide • Octamoxin • Phenelzine • Pheniprazine • Phenoxypropazine • Pivalylbenzhydrazine • Safrazine • Tranylcypromine; Reversible: Caroxazone • Paraxazone;

MAO_A-Selective

Irreversible: Clorgiline; Reversible: Amiflamine • Bazinaprine • Befloxatone • Befol • Brofaromine • Cimoxatone • Esuperone • Harmala Alkaloids (Harmine, Harmaline, Tetrahydroharmine, Harman, Norharman, etc) • Methylene Blue • Metralindole • Minaprine • Moclobemide • Pirlindole • Sercloremine • Tetrindole • Toloxatone • Tyrima;

MAO_B-Selective

Irreversible: Ladostigil • Mofegiline • Pargyline • Rasagiline • Selegiline; Reversible: Lazabemide • Milacemide

Azapirones and other 5-HT_1A receptor agonists

Alnespirone • Aripiprazole • Befiradol • Buspirone • Eptapirone • Flesinoxan • Flibanserin • Gepirone • Ipsapirone • Oxaflozane • Tandospirone • Vilazodone • Zalospirone

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: PSO/PSI

mepr

dsrd (o, p, m, p, a, d, s), sysi/epon, spvo

proc(eval/thrp), drug(N5A/5B/5C/6A/6B/6D)

v · d · eTricyclics

Classes
Acridine • Anthracene • Dibenzazepine • Dibenzocycloheptene • Dibenzodiazepine • Dibenzothiazepine • Dibenzothiepin • Dibenzoxazepine • Dibenzoxepin • Phenothiazine • Pyridazinobenzoxazine • Pyridinobenzodiazepine • Thioxanthene

Antidepressants
7-OH-Amoxapine • Amezepine • Amineptine • Amitriptyline • Amitriptylinoxide • Amoxapine • Aptazapine • Azepindole • Azipramine • Butriptyline • Cianopramine • Ciclazindol • Ciclopramine • Clomipramine • Cotriptyline • Cyanodothiepin • Demexiptiline • Depramine/Balipramine • Desipramine • Dibenzepin • Dimetacrine • Dosulepin/Dothiepin • Doxepin • Enprazepine • Esmirtazapine • Fluotracen • Hepzidine • Homopipramol • Imipramine • Imipraminoxide • Intriptyline • Iprindole • Ketipramine • Litracen • Lofepramine • Losindole • Loxapine • Maprotiline • Mariptiline • Mazindol • Melitracen • Metapramine • Mezepine • Mianserin • Mirtazapine • Naranol • Nitroxazepine • Nortriptyline • Noxiptiline • Octriptyline • Opipramol • Oxaprotiline • Pipofezine • Pirandamine • Propizepine • Protriptyline • Quinupramine • Setiptiline/Teciptiline • Tandamine • Tampramine • Tianeptine • Tienopramine • Trimipramine

Antihistamines
Alimemazine • Azatadine • Clobenzepam • Cyproheptadine • Dacemazine • Deptropine • Desloratadine • Epinastine • Etymemazine • Hydroxyethylpromethazine • Isopromethazine • Isothipendyl • Ketotifen • Latrepirdine • Loratadine • Mebhydrolin • Mequitazine • Methdilazine • Olopatadine • Oxomemazine • Phenindamine • Pimethixene • Promethazine • Propiomazine • Rupatadine • Thiazinamium

Antipsychotics
Acetophenazine • Amoxapine • Asenapine • Butaclamol • Butaperazine • Carphenazine • Carpipramine • Chlorpromazine • Chlorprothixene • Ciclindole • Clocapramine • Clomacran • Clotiapine • Clozapine • Flucindole • Fluotracen • Flupentixol • Fluphenazine • Gevotroline • Homopipramol • Levomepromazine/Methotrimeprazine • Loxapine • Maroxepin • Mesoridazine • Metitepine/Methiothepin • Metoxepin • Mosapramine • Naranol • Olanzapine • Perazine • Perphenazine • Periciazine • Piperacetazine • Pipotiazine • Piquindone • Prochlorperazine • Promazine • Prothipendyl • Quetiapine • Sulforidazine • Thiethylperazine • Thiopropazate • Thioridazine • Thiothixene • Trifluoperazine • Triflupromazine • Zotepine • Zuclopenthixol

Others
Atiprosin • Carbamazepine • Carvedilol • Cyclobenzaprine • Licarbazepine • Methylene Blue • Monatepil • Oxcarbazepine • Oxitriptyline • Pirenzepine • Pirolate • Pitrazepin • Pizotifen • Profenamine

Categories:
Amines
Dibenzocycloheptenes
Oximes
Tricyclic antidepressants

Mariptiline

Systematic (IUPAC) name
1a,10b-dihydrodibenzo[a,e]cyclopropa[c]cyclohepten-6(1H)-one O-(2-aminoethyl)oxime
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	60070-14-6
ATC code	None
PubChem	CID 44203
ChemSpider	40222
UNII	E27T357050^Y
Chemical data
Formula	C₁₈H₁₈N₂O
Mol. mass	278.35 g/mol
SMILES	eMolecules & PubChem

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Look at other dictionaries:

Maprotiline — Systematic (IUPAC) name N Methyl 9,10 ethanoanthracene 9(10H) propanamine Clinical data AHFS/Drugs.com … Wikipedia
Loxapine — Systematic (IUPAC) name 2 Chloro 11 (4 methylpiperazin 1 yl)dibenzo[b,f][1,4]oxazepine Clinical data AHFS/Drugs.com … Wikipedia
Mirtazapine — Systematic (IUPAC) name … Wikipedia
Amitriptyline — Systematic (IUPAC) name … Wikipedia
Amoxapine — Systematic (IUPAC) name 2 Chloro 11 (piperazin 1 yl)dibenzo[b,f][1,4]oxazepine Clinical data Trade names Asendin … Wikipedia
Imipramine — Systematic (IUPAC) name 3 (10,11 dihydro 5H dibenzo[b,f]azepin 5 yl) N,N dimethylpropan 1 amine Clinical data Trade names … Wikipedia
Desipramine — Not to be confused with depramine. Desipramine Systematic (IUPAC) name 3 (10,11 dihydro 5H dibenzo[b,f]azepin 5 yl) N methylpropan 1 amine … Wikipedia
Clomipramine — Systematic (IUPAC) name 3 (3 chloro 10,11 dihydro 5H dibenzo[b,f]azepin 5 yl) N,N dimethylpropan 1 amine Clinical data Trade names … Wikipedia
Nortriptyline — Systematic (IUPAC) name 3 (10,11 dihydro 5H dibenzo[a,d] cyclohepten 5 ylidene) N methyl 1 propanamine Clinical data Trade names … Wikipedia
Doxepin — mixture of cis and trans isomers Systematic (IUPAC) name (E/Z) 3 (dibenzo[b,e]oxepin 11(6H) ylidene) N,N dimethylpropan 1 amine … Wikipedia

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Mariptiline

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References

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Mariptiline

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