- Pirenzepine
Pirenzepine (marketed by Boehringer Ingelheim under the trade-name Gastrozepin) is used in the treatment of
peptic ulcers , as it reducesgastric acid secretion and reducesmuscle spasm . It is in a class of drugs known asmuscarinic receptor antagonists -acetylcholine being the neurotransmitter of theparasympathetic nervous system which initiates the rest-and-digest state (as opposed to fight-or-flight), the result being an increase in gastric motility and digestion. It has no effects on the brain and spinal cord as it cannot diffuse through theblood-brain barrier .Pirenzepine has been investigated for use in
myopia control. [cite journal | author = Czepita D | title = Fundamentals of modern treatment of myopia | journal = Ann Acad Med Stetin | volume = 51 | issue = 2 | pages = 5–9 | year = 2005 | pmid = 16519089]References
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