Pirenzepine

Pirenzepine

Pirenzepine (marketed by Boehringer Ingelheim under the trade-name Gastrozepin) is used in the treatment of peptic ulcers, as it reduces gastric acid secretion and reduces muscle spasm. It is in a class of drugs known as muscarinic receptor antagonists - acetylcholine being the neurotransmitter of the parasympathetic nervous system which initiates the rest-and-digest state (as opposed to fight-or-flight), the result being an increase in gastric motility and digestion. It has no effects on the brain and spinal cord as it cannot diffuse through the blood-brain barrier.

Pirenzepine has been investigated for use in myopia control. [cite journal | author = Czepita D | title = Fundamentals of modern treatment of myopia | journal = Ann Acad Med Stetin | volume = 51 | issue = 2 | pages = 5–9 | year = 2005 | pmid = 16519089]

References


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Pirenzepine — ПИРЕНЦЕПИН ( Рirenzepine ) . 5,11 Дигидро 11 [4 метил 1 пиперазинил)ацетил] 6Н пиридо [2,3 b] [1,4]бензодиазепин 7 он дигидрохлорид. Выпускается в виде дигидрохлорида. Синонимы: Гастрозепин, Гастроцепин, Пирензепин, Аbrinac, Вisvanil, Duogest ral …   Словарь медицинских препаратов

  • pirenzepine — noun A drug used in the treatment of peptic ulcers, one of the muscarinic receptor antagonists …   Wiktionary

  • pirenzepine — An anticholinergic agent exhibiting relative specificity for suppression of gastric hydrochloric acid secretion; relatively free of anticholinergic side effect s; used in the treatment of ulcer …   Medical dictionary

  • pirenzepine hydrochloride — pir·en·ze·pine hy·dro·chlo·ride (pir″ən zĕґpēn) an antagonist of certain muscarinic receptors that has minimal anticholinergic effects and does not cross the blood brain barrier, used to inhibit gastric secretion in peptic… …   Medical dictionary

  • Clozapine — Not to be confused with clonazepam or Klonopin. Clozapine Systematic (IUPAC) name …   Wikipedia

  • Trifluoperazine — Systematic (IUPAC) name 10 [3 (4 methylpiperazin 1 yl)propyl] 2 (trifluoromethyl) 10H phenothiazine Clinical data AHFS/ …   Wikipedia

  • Fluphenazine — Systematic (IUPAC) name 2 [4 [3 [2 (trifluoromethyl) 10H phenothiazin 10 yl]propyl]piperazin 1 yl]ethanol Clinical data …   Wikipedia

  • Olanzapine — Systematic (IUPAC) name 2 methyl 4 (4 methyl …   Wikipedia

  • Perphenazine — Systematic (IUPAC) name 2 [4 [3 (2 chloro 10H phenothiazin 10 yl) propyl]piperazin 1 yl]ethanol Clinical data AHFS/Drugs.com …   Wikipedia

  • Loxapine — Systematic (IUPAC) name 2 Chloro 11 (4 methylpiperazin 1 yl)dibenzo[b,f][1,4]oxazepine Clinical data AHFS/Drugs.com …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”