Piberaline

Drugbox
IUPAC_name = [4-(phenylmethyl)piperazin-1-yl] -pyridin-2-ylmethanone


CAS_number = 39640-14-7
CAS_supplemental = 70062-37-2
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PubChem = 65975
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chemical_formula =
C=17 | H=19 | N=3 | O=1
molecular_weight = 281.35 g/mol
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Piberaline fumarate (EGYT-475, Trelibet) is a piperazine derivative drug invented in the 1980s. It has stimulant and antidepressant effects which are thought to be due largely to its active metabolite benzylpiperazine. [ Tekes K, Tothfalusi L, Malomvolgyi B, Herman F, Magyar K. Studies on the biochemical mode of action of EGYT-475, a new antidepressant. Polish Journal of Pharmacology and Pharmacy. 1987 Mar-Apr;39(2):203-11. ] It was researched to a limited extent in Hungary and Spain, but was not widely accepted and does not seem to be in current use, although a closely related drug Befuraline with similar effects has been slightly more successful.

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