Mebhydrolin

Mebhydrolin
Mebhydrolin
Systematic (IUPAC) name
5-benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat. Not established[1]
Legal status  ?
Routes oral[1]
Identifiers
CAS number 524-81-2 YesY 6153-33-9[2]
ATC code R06AX15
PubChem CID 22530
ChemSpider 21129 YesY
UNII 9SUK9B7XVY N
KEGG D08161 YesY
Synonyms 9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-β-carboline, Incidal, Omeril, diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate[3]
Chemical data
Formula C19H20N2[4] 
Mol. mass 276.376 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries. It is also called Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to enhance the performance-deficit effects of alcohol.[5]

References

  1. ^ a b "FABAHISTIN 50 mg (Tablets)" (HTML). South African Electronic Package Inserts. 1970-09. http://www.intekom.com/pharm/bayer/fabahist.html. Retrieved 2007-03-02. [dead link]
  2. ^ = &term = diazoline "Diazoline" (HTML). National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode = &term = diazoline. Retrieved 2007-03-02. 
  3. ^ = &term = mebhydroline "Mebhydroline" (HTML). National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. http://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode = &term = mebhydroline. Retrieved 2007-03-02. 
  4. ^ "Mebhydrolin chemical information" (HTML). PubChem. http://www.chemindustry.com/chemicals/969111.html. Retrieved 2007-03-02. 
  5. ^ Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK (October 1981). "Interaction between ethanol and antihistamines: 3. mebhydrolin". Med. J. Aust. 2 (9): 477–9. PMID 6119605. 
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